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  3. Registered Nurse

Onsite Registered Nurse jobs in Missouri, USA

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Registered Nurse Jobs in Missouri — On-Site Opportunities Await

Missouri's healthcare network continues to expand, creating strong demand for skilled professionals ready to fill registered nurse on-site jobs across hospitals and clinics throughout the state. With 500+ open positions currently available, this is an excellent moment for nurses to join dedicated on-site teams delivering direct, compassionate patient care every day.

Employers across Missouri look to hire a registered nurse who combines a valid nursing license with hands-on clinical experience in acute or long-term care settings. Strong communication, quick critical thinking, and genuine compassion remain essential, especially when coordinating with physicians and families. Familiarity with electronic health records and infection control protocols further strengthens a candidate's appeal to hiring managers.

On-site registered nurse roles in Missouri typically unfold within busy hospital units, outpatient clinics, or long-term care facilities, where direct patient contact drives every shift. The state's healthcare systems continue posting new registered nurse vacancies as demand for bedside care grows alongside an aging population. This steady regional need makes Missouri a dependable market for nursing professionals seeking stability.

If you're ready to advance your nursing career, now is the time to explore registered nurse positions throughout Missouri. Global Work AI connects dedicated nurses with employers eager to welcome new talent, making it easier than ever to find the right on-site opportunity and take the next step forward.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average salary for a registered nurse in Missouri?

    In Missouri, pay for a registered nurse typically lands a bit below the national median, with many full-time roles ranging from about $65,000 to $85,000 a year depending on setting, specialty, and experience. Hospital units, ICU coverage, and charge duties can push earnings higher, while smaller clinics may pay less but offer steadier hours. St. Louis, Kansas City, and other larger markets often set the pace. Benefits, shift differentials, and overtime can also affect total compensation, so it helps to compare current openings by employer and facility type.
  • What qualifications do I need to become a registered nurse in Missouri?

    To work as a registered nurse in Missouri, candidates usually need an ADN or BSN from an accredited nursing program, successful completion of the NCLEX-RN, and an active Missouri RN license through the state board. Employers also expect CPR certification, background screening, and up-to-date immunizations in many clinical settings. Some hospitals prefer a BSN, especially for acute care or leadership tracks. New applicants may also need references and clinical experience from practicum hours, so reviewing licensure steps and program options early can save time.
  • What skills are employers looking for in a registered nurse?

    Strong bedside communication, safe medication administration, and sound clinical judgment are core expectations for a registered nurse in Missouri. Employers also look for patient assessment skills, accurate charting in electronic health record systems, teamwork, and calm decision-making under pressure. In hospital and clinic settings, adaptability matters because priorities can change quickly across shifts. Compassion, organization, and infection-control knowledge are equally important. If you are comparing roles, it helps to match your strengths with the unit culture and patient population each employer serves.
  • What are the main responsibilities of a registered nurse in a hospital or clinic?

    Day-to-day work usually centers on assessing patients, planning care, giving medications, monitoring vital signs, and communicating changes to physicians or advanced practice providers. A registered nurse in Missouri may also educate patients and families, document treatment accurately, coordinate discharge steps, and follow facility protocols for safety and infection prevention. In a hospital, responsibilities can include triage and care coordination across units; in a clinic, the pace often leans more toward routine procedures and patient education. Reading current role descriptions can show how duties differ by setting.
  • What is the hiring process for a registered nurse position?

    Most employers start with an application review, followed by interviews that may include behavioral and clinical questions. For a registered nurse role in Missouri, candidates should expect license verification, reference checks, background screening, and sometimes drug testing or skills validation. Hospital systems may also request immunization records and proof of CPR certification before extending an offer. Some organizations use panel interviews or shadowing on the unit. Preparing examples of patient care, teamwork, and handling urgent situations can make the next step clearer when comparing openings.
  • What shift schedules and work conditions are common for an on-site registered nurse role?

    On-site nursing jobs in Missouri often run on 8-, 10-, or 12-hour schedules, with many hospital positions built around days, nights, weekends, and holidays. Because patient care continues around the clock, shift differentials are common, and some units also offer rotating schedules. Work conditions can involve standing for long periods, moving between rooms, lifting with assistance, and wearing full clinical attire or PPE. Clinics are usually more predictable than inpatient units. It helps to compare schedule patterns and physical demands before choosing a role that fits your routine.
  • What career growth opportunities are available for a registered nurse in Missouri?

