Companies across the USA are actively expanding their IT teams, and 500+ application support engineer remote jobs are currently open for skilled professionals ready to keep critical systems running smoothly. This remote-first opportunity allows candidates from anywhere in the country to support enterprise applications, troubleshoot issues, and ensure seamless user experiences. Demand for this role continues to grow as organizations shift toward digital-first operations.
Successful candidates typically bring strong troubleshooting skills, familiarity with SQL, scripting languages, and ticketing systems like Jira or ServiceNow. Experience with cloud platforms, API integrations, and Windows/Linux environments proves valuable, alongside excellent communication skills for coordinating with cross-functional teams. Employers looking to hire an application support engineer often prioritize candidates who can balance technical depth with customer-facing problem solving.
Remote application support engineer positions in the USA offer flexible schedules while maintaining strict SLAs and uptime commitments. Many companies embrace distributed teams, using collaboration tools to bridge time zones and ensure round-the-clock coverage. The nationwide hiring outlook remains strong, with steady demand for professionals who can adapt to hybrid IT infrastructures and evolving cloud technologies.
If you're ready to advance your career, explore the latest application support engineer vacancies available through Global Work AI. Our platform connects talented professionals with forward-thinking companies seeking remote talent across the USA. Take the next step and discover a role that matches your skills and ambitions today.
Pax8
Support Operations Engineer I | United States | Remote Pax8 is hiring a Support Operations Engineer I in the United States to turn support data, automation, ServiceNow solutions, and emerging AI...
remote, United States$65k – $100k/yrFull TimeJunior (<2 years)
Everbridge
Everbridge, a global leader in critical event management, is seeking a Junior Technical Support Engineer to help customers resolve technical issues with Everbridge products. In this role, you’ll...
remote, United States$56k – $70k/yrFull TimeJunior (<2 years)
Vultr
Who We Are Vultr is on a mission to make high-performance cloud infrastructure easy to use, affordable, and locally accessible for enterprises and AI innovators around the world. With 33 global cloud...
remote, Alabama, United States$60k – $81k/yrFull TimeLead / Manager
Blueprint Technologies
About Blueprint Blueprint is a technology solutions firm headquartered in Bellevue, Washington, with teams across the United States. We help organizations turn complex challenges into meaningful...
remote, United States$90k – $100k/yrFull TimeJunior (<2 years)
Qualia
At Qualia, we've built the leading B2B real estate technology that transforms the home buying and selling experience into a simple, secure, and enjoyable process. Our SMB and Enterprise products...
remote, Texas, United StatesFull TimeSenior (5+ years)
Levanta
Levanta is the creator affiliate platform built for modern e-commerce. We connect brands, creators, publishers, and marketplaces through a single platform for creator discovery, activation,...
remote, United StatesFull TimeJunior (<2 years)
Spreedly
About Us: Spreedly is the Intelligent Payments Platform for businesses that want to own their payments strategy. Founded in 2007 and headquartered in Durham, NC, we give merchants, platforms, and...
remote, United StatesFull TimeJunior (<2 years)
Great Minds
Who We Are Great Minds is a high-growth, mission-driven organization founded by educators in 2007. As a for-profit, Public Benefit Corporation, we believe all students deserve access to meaningful,...
remote, United States$57k – $61k/yrFull TimeJunior (<2 years)
RYZ Labs
Technical Support Engineer Our client is an AI sales coach that provides sales reps with real-time guidance during live calls, pre-call dossiers, and automatic CRM sync. Selling to enterprise sales...
remote, United StatesFull TimeJunior (<2 years)
Vectra
Vectra® is the leader in AI-driven threat detection and response for hybrid and multi-cloud enterprises. The Vectra AI Platform delivers integrated signal across public cloud, SaaS, identity, and...
remote, United States$80k – $90k/yrFull TimeSenior (5+ years)
Cimpress
Who We Are Cimpress Technology develops cutting-edge, best-in-world software that our mass customization businesses use to create personalized products for over 17 million global customers. Our Mass...
remote, United StatesFull TimeSenior (5+ years)Cimpress
Who We Are Cimpress Technology develops cutting-edge, best-in-world software that our mass customization businesses use to create personalized products for over 17 million global customers. Our Mass...
remote, United StatesFull TimeJunior (<2 years)
Workiva Inc.
Ability to support APAC hours working from 3PM - 12AM Pacific Time As a Software Support Engineer, you play a crucial role in bridging the gap between our Customer Support and the Engineering teams...
remote, United States$78k/yrFull TimeJunior (<2 years)
City of Durham
Position Description Work, Serve, Thrive. With the City of Durham Advance in your career while making a real difference in the community you serve. Hiring Range: $68,038-86,763 Work Day/Hours: 8am -...
remote, NC, United States$68k – $87k/yrFull TimeJunior (<2 years)Lumen Solutions Group Inc
Company Description Lumen Solutions Group Inc. is a technology consulting Services company based in Florida. We provide a wide array of experienced business and IT professionals supporting clients...
remote, DC, United StatesFull TimeJunior (<2 years)
Honeydew
The Mission 💪 Our mission is to ensure that no one in the world has to suffer from a treatable skin disease because of an access issue ever again. About Honeydew 👋 Honeydew is building a platform...
remote, United StatesFull TimeJunior (<2 years)
Perseus Group
Support Engineer — TargetCRM / Notify360 Location: Remote — United States or Canada Employment Type: Full-time/Remote Team: TargetCRM / Notify360, Ideal Computer Systems Ideal Computer Systems and...
