Companies across the USA are actively searching for a skilled regulatory manager to guide compliance strategy and mitigate risk in an increasingly complex marketplace. This remote opportunity offers 500+ open positions for professionals ready to shape regulatory frameworks from anywhere in the country. As industries face tighter scrutiny, demand for regulatory manager jobs in the USA continues to climb, making this an ideal time to explore new career paths.
Successful candidates bring strong knowledge of federal and state compliance standards, along with the ability to interpret evolving regulations and translate them into actionable policies. Employers seek a regulatory manager who can communicate clearly with cross-functional teams, manage documentation with precision, and anticipate regulatory shifts before they impact operations. Analytical thinking, attention to detail, and familiarity with industry-specific compliance software are highly valued. Leadership experience and a proactive approach to risk management further strengthen a candidate's profile among regulatory manager vacancies nationwide.
Remote work has become a standard arrangement for regulatory manager positions, allowing professionals to collaborate with legal, quality, and operations teams through digital platforms rather than traditional office settings. Organizations across the USA increasingly hire a regulatory manager who can maintain compliance oversight remotely, reflecting a broader shift toward distributed regulatory teams. This flexibility, combined with steady industry demand, makes remote regulatory roles both accessible and highly competitive.
If you're ready to advance your career and make a meaningful impact on compliance strategy, now is the time to act. Explore current regulatory manager jobs in the USA through Global Work AI and take the next step toward a rewarding remote opportunity.
Telix Pharmaceuticals (AMER)
Manage and organize regulatory submissions and documents, ensuring compliance and efficient workflows. Collaborate with teams to prepare compliant submission documents and manage deadlines.
remote, United StatesFull TimeSenior (5+ years)CorVel Career Site
Lead Nevada compliance framework, establishing standards for regulatory oversight and accountability. Monitor critical deadlines and ensure timely completion of actions. Partner with Litigation & Resolution Specialist to support legal strategy and complex claims.
remote, NV, United States$93k – $120k/yrFull TimeSenior (5+ years)
Exelixis
Manage regulatory submission planning, publishing, quality control, and lifecycle management for clinical and commercial programs. Ensure timely, high-quality submissions that meet Health Authority requirements.
remote, United States$165k – $209k/yrFull TimeSenior (5+ years)
Cardinal Health
Authorship and review of eCTDs for drug submissions to health authorities. Support regulatory strategy for drug development and ensure compliance with NDA, ANDA, MAA, and NDS approvals. Oversee risk management reviews and participate in change management processes.
remote, United States$125k – $179k/yrFull TimeLead / Manager
Jobgether
Lead regulatory compliance activities across Nevada operations, ensuring adherence to workers’ compensation laws and internal standards. Oversee high-risk regulatory matters, manage escalations, and support timely resolutions.
remote, NV, United States$93k – $120k/yrFull TimeSenior (5+ years)
Accumulus Technologies
Develop and implement regulatory strategies aligned with company goals and customer needs. Provide guidance on global CMC lifecycle management, post-approval changes, and collaborative reviews.
remote, United StatesFull TimeDirector
Siemens Healthineers
Prepare and maintain regulatory submissions, including FDA 510(k) and IVDR Class C recertifications. Serve as a subject matter expert in Regulatory Affairs, guiding design control and product development teams.
remote, United States$127k – $174k/yrFull TimeSenior (5+ years)Jobgether
Monitor legislative developments and regulatory activities, identifying risks and opportunities. Build relationships with regulators and industry stakeholders. Lead advocacy initiatives and represent the organization in coalitions.
remote, United States$110k – $157k/yrFull TimeSenior (5+ years)
Amgen
Manage the strategy and execution of CMC post-market supplements and facility registrations. Coordinate regulatory filings, assess impacts of deviations, and maintain product compliance. Facilitate agency interactions and support change management activities.
remote, United States$113k – $153k/yrFull TimeJunior (<2 years)
Enveda
Lead the development and execution of global regulatory strategies for small-molecule medicines. Oversee regulatory submissions including INDs, NDAs, and briefing documents. Represent the company with health authorities and ensure compliance with regulatory requirements.