    Career paths for a registered nurse in Missouri often expand into charge nurse, preceptor, case management, quality improvement, or unit leadership roles. With added education or certification, nurses may move into ICU, ER, perioperative care, informatics, or advanced practice tracks such as nurse practitioner programs. Many employers value a BSN for advancement, and larger health systems may support tuition assistance or specialty training. Rural and urban facilities can offer different growth routes, so it is worth comparing openings, certification preferences, and internal promotion policies when planning the next stage.

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500+ jobs found

  • Aurora Health and Rehabiliation

    Aurora Health and Rehabiliation

    Today

    Registered nurse (rn)

    We're actively seeking skilled and motivated Registered Nurse's to join our growing family. If you're ready to make a meaningful impact, thrive in a collaborative environment, and be part of our...

    onsite, Rolla, MO, United States
    $77k – $91k/yrPart TimeJunior (<2 years)
  • Saint Luke's Health System

    Saint Luke's Health System

    a day ago

    Registered nurse - main or

    Job Description We are looking for experienced operating room nurse who work well under pressure and embrace the unexpected. We are seeking nursing professionals that are passionate about their...

    onsite, Kansas City, MO, United States
    Full TimeJunior (<2 years)
  • Phoenix Home Care and Hospice

    Phoenix Home Care and Hospice

    2 days ago

    Registered nurse (rn), hospice admissions

    Weekend Hospice Admissions RN $5,000 Sign on Bonus! Springfield, MO & surrounding areas Full Time: 30-40hrs | 10-hour Shifts | Saturday - Monday Some nurses change lives in quiet, powerful moments....

    onsite, Springfield, MO, United States
    Full TimeJunior (<2 years)
  • Saint Luke's Health System

    Saint Luke's Health System

    2 days ago

    Registered nurse - ldrp

    Job Description Are you an RN looking for an opportunity to gain experience with lots of opportunities in continuing education? Apply Now!! Saint Luke's North Hospital is looking for a talented...

    onsite, Kansas City, MO, United States
    Full TimeJunior (<2 years)
  • CoxHealth

    CoxHealth

    3 days ago

    Registered nurse - 300 w pulmonary - full time - night shift

    Facility: CoxHealth South: 3801 S National Ave, Springfield, Missouri, United States of America, 65807 Department: 1028 Pulmonary 300 W South Scheduled Weekly Hours: 36 Hours: 6:30 pm-7:00 am Work...

    onsite, Springfield, MO, United States
    Full TimeJunior (<2 years)
  • Takeda

    Takeda

    5 days ago

    Registered nurse (rn)

    By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with...

    onsite, Springfield, MO, United States
    $64k – $88k/yrFull TimeJunior (<2 years)
  • Ignite Medical Resort Kansas City Northland

    Ignite Medical Resort Kansas City Northland

    5 days ago

    Registered nurse / licensed practical nurse

    Description We are on Fire Kansas City! Ignite Medical Resort Kansas City is Hiring! If you want to work with a company who values and appreciates its employees, join Ignite Medical Resorts and help...

    onsite, Kansas City, MO, United States
    Full TimeJunior (<2 years)
  • Brio Living Services

    Brio Living Services

    5 days ago

    Quality registered nurse, rn

    Quality Registered Nurse, RN Department: Participant Care Employment Type: Full Time Location: St. Joseph, MI Reporting To: Sandi Lewis Compensation: $75,000 - $82,000 / year Description Schedule:...

    onsite, Saint Joseph, MO, United States
    $75k – $82k/yrFull TimeJunior (<2 years)
  • BJC HealthCare

    BJC HealthCare

    5 days ago

    Registered nurse (rn) - float pool (days or nights) - part time

    Additional Information About the Role Bring your experience to one of the nation's leading academic medical centers and enjoy the flexibility to create a schedule that works for you. As a Part-Time...

    onsite, St Louis, MO, United States
    $30k/yrPart TimeJunior (<2 years)
  • Mosaic Health System