remote, United States$115k – $141k/yrFull TimeMiddle (2-4 years)Nextens
About the Business LexisNexis Risk Solutions is the essential partner in the assessment of risk. Within our Business Services vertical, we offer a multitude of solutions focused on helping businesses...
remote, United States$65k/yrFull TimeJunior (<2 years)
BrightClaim
Engineer - Application Support S Ready to turn bold ideas into real-world impact? At Genpact, we don’t just adapt to change, we lead it. AI and digital innovation are transforming the way businesses...
remote, United States$50k – $63k/yrFull TimeJunior (<2 years)
RELX
About the Business LexisNexis Risk Solutions is the essential partner in the assessment of risk. Within our Business Services vertical, we offer a multitude of solutions focused on helping businesses...
remote, United States$65k/yrFull TimeJunior (<2 years)
Point of Rental Software
About the Team When a rental business hits a problem it can't solve, it comes to the Point of Rental Support team. We're the people who know the product inside and out and get customers back to...
remote, Fort Worth, TX, United States$70k – $85k/yrFull TimeLead / Manager
Replicant
At Replicant, we believe AI should work for people, starting with customer service. That’s why we built a platform that helps contact centers resolve more requests, proactively identify issues, and...
remote, United StatesFull TimeJunior (<2 years)
MWDN
MWDN is a global IT outstaffing company with 23+ years of experience that connects exceptional tech talent with leading companies across Israel, the USA, Great Britain, and Western Europe. We offer...
remote, United StatesFull TimeJunior (<2 years)
vivi.io
Overview: Vivi is the campus operating system that unifies every display and device across schools. Trusted by thousands of schools worldwide, Vivi helps schools improve teaching, strengthen...
remote, United StatesFull TimeMiddle (2-4 years)
Allata
Allata is a global consulting and technology services firm founded in 2016, with 350+ employees across the US, India, and Argentina. We partner with some of the world's largest enterprises to move AI...
remote, United StatesFull TimeJunior (<2 years)
Town Web
Senior Support Engineer Town Web · HeyGov · ClerkMinutes. Remote, Central US hours. $85,000 to $105,000 a year. Open to candidates in the United States, Canada, the United Kingdom, and Ireland. About...
remote, United States$85k – $105k/yrFull TimeSenior (5+ years)
Syngene International Limited
Job Title: Senior Application Support Engineer Job Location: Remote About Syngene: Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization...
remote, United StatesFull TimeSenior (5+ years)
ABACUS
Position Summary We are seeking a customer-focused and technically skilled Support Engineer - Software to join our Software team. In this role, you will serve as the primary technical contact for...
remote, United StatesFull TimeMiddle (2-4 years)
Sciemo
about sciemo Sciemo builds AI for consumer goods: technology that helps businesses make faster, smarter, and more human decisions across the entire IBP process. From optimizing promotions to...
remote, United StatesPart TimeJunior (<2 years)
Docusign
Company Overview Docusign brings agreements to life. Over 1.5 million customers and more than a billion people in over 180 countries use Docusign solutions to accelerate the process of doing business...
remote, United StatesFull TimeMiddle (2-4 years)
Cotiviti
Overview The Sr. Support Engineer plays a critical role in providing advanced technical and functional support for Smart Trading solutions, including Transaction Management, XES, and related trading...
remote, United States$110k – $148k/yrFull TimeSenior (5+ years)
Nous Research
The Role Nous is building at the frontier of agentic AI, and we’re looking for a Support Engineer to own the critical interface between our users and the systems behind that work. You’ll solve issues...
remote, United StatesFull TimeJunior (<2 years)
Thorn
At Thorn, our cause is our code. We are a nonprofit whose mission of defending children from sexual exploitation and abuse is deeply embedded within our core—a shared code that drives us to do...
remote, United States$79k – $109k/yrFull TimeSenior (5+ years)
BusRight
About BusRight More than 26 million students ride approximately 500,000 school buses every day. At BusRight, we are building the modern operating system for school transportation, helping districts...
remote, United StatesFull TimeJunior (<2 years)
InductiveHealth
Mission + People + Culture With a corporate Mission to stop disease through technology, InductiveHealth is the market leader in software-as-a-service (SaaS) solutions to public health agencies. Our...
remote, United States$95k – $105k/yrFull TimeSenior (5+ years)Origami Risk
Overview Client Support professionals are responsible for delivering client-facing, high-quality, timely, and technically accurate support to Origami Risk clients. This job family spans foundational...
remote, United States$66k – $97k/yrFull TimeJunior (<2 years)
AnewHealth
AnewHealth is one of the nation’s leading pharmacy care management companies that specializes in caring for people with the most complex, chronic needs—wherever they call home. We enable better...
remote, United StatesFull TimeSenior (5+ years)
Zact Inc.
About Us Zact is a Fintech innovator dedicated to a singular idea: Organizations need simpler expense and payment management systems that align the spending employee with finance and accounting while...
remote, United StatesFull TimeSenior (5+ years)
Blue Mantis
Desktop Support Engineer L1 - Remote US Only Department: Blue Mantis Employment Type: Full Time Location: Onsite Compensation: $21.00 - $25.00 / hour Description The L1 EUX Engineer provides support...
remote, United States$42k – $50k/yrFull TimeMiddle (2-4 years)American Cancer Society
At the American Cancer Society, we're working to end cancer as we know it, for everyone. Our employees and 1.3 million volunteers are raising the bar every single day. We are a culture comprised of...
remote, United States$73k – $85k/yrFull TimeMiddle (2-4 years)10,000,000+ more jobs available!
