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  1. Home
  2. ›Onsite Jobs
  3. ›Maine
  4. ›Portland
  5. ›Registered Nurse

Onsite Registered Nurse jobs in Portland, Maine, USA

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  • Sun
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      Senior Product Manager Interview

      Sarah Jenkins

    • 2:30 PM - 3:00 PM

      Initial Interview

      Alex Chen

  • Mon
    • 11:00 AM - 11:15 AM

      Product Manager Interview

      David G. (Hiring Manager)

    • 4:15 PM - 5:15 PM

      First Round Interview

      Sophie L.

  • Tue
    • 1:20 PM - 1:45 PM

      Introductory Interview

      Marta W.

    • 2:30 PM - 3:00 PM

      Kick-off Interview

      Daria (HR)

  • Wed
    • 1:00 PM - 1:45 PM

      Qualifying Interview

      James Miller

    • 5:30 PM - 6:00 PM

      Discovery Interview

      Chris V.

  • Thu
    • 2:30 PM - 3:00 PM

      First Interview

      Michael T.

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Registered Nurse Jobs in Portland, Maine — On-Site Opportunities Await

Portland's growing healthcare network is actively seeking dedicated professionals to fill registered nurse jobs in Portland, with 124 open positions available for an on-site team. As patient care demands rise across the region, hospitals and clinics are looking to hire a registered nurse who can deliver compassionate, high-quality care. This is an excellent opportunity to join a thriving medical community in coastal Maine.

Successful candidates bring strong clinical assessment skills, proficiency with electronic health records, and the ability to manage multiple patients in fast-paced environments. Employers seek registered nurse candidates who communicate clearly with patients and multidisciplinary teams, demonstrate sound critical thinking during emergencies, and stay current with evolving clinical protocols. Compassion, adaptability, and attention to detail remain essential traits across every unit, from medical-surgical floors to specialty departments throughout Portland facilities.

On-site registered nurse positions in Portland typically involve rotating shifts within hospital systems, outpatient centers, or long-term care facilities, reflecting the hands-on nature of modern healthcare delivery. Maine's healthcare sector continues to expand, driven by an aging population and increased regional investment in medical infrastructure. This sustained demand creates consistent registered nurse vacancies and long-term career stability for professionals committed to on-site patient care.

If you're ready to advance your nursing career, explore current registered nurse vacancies through Global Work AI and connect with top healthcare employers in Portland. Take the next step toward a rewarding role where your skills make a real difference every day.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average salary for a registered nurse in Portland, Maine?

    In Portland, Maine, a registered nurse typically earns a wage shaped by experience, unit type, and employer setting. Local hospital roles often track near the state and metro market, with annual pay commonly landing in the mid-$70,000s to low-$90,000s for full-time staff, and higher earnings possible with nights, weekends, or specialty certifications. Benefits can also add real value, including health coverage and retirement plans. Reviewing current Portland postings is the best way to compare base pay, differentials, and sign-on incentives.
  • What qualifications and nursing license are required for a registered nurse job in Maine?

    Most employers in Maine look for an Associate Degree in Nursing or Bachelor of Science in Nursing, plus passing the NCLEX-RN. A valid Maine RN license is required, or eligibility for licensure through the Maine State Board of Nursing if you are moving from another state. Background checks, CPR certification, and immunization records are also common. Some facilities prefer recent acute-care experience, especially in Portland healthcare settings, so it helps to compare postings and note any unit-specific requirements before applying.
  • What clinical skills and bedside experience do employers look for in a registered nurse?

    Hiring teams usually value strong assessment skills, medication administration accuracy, IV therapy, wound care, and safe use of electronic health records. Just as important are communication, patient education, prioritization, and calm decision-making during changes in condition. In Portland, Maine, hospitals and outpatient sites often favor bedside experience in med-surg, telemetry, emergency, or post-op care because it shows confidence with varied patient needs. If your background is mixed, highlight measurable outcomes and the settings where you worked most independently.
  • What are the main responsibilities of a registered nurse in a hospital or healthcare facility in Portland?