    Mosaic Health System

    5 days ago

    Registered nurse - surgical and surgical step down

    The RN Inpatient works under the supervision of leadership. The RN Inpatient assesses, plans, implements, evaluates and supervises individual patient care according to standards. Accepts...

    onsite, Saint Joseph, MO, United States
    Full TimeJunior (<2 years)
  • CenterPointe Hospital Columbia

    CenterPointe Hospital Columbia

    6 days ago

    Registered nurse (rn) - part time

    Overview RN - Up to $5K Sign On Bonus available for part-time positions CenterPointe Hospital Columbia is looking for compassionate nurses to provide exceptional patient care at our 80-bed inpatient...

    onsite, Columbia, MO, United States
    $77k – $99k/yrPart TimeJunior (<2 years)
  • CoxHealth

    CoxHealth

    6 days ago

    Registered nurse - operating room - full time - evening shift

    Facility: CoxHealth South: 3801 S National Ave, Springfield, Missouri, United States of America, 65807 Department: 1056 Operating Room South Scheduled Weekly Hours: 40 Hours: 10:40 AM - 9:10 PM Work...

    onsite, Springfield, MO, United States
    Full TimeJunior (<2 years)
  • Missouri Delta Medical Center

    Missouri Delta Medical Center

    6 days ago

    Registered nurse - rn geriatric/adolescent psych (nights)

    BASIC FUNCTIONS OF POSITION: Prescribes, delegates, and coordinates nursing care for patients utilizing the nursing process. Provides leadership by working cooperatively with ancillary departments...

    onsite, Sikeston, MO, United States
    Full TimeJunior (<2 years)
  • Valley Hope Addiction Treatment & Recovery

    Valley Hope Addiction Treatment & Recovery

    7 days ago

    Rn - registered nurse ( night shift )

    Registered Nurse (Detox/Mental Health) - Night Shift 6:30pm - 7:00am Valley Hope of Boonville has an exciting opportunity for a Registered Nurse (RN) to join our dedicated and passionate team! Valley...

    onsite, Boonville, MO, United States
    $81k – $91k/yrFull TimeJunior (<2 years)
  • University of Missouri Health Care

    University of Missouri Health Care

    7 days ago

    Registered nurse (rn) - adult overflow - prn

    ABOUT THE JOB MU Health Care is looking for a compassionate and dedicated individual to join our nursing team. As a member of our team, you will play a vital role in assessing and meeting the varied...

    onsite, Columbia, MO, United States
    $73k/yrPart TimeJunior (<2 years)
  • AdamsPlace

    AdamsPlace

    8 days ago

    Registered nurse (rn)

    Registered Nurse for Osage Beach Center for Behavioral Health Nightshift (7p-7a) (3-Consecutive Nights, Flexible) Full-Time, Behavioral Health Registered Nurse (RN) Are you interested in improving...

    onsite, Osage Beach, MO, United States
    Full TimeJunior (<2 years)
  • University Health

    University Health

    8 days ago

    Registered nurse (rn) - inpatient behavioral health - ft nights (3 nights per week) - tmc

    If you are a current University Health or University Health Physicians employee and wish to be considered, you must apply via the internal career site. Please log into myWORKDAY to search for...

    onsite, Kansas City, MO, United States
    Full TimeJunior (<2 years)
  • A

    Avalon View Health and Wellness

    9 days ago

    Registered nurse (rn)

    We're actively seeking skilled and motivated Registered Nurse's to join our growing family. If you're ready to make a meaningful impact, thrive in a collaborative environment, and be part of our...

    onsite, Liberty, MO, United States
    Part TimeJunior (<2 years)
  • UHS

    UHS

    12 days ago

    Registered nurse (rn) days

    Responsibilities Three Trails Behavioral Hospital in the area of Independence, MO is actively hiring a patient centered Registered Nurse (RN) Days to join our growing behavioral health team! This...

    onsite, Independence, MO, United States
    Full TimeEntry with Degree
  • THE ARC OF THE OZARKS

    THE ARC OF THE OZARKS

    13 days ago

    Registered nurse (rn) | community-based | part time

    Job Details: Job Location: Elfindale - Springfield, MO Salary Range: $34.84 Hourly Community Registered Nurse (CRN) | Part-Time | Weekdays + occasional weekends | Springfield, MO | Starting at...

