The demand for a senior research scientist continues to grow as organizations across the USA invest heavily in innovation and data-driven discovery. This remote position offers 500+ open roles for professionals eager to lead impactful projects while enjoying the flexibility of working from anywhere in the country. Companies are actively seeking talent to fill senior research scientist jobs in remote settings, making this an excellent time to explore new opportunities.
Successful candidates typically bring advanced expertise in experimental design, statistical modeling, and data interpretation, paired with strong written and verbal communication skills. Employers hiring for senior research scientist positions often look for a proven track record of publishing research, managing cross-functional teams, and translating complex findings into actionable insights. Familiarity with programming languages such as Python or R, along with experience in machine learning frameworks, is increasingly valued. Adaptability and a collaborative mindset are essential, as many teams operate across different time zones and disciplines.
Remote work for a senior research scientist in the USA has become a mainstream model, allowing companies to access specialized talent regardless of geography. This shift has fueled a steady rise in senior research scientist vacancies, particularly within biotech, pharmaceuticals, and technology sectors. Organizations are adapting their hiring outlook to prioritize flexible, output-driven collaboration, making remote research roles both sustainable and highly competitive in today’s market.
If you are ready to advance your career and contribute to groundbreaking research, now is the perfect time to explore senior research scientist jobs available through Global Work AI. Whether you are looking to hire a senior research scientist or find your next remote opportunity, Global Work AI connects passionate professionals with organizations shaping the future of science and innovation.
Jobgether
Lead complex health services research and evaluation projects, providing expertise on health policies and healthcare delivery models. Oversee project operations, ensuring timely deliverables and coordination among team members.
remote, DC, United States$63k – $105k/yrPart TimeSenior (5+ years)
RAND
Lead the integration of AI into RAND's research and business processes. Recommend frameworks for AI adoption, design approaches for real projects, and advise on tools and resources. Propose governance and measurement strategies for AI deployment and assess evidence-based measures of success.
remote, United States$172k – $283k/yrPart TimeSenior (5+ years)
Cedars-Sinai
Participate in biomedical research projects using programming, data mining, statistics, and machine learning. Responsibilities include querying databases, data cleaning, deploying models, and leading scientific communication.
remote, West Hollywood, CA, United StatesFull TimeSenior (5+ years)
American Institutes for Research
Lead the development and maintenance of the International Data Explorer (IDE), ensuring quality assurance and technical reviews of assessment data. Manage project schedules and deliverables, coordinating tasks across teams and subcontractors.
remote, United States$120k – $135k/yrPart TimeSenior (5+ years)
Carrum Health
Redesign care delivery workflows, optimize staffing and queue structures, and build capacity models. Conduct operational experiments to measure the impact of changes and monitor performance metrics.
remote, United States$175k – $200k/yrFull TimeSenior (5+ years)
Lilly
Lead scientific strategy for early-stage clinical trials, including study design and data interpretation. Author and review clinical and regulatory documents, oversee study conduct, and drive dose-escalation discussions.
remote, United States$153k – $284k/yrFull TimeSenior (5+ years)
Xperteez Technology
Evaluate AI models for dual-use biological risks, running technical assessment pipelines and analyzing model behavior. Synthesize findings into clear evaluation reports and risk summaries for partners and regulatory bodies.
remote, United StatesFull TimeSenior (5+ years)
Horizon3
Identify and drive research problems at the intersection of AI and cybersecurity. Develop research directions, technical hypotheses, and experimental plans. Design and lead experiments, build prototypes, and evaluate results in collaboration with technical teams.
remote, United States$174k – $249k/yrFull TimeSenior (5+ years)
Tennessee Board of Regents
Lead analyses to understand regional workforce opportunities and employment outcomes. Develop and maintain dashboards and reports translating labor-market information into actionable resources.
remote, TN, United StatesFull TimeSenior (5+ years)
FAR.AI
Lead projects in AI safety research, focusing on detecting and preventing deception in models, mitigating risks in frontier AI, and building frameworks for rapid experimentation. Conduct adversarial evaluations and develop tooling for fine-tuning workflows.