    Daily work in a Portland hospital or clinic usually centers on assessing patients, developing care plans, giving medications, documenting treatment, and coordinating with physicians, therapists, and support staff. A registered nurse also monitors vital signs, responds to symptom changes, prepares discharges, and helps families understand next steps. In Maine healthcare facilities, careful charting and patient safety are essential parts of the role. Because duties can vary by unit, it is useful to compare job ads for acute care, rehab, and long-term care.
  • What shift schedules and work conditions should I expect in an on-site registered nurse role?

    On-site nursing jobs in Portland, Maine commonly include 12-hour day or night shifts, rotating schedules, weekends, holidays, and occasional on-call coverage. The pace can be busy, especially in hospitals, with a mix of standing, lifting, charting, and fast clinical decision-making. Some employers also expect float coverage across nearby units or campuses. Weather-related travel in Maine can affect commutes during winter, so many candidates weigh schedule flexibility, shift differentials, and workload expectations when reviewing openings.
  • What specialties are most in demand for registered nurses in Portland, Maine?

    Demand is often strongest in med-surg, emergency care, critical care, telemetry, perioperative services, and behavioral health, with additional need in rehab and long-term care. Portland’s larger healthcare employers also look for nurses with experience in pediatrics, oncology, and home health depending on current patient volume. Specialties tied to aging populations can be especially relevant across Maine. If you are considering a move or advancement, compare openings by unit type and note which certifications are most often requested.
  • What should I know about working as a registered nurse in Maine healthcare settings, including patient ratios and state regulations?

    Maine does not set a universal statutory nurse-to-patient ratio for every setting, so assignments usually depend on acuity, unit policy, and staffing needs. That makes it important to ask about typical ratios, support staff, and escalation procedures in Portland facilities. Maine follows state board rules for RN practice, licensure, delegation, and scope, while hospitals often maintain strict documentation and patient safety standards. Understanding these expectations early can help you compare employers and choose a setting that matches your workload comfort.

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124 jobs found

  • CFG HEALTH SYSTEM LLC

    CFG HEALTH SYSTEM LLC

    a day ago

    Registered nurse - $4,000 sign on bonus!

    Job Details: Job Location: Cumberland County Jail - ME - Portland, ME Position Type: Full Time Salary Range: $50.00 - $50.00 Hourly Job Shift: Night Position Summary Registered Nurses (RNs) provide...

    onsite, Portland, ME, United States
    $101k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    2 days ago

    Clinical nurse (rn) - continuing care nicu (ccn)

    Barbara Bush Children’s Hospital Nursing Req #: 97991 This is a bargaining unit position Job Posting Date: 10/27/2026 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    2 days ago

    Clinical nurse (rn) - general medical and transitional care unit (r7)

    Maine Medical Center Nursing Req #: 98227 This is a Bargaining Unit Position Date Posted: 10/27/2026 This is a Clinical Nurse II vacancy open to RNs with at least one year of RN work experience. We...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    2 days ago

    Clinical nurse (rn) - inpatient float pool - new graduates welcome

    Maine Medical Center Nursing Req #: 93169 This is a Clinical Nurse I vacancy open to candidates with 0 – 1 year of RN work experience. This is a bargaining unit position with 6 Positions Available....

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    2 days ago

    Clinical nurse (rn) - neurosurgical/trauma/medical surgical unit (r6)

    Maine Medical Center Nursing Req #: 98226 This is a bargaining unit position Job Posting Date: 10/27/2026 This is a Clinical Nurse II vacancy open to RNs with at least one year of RN work experience....