    onsite, Springfield, MO, United States
    $69k/yrPart TimeMiddle (2-4 years)
  • BJC HealthCare

    BJC HealthCare

    14 days ago

    Acute care medicine registered nurse – nights

    Additional Information About the Role The BJC RN Career Ladder differentiates BJC as the place for nurses to work in the greater St. Louis area! This is a tool to empower nurses to work at the top of...

    onsite, St Louis, MO, United States
    Full TimeEntry with Degree
  • Bethesda Health Group

    Bethesda Health Group

    15 days ago

    Registered nurse (rn)

    Bethesda Brings out the Best in Talented, Caring People! At Bethesda, more than 1,200 employees dedicate their careers to improving the lives of others. As a team member at Bethesda, you'll enjoy...

    onsite, St Louis, MO, United States
    $59k – $97k/yrPart TimeJunior (<2 years)
  • GC Asset Management LLC

    GC Asset Management LLC

    16 days ago

    Registered nurse

    About the Role: We are seeking a full-time night shift highly skilled and compassionate Registered Nurse to join our team in Lemay, MO at Bel Oak of Lemay . As a Registered Nurse, you will be...

    onsite, Lemay, MO, United States
    Full TimeJunior (<2 years)
  • BJC HealthCare

    BJC HealthCare

    16 days ago

    Registered nurse (rn) - float pool (days or nights) - prn

    Additional Information About the Role Join Barnes-Jewish Hospital, part of BJC HealthCare, as a PRN Clinical Nurse Float and expand your clinical expertise across a wide range of inpatient units. In...

    onsite, St. Louis, MO, United States
    $30k/yrPart TimeJunior (<2 years)
  • VitalCore Health Strategies

    VitalCore Health Strategies

    17 days ago

    Registered nurse (rn) for prn

    Join the VitalCore Health Strategies Team in Michigan! We're people fueled by passion, not by profit! VitalCore Health Strategies, (VCHS), an industry leader in correctional healthcare, has an...

    onsite, Saint Joseph, MO, United States
    Part TimeJunior (<2 years)
  • F

    FAMILY RESIDENTAL HOMECARE LLC

    17 days ago

    Rn (registered nurse)

    Benefits: Paid time off About the Role: Family Residential Homecare LLC is looking for a compassionate and dedicated Registered Nurse (RN) to join our growing team in Joplin, MO. This is a rewarding...

    onsite, Joplin, MO, United States
    Full TimeJunior (<2 years)
  • BAYADA Home Health Care

    BAYADA Home Health Care

    18 days ago

    Registered nurse, rn - home care

    Find Stability in Your Nursing Career at BAYADA and a $4000 Sign on Bonus for Full-time Night Nurses We just celebrated 50 years, and we plan on 50 more! BAYADA Home Health Care is a non-profit...

    onsite, Columbia, MO, United States
    Part TimeJunior (<2 years)
  • Select Specialty Hospital - St. Louis

    Select Specialty Hospital - St. Louis

    19 days ago

    Registered nurse (rn) full-time

    Overview Position: Registered Nurse (RN) Location: St. Charles, MO Schedule: Full-Time Day OR Night 7-7, every other weekend in rotation Compensation: $40.12-$54.00 per hour Competitive shift...

    onsite, Saint Charles, MO, United States
    $81k – $109k/yrFull TimeJunior (<2 years)
  • Select Specialty Hospital - St. Louis North

    Select Specialty Hospital - St. Louis North

    19 days ago

    Registered nurse (rn) prn

    Overview Position: Registered Nurse (RN) Location: Select Specialty Hospital - St. Louis North 63136 Located inside of Christian Northeast Hospital Schedule: PRN Day or Night 7-7 -PRN Requirement is...

    onsite, St. Louis, MO, United States
    $107k/yrPart TimeJunior (<2 years)
  • CoxHealth Rehabilitation Hospital

    CoxHealth Rehabilitation Hospital

    19 days ago

    Registered nurse (rn) - new graduate ft days

    Overview Hospital Name: CoxHealth Rehabilitation Hospital In Partnership with Select Medical Position: Registered Nurse (RN) – New Graduate Location: Ozark, Missouri Schedule: Full-time Days -...