remote, United States$225k – $350k/yrFull TimeSenior (5+ years)The Regents of the University of California on behalf of their Los Angeles Campus
Lead complex evaluation and research projects, shape research designs, and implement data collection strategies. Conduct advanced analyses and develop reporting products.
remote, United StatesFull TimeSenior (5+ years)
M3USA
Lead feasibility assessments for clinical trials, coordinating with Business Development, Site Directors, and Principal Investigators. Manage the feasibility process from intake to submission, ensuring accurate completion of questionnaires.
remote, United StatesFull TimeSenior (5+ years)
Saratoga Medical Center
Analyze behavioral and social science data, focusing on survey design, sampling, and weighting methods. Conduct advanced modeling, including multilevel and longitudinal methods, and support manuscript preparation.
remote, United StatesFull TimeSenior (5+ years)
Microsoft
Lead and conduct research into agentic transformation, shaping research approaches and combining qualitative methods to understand emerging behaviors and experiences.
remote, CA, United States$143k – $304k/yrFull TimeMiddle (2-4 years)
Worldwide Clinical Trials
Manage clinical research activities at investigative sites, ensuring compliance with regulatory standards and protocol adherence. Conduct monitoring visits, train site personnel, and support study start-up and closeout activities.
remote, United States$97k – $193k/yrFull TimeSenior (5+ years)
Humana
Design and execute outcomes studies to evaluate clinical program performance. Apply statistical and epidemiologic methods to analyze large datasets and generate evidence for decision-making.
remote, United States$104k – $143k/yrFull TimeSenior (5+ years)Integrated Business & Technical Consultants
Lead the design and execution of systematic evidence reviews, conduct causal study assessments, and develop comprehensive evidence syntheses. Mentor analytical review teams and critically review experimental and quasi-experimental impact evaluation studies.
remote, DC, United States$134k – $180k/yrFull TimeSenior (5+ years)
Columbus
Conduct scientific evaluations of R&D landscapes to identify research gaps. Monitor progress toward established metrics and develop briefings for diverse audiences. Support the development and management of R&D programs, including administrative tasks like analyzing and writing reports.
remote, United States$121k – $210k/yrFull TimeSenior (5+ years)Spectrum Brands
Lead the creation of an R&D-focused consumer science capability, focusing on product formulation, performance validation, and prototype development. Develop and manage consumer research programs, including In-Home Use Tests and product experience validation.
remote, United StatesFull TimeSenior (5+ years)Spectrum Brands
Establish and lead R&D-focused consumer science capability. Develop strategies for consumer understanding, validate product performance, and translate consumer feedback into actionable recommendations.
remote, MO, United StatesFull TimeSenior (5+ years)FAR.AI
Lead research projects on deception detection and monitoring, defining research questions, setting milestones, and assessing results. Conduct post-training experiments on large models, diagnose issues, and design model organisms.
remote, United StatesFull TimeSenior (5+ years)
RTX
Develop and implement research-grade algorithms for RF signal processing. Conduct statistical signal processing, detection techniques, and adaptive signal processing. Model RF propagation and signatures, and apply machine learning for optimal control.
remote, United States$132k – $252k/yrFull TimeLead / ManagerColumbus Technologies and Services
Conduct scientific evaluations of R&D landscapes to identify research gaps, monitor progress towards metrics, and develop briefings for diverse audiences. Support the development and management of R&D programs, including administrative tasks like analyzing and writing reports.
remote, United StatesFull TimeSenior (5+ years)
CSL
Provide expert technical assessment and scientific guidance for CMC activities in biologics, focusing on process development, analytical development, and technology transfer. Develop data-driven recommendations balancing scientific rationale and regulatory expectations.
remote, Waltham, MA, United States$179k – $212k/yrFull TimeSenior (5+ years)
A-Alpha Bio
Develop AI/ML methods for predicting and engineering protein-protein interactions. Design benchmarks to assess model performance and generate deliverables like data packages and technical reports. Contribute to the company codebase and database, ensuring effective rollout of new capabilities.
remote, United States$164k – $206k/yrFull TimeSenior (5+ years)WestEd Career
Lead mid- to large-sized research and evaluation projects, overseeing complex, multi-method studies. Manage multiple concurrent workstreams, ensuring quality and integration across teams.