remote, United States$220k – $250k/yrFull TimeDirector
Branch Financial, LLC
Track legislation and regulatory developments affecting Branch's operations. Build relationships with regulators and legislators, and lead outreach on new products. Represent Branch in industry coalitions and translate laws into guidance for internal teams.
remote, AZ, United StatesFull TimeSenior (5+ years)Amgen
Ensure compliance with regulations and laws related to company products. Support the Global Regulatory Team in US regulatory activities, manage local regulatory submissions, and maintain local product compliance.
remote, United States$113k – $153k/yrFull TimeMiddle (2-4 years)
Sarah Cannon Research Institute
Oversee regulatory operations for Clinical Operations, ensuring compliance with FDA regulations. Develop and implement regulatory policies and procedures, manage regulatory affairs for clinical trials, and maintain relationships with industry partners and the FDA.
remote, United StatesFull TimeJunior (<2 years)
Young Innovations
Coordinate and execute regulatory affairs activities for medical devices, drugs, and tissue products. Develop regulatory plans, manage submissions for marketing authorizations, and ensure compliance with internal and external standards.
remote, United States$105k – $115k/yrFull TimeLead / Manager
Harrow, Inc.
Develop and execute regulatory CMC registration and post-approval strategies for ophthalmic products. Oversee regulatory matters for compounded drug formulations and supervise marketing material development. Ensure compliance with filing requirements and lead the Regulatory team.
remote, United StatesFull TimeLead / Manager
Penn State University
Develop and administer regulatory compliance programs, oversee study start-up and trial life-cycle responsibilities, and maintain regulatory documentation.
remote, United States$81k – $122k/yrFull TimeSenior (5+ years)
Topcon Positioning Systems
Support the development and improvement of the Quality Management System, ensuring compliance with FDA QMSR and ISO 13485. Manage risk for medical device software, including risk analysis and verification.
remote, United States$100k – $120k/yrFull TimeSenior (5+ years)
Federal Express Corporation
Lead a team of regulatory professionals in executing brokerage compliance functions. Oversee compliance activities related to customs bond obligations and manage financial outcomes related to penalty mitigation.
remote, Memphis, TN, United States$108k – $178k/yrFull TimeLead / Manager
Keysight Technologies, Inc.
Lead regulatory compliance activities for product market access in the Americas. Interpret and communicate regulatory requirements, providing internal consultancy. Manage relationships with regulators and certification bodies, and support sales teams with compliance inquiries.
remote, United States$132k – $238k/yrFull TimeSenior (5+ years)Amgen
Lead the development of Amgen's positions on regulatory policies, engaging with external stakeholders and internal experts. Foster relationships with U.S. trade associations and manage regulatory reform initiatives.
remote, United States$155k – $210k/yrFull TimeDirector
Revance
Manage regulatory submissions related to advertising and promotional materials, ensuring compliance with FDA requirements. Oversee the preparation and submission of regulatory documents for INDs, CTAs, and BLAs, collaborating with cross-functional teams.
remote, United StatesFull TimeLead / Manager
Parexel
Shape and execute global regulatory plans, translating strategy into actionable steps with clear milestones. Lead regulatory plan execution, ensuring alignment with strategic objectives and managing complex timelines.
remote, United StatesFull TimeSenior (5+ years)
SOLVENTUM
Develop and execute regulatory strategies for product approvals, guiding regulatory authority interactions and submission activities. Collaborate with R&D, Quality Assurance, and Clinical Affairs to integrate regulatory requirements into product development.
remote, United States$212k – $291k/yrFull TimeDirector
Onward
Manage regulatory compliance for new market launches, ensuring operational processes meet state and local requirements. Oversee ongoing driver and vehicle compliance, including documentation and monitoring of expirations.
remote, United States$85k – $105k/yrFull TimeSenior (5+ years)
Lundbeck
Provide regulatory advertising and promotional support for product launches and lifecycle management. Review and assess advertising materials for compliance with FDA regulations. Serve as a regulatory partner in cross-functional teams, identifying regulatory risks and proposing compliant solutions.
remote, MA, United States$140k – $165k/yrFull TimeSenior (5+ years)
Primergy
Monitor and analyze regulatory proceedings and decisions from FERC and state Public Utility Commissions. Prepare regulatory intelligence reports and strategic recommendations for leadership. Support regulatory filings and stakeholder engagement activities.