    onsite, Ozark, MO, United States
    Full TimeEntry with Degree
  • CenterPointe Hospital

    CenterPointe Hospital

    19 days ago

    Registered nurse (rn) - up to $12,000 sob

    Overview CenterPointe is making great strides in Behavioral Health and we invite you to meet our new leadership team and explore your future with us! Great pay, flexibility, advancement opportunities...

    onsite, St. Charles, MO, United States
    $81k – $111k/yrFull TimeJunior (<2 years)
  • Acadia

    Acadia

    19 days ago

    Registered nurse (rn) - sign on bonus

    CenterPointe is making great strides in Behavioral Health and we invite you to meet our new leadership team and explore your future with us! Great pay, flexibility, advancement opportunities and work...

    onsite, St. Charles, MO, United States
    $81k – $111k/yrFull TimeJunior (<2 years)
  • Mosaic Life Care

    Mosaic Life Care

    19 days ago

    Registered nurse - surgical and surgical step down

    The RN Inpatient works under the supervision of leadership. The RN Inpatient assesses, plans, implements, evaluates and supervises individual patient care according to standards. Accepts...

    onsite, Saint Joseph, MO, United States
    Full TimeJunior (<2 years)
  • Missouri Delta Medical Center

    Missouri Delta Medical Center

    21 days ago

    Registered nurse (rn) - emergency department - days

    BASIC FUNCTIONS OF POSITION: Prescribes, delegates, and coordinates nursing care for patients utilizing the nursing process. Provides leadership by working cooperatively with ancillary departments...

    onsite, Sikeston, MO, United States
    Full TimeJunior (<2 years)
  • Missouri Delta Medical Center

    Missouri Delta Medical Center

    21 days ago

    Registered nurse (rn) - cardiac rehabilitation

    SUMMARY OF POSITION: Provides individualized nursing care to patients enrolled in cardiac rehabilitation, including assessment, cardiac monitoring during prescribed exercise, patient education, care...

    onsite, Sikeston, MO, United States
    Full TimeJunior (<2 years)
  • SSM Health Rehabilitation Hospital

    SSM Health Rehabilitation Hospital

    23 days ago

    Registered nurse (rn) prn tier 2

    Overview Registered Nurse (RN) - PRN Tier 2 | $57/hour | $5,000 Sign-On Bonus SSM Health Rehabilitation Hospital | A joint venture with Select Medical Location: Bridgeton, MO Rate: $57/hour PRN Tier...

    onsite, Bridgeton, MO, United States
    $115k/yrPart TimeJunior (<2 years)
  • The University of Kansas Health System

    The University of Kansas Health System

    a month ago

    Registered nurse (rn) - perioperative nurse

    Position Title Registered Nurse (RN) - Perioperative Nurse Liberty Hospital Position Summary / Career Interest: The Perioperative RN provides professional nursing care through assessment, diagnosis,...

    onsite, Liberty, MO, United States
    Full TimeJunior (<2 years)
  • Mosaic Life Care

    Mosaic Life Care

    a month ago

    Registered nurse - nicu/nursery

    The RN Inpatient works under the supervision of leadership. The RN Inpatient assesses, plans, implements, evaluates and supervises individual patient care according to standards. Accepts...

    onsite, Saint Joseph, MO, United States
    Full TimeJunior (<2 years)
  • Veterans Health Administration

    Veterans Health Administration

    a month ago

    Registered nurse (nurse manager specialty care services )

    Summary The John J. Pershing Veterans Affairs Medical Center (JJP VAMC), a Level 3 complexity facility, is recruiting a Registered Nurse to serve as the Nurse Manager for Specialty Care Services....

    onsite, Poplar Bluff, MO, United States
    $121k/yrFull TimeLead / Manager
  • NueHealth

    NueHealth

    a month ago

    Registered nurse or prn

    To act as patient advocate, providing continuity of care designed to meet individual patient needs through collaboration with other members of the healthcare team and supporting the philosophy,...

    onsite, Platte City, MO, United States
    Part TimeMiddle (2-4 years)

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