remote, United States$122k – $191k/yrFull TimeLead / Manager
Amgen
Lead clinical operational strategy and execution for the Observational Research portfolio, ensuring alignment with evidence generation objectives. Develop operational plans, timelines, and budgets in collaboration with Product Teams.
remote, United States$204k – $277k/yrFull TimeDirector
Ipas
Provide technical leadership to improve quality abortion and contraception care. Develop technical tools and resources, conduct training, and support fundraising initiatives. Analyze service delivery data and issue clinical recommendations for quality improvement.
remote, AZ, United States$165k – $180k/yrFull TimeSenior (5+ years)Lifelancer
Serve as clinical scientist on late-stage clinical trials for Orexin-targeted programs. Oversee protocol development, trial execution, recruitment, and data monitoring. Act as primary liaison for Clinical Operations and manage inquiries from sites and CROs.
remote, IN, United States$153k – $268k/yrFull TimeSenior (5+ years)
SecureBio
Conduct capability and safeguard assessments of emerging AI models, executing evaluation pipelines and analyzing data to identify risks. Manually assess models for biological knowledge and willingness, synthesizing findings into evaluation reports and risk summaries.
remote, United States$235k – $300k/yrFull TimeSenior (5+ years)
ICON plc
Lead or support clinical studies, ensuring scientific execution of protocols. Act as the clinical point of contact for scientific inquiries, oversee trial design, and lead Medical Monitoring activities. Collaborate on protocol development, monitor data issues, and prepare scientific presentations.
remote, United StatesFull TimeSenior (5+ years)
Wonderlic
Lead the development of the Jobs Engine, ensuring its architecture and integrity while expanding its capabilities. Collaborate with product managers and engineers to translate scientific requirements into AI systems.
remote, United States$130k – $150k/yrFull TimeSenior (5+ years)
Troveo AI
Monitor and synthesize trends in AI and machine learning, conduct experiments with emerging models and tools, and identify opportunities to enrich existing data assets. Translate research into actionable outputs, advance a research program, and partner with product and engineering teams.
remote, United StatesFull TimeSenior (5+ years)
Airbnb
Collaborate with stakeholders to analyze people-related business problems and gather relevant data. Utilize statistical models and data science methodologies to gain insights into recruiting, hiring, and retention processes. Lead compensation analytics and design Airbnb's quality-of-hire metric.
remote, United States$180k – $210k/yrFull TimeSenior (5+ years)
Datavant
Lead the scientific delivery of agent co-development partnerships, ensuring scientific standards are embedded in workflows. Collaborate within product pods to conceptualize and evaluate scientific agents, design workflows, and conduct internal testing.
remote, United States$140k – $175k/yrFull TimeSenior (5+ years)Texas A&M University System
Oversee the Research Intelligence Platform's development and adoption. Conduct performance benchmarking and comparative analyses of research activities. Analyze research expenditures, proposals, awards, and publications.
remote, United StatesFull TimeSenior (5+ years)
Fingerprint
Conduct independent research on device-identification and bot-detection techniques in modern browsers. Own findings from initial discovery through engineering implementation, providing actionable recommendations based on data.
remote, United States$174k – $235k/yrFull TimeSenior (5+ years)
Arbor Research Collaborative for Health
Lead complex health services research projects, providing expertise to clients and health care organizations. Oversee data collection and analysis, interpret findings, and translate evidence into actionable recommendations.
remote, DC, United States$63k – $105k/yrFull TimeSenior (5+ years)
Cortek Inc
Serve as a technical expert in laboratory operations, resolving system issues and developing plans for complex systems. Manage multicenter studies and short-term testing activities, ensuring proper implementation of programs.
remote, Arlington, VA, United StatesFull TimeSenior (5+ years)
PCI GS
Provide scientific leadership and technical consultation for public health initiatives. Conduct scientific reviews, evaluate methodologies, and guide analytical approaches. Manage multiple scientific projects, ensuring scientific rigor and collaboration among experts.
remote, United StatesFull TimeSenior (5+ years)10,000,000+ more jobs available!