remote, United StatesFull TimeSenior (5+ years)
Regeneron Pharmaceuticals
Manage US and Global regulatory activities related to advertising and promotion of marketed and pipeline products. Provide regulatory advice to Commercial teams and Medical Affairs, review promotional materials, and ensure compliance with FDA regulations.
remote, United States$151k – $246k/yrFull TimeSenior (5+ years)Regeneron Pharmaceuticals
Manage US regulatory activities related to advertising and promotion of marketed products. Provide regulatory advice on product messages and materials, ensuring compliance with laws and regulations. Review promotional materials and interact with FDA OPDP/APLB to support product launches.
remote, United States$110k/yrFull TimeJunior (<2 years)Regeneron Pharmaceuticals
Manage US regulatory activities related to advertising and promotion of marketed products. Provide regulatory advice to Commercial teams and Medical Affairs, review promotional materials, and ensure compliance with FDA regulations.
remote, United States$129k – $210k/yrFull TimeJunior (<2 years)
PowerLines
Lead the Regulatory Team, overseeing a Program Manager, Analyst, and Senior Advisors. Develop and execute PowerLines’ regulatory strategy, including engagement with state public utilities commissions on rate cases and rulemakings. Mentor junior team members and manage talent recruitment.
remote, United States$175k – $225k/yrFull TimeDirector
Zoetis
Lead global surveillance workstreams, monitor and communicate regulatory requirements, coordinate cross-functional impact assessments, and manage regulatory intelligence communications.
remote, United States$120k – $180k/yrFull TimeLead / Manager
Eqvilent
Lead compliance projects including implementation of regulatory requirements, integration for new market access, and regulatory remediation. Manage project timelines, resources, and stakeholder expectations while coordinating cross-functional teams.
remote (anywhere)Full TimeSenior (5+ years)
Veristat
Lead and manage regulatory affairs projects, ensuring high-quality execution. Collaborate with internal teams and external partners, integrating consulting activities across various areas including CMC, quality, regulatory, and clinical.
remote, United States$128k – $144k/yrFull TimeSenior (5+ years)
Farmer's Business Network
Develop regulatory strategies for Crop Protection products in the USA and Canada. Oversee EPA and PRMA submissions, manage submission timelines, and coordinate label preparation. Identify regulatory issues, provide guidance to stakeholders, and propose improvements to the registration process.
remote, United StatesFull TimeSenior (5+ years)
Kyverna Therapeutics
Develop and execute regulatory strategies aligned with corporate objectives. Manage preparation and submission of regulatory documents including INDs, BLAs, and safety reports.
remote, United States$151k – $171k/yrFull TimeJunior (<2 years)
Vera Therapeutics, Inc.
Prepare, publish, and compile regulatory submission documents in compliance with global requirements. Format complex Word documents, maintain submission templates, and ensure consistency across documents.
remote, United States$120k – $170k/yrFull TimeSenior (5+ years)Amgen
Lead writing activities for complex regulatory submissions, authoring documents such as Clinical Study Reports and Investigator Brochures. Conduct formal reviews and approvals of documents, supervise contract and freelance writers, and mentor junior medical writers.
remote, United States$140k – $189k/yrFull TimeSenior (5+ years)
Liquidia
Support regulatory strategy development and execution for drug-device combination products. Collaborate with Clinical Development, Safety, and Project Management on submission planning and lifecycle management.
remote, United StatesFull TimeSenior (5+ years)
Thermo Fisher Scientific
Lead the development and execution of global regulatory plans, ensuring alignment with strategic objectives. Facilitate Global Regulatory Subteam meetings, manage timelines, and document decisions. Collaborate with cross-functional teams to drive regulatory deliverables and anticipate challenges.
remote, Morrisville, NC, United StatesFull TimeSenior (5+ years)Lundbeck
Provide regulatory advertising and promotional support for product launches and lifecycle management. Review and assess advertising materials for compliance with FDA regulations. Serve as a regulatory partner in cross-functional teams, identifying risks and proposing compliant solutions.
remote, MA, United States$140k – $165k/yrFull TimeSenior (5+ years)10,000,000+ more jobs available!