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    3 days ago

    Clinical nurse (rn) - certified wound ostomy continence nurse

    Clinical Nurse (RN) - Certified Wound Ostomy Continence Nurse Maine Medical Center Nursing Req #: 62267 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work...

    onsite, Portland, ME, United States
    $93k – $138k/yrFull TimeMiddle (2-4 years)
  • UnitedHealth Group

    UnitedHealth Group

    3 days ago

    Registered nurse, home health - greater casco, yarmouth, falmouth

    Explore opportunities with Amedisys, part of the Optum family of businesses. We provide home health, hospice and community-based services that help people receive quality care where they feel most...

    onsite, Portland, ME, United States
    $75k/yrFull TimeJunior (<2 years)
  • UnitedHealth Group

    UnitedHealth Group

    3 days ago

    Registered nurse, home health - auburn area portland

    Explore opportunities with Amedisys, part of the Optum family of businesses. We provide home health, hospice and community-based services that help people receive quality care where they feel most...

    onsite, Portland, ME, United States
    $75k/yrFull TimeJunior (<2 years)
  • InterMed, P.A.

    InterMed, P.A.

    4 days ago

    Registered nurse cardiology

    SUMMARY: The ambulatory care Registered Nurse (RN) is responsible for providing comprehensive care management in outpatient settings, including both primary and specialty care. To ensure a strong...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • InterMed, P.A.

    InterMed, P.A.

    4 days ago

    Registered nurse internal medicine

    SUMMARY: The ambulatory care Registered Nurse (RN) is responsible for providing comprehensive care management in outpatient settings, including both primary and specialty care. To ensure a strong...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    7 days ago

    Clinical nurse (rn) - medical surgical telemetry/imc (r9)

    Maine Medical Center Nursing Req #: 98269 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This is a bargaining unit position. Job Posting Date:...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    7 days ago

    Clinical nurse (rn) - medical intensive care unit

    Maine Medical Center Nursing Req #: 97881 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This is a Bargaining Unit position. 2 Positions...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • InterMed, P.A.

    InterMed, P.A.

    7 days ago

    Registered nurse - ambulatory surgery center

    ESSENTIAL FUNCTIONS Patient assessment is continuous and is documented on the Operating Room record according to policy. Nursing interventions are prioritized to provide optimum patient outcomes....

    onsite, Portland, ME, United States
    Part TimeJunior (<2 years)
  • Bayside Comprehensive Treatment Center

    Bayside Comprehensive Treatment Center

    7 days ago

    Lpn dispensing nurse - prn

    Overview Outpatient MAT Opioid Treatment Program (OTP) Seeking: LPN Dispensing Nurse Per Diem Hours: Working on an as-needed basis. Monday - Friday, 4:30 AM - 12:00 PM Saturday, 5:30 AM - 12:00 PM...

    onsite, Portland, ME, United States
    $48k – $60k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - medical surgical unit (p4c) - new graduates welcome

    Maine Medical Center Nursing Req #: 87096 This is a bargaining unit position. Job Posting Date: 9/2/2026 This is a Clinical Nurse I vacancy open to candidates with 0-1 year of RN work experience....

    onsite, Portland, ME, United States
    $77k/yrPart TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn)- cardiology/cardiac surgery (r1) new graduates welcome

    Maine Medical Center Nursing Req #: 95884 This is a Clinical Nurse I vacancy open to candidates with 0 – 1 year of RN work experience. This is a bargaining unit position. 5 Positions Available. Date...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Care manager (rn) - discharge planning

    Care Manager (RN) - Discharge Planning Maine Medical Center Nursing Req #: 96462 This is a Bargaining Unit Position Job Posting Date: 6/9/2026 Summary: The purpose of the Case Manager I position is...

    onsite, Portland, ME, United States
    $86k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - general surgical unit (p3cd) - new graduates welcome

    Maine Medical Center Nursing Req #: 94362 This is a bargaining unit position. Job Posting Date: 9/21/2026 2 Positions available This is a Clinical Nurse I vacancy open to candidates with 0 – 1 year...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - imc/respiratory telemetry unit (bean 5)

    Nursing Req #: 92006 This is a bargaining unit position Job posting date: 10/19/2026 2 Positions available This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - operating room - gyn/gu

    Maine Medical Center Nursing Req #: 97147 This is a Bargaining Unit Position Job Posting Date: 10/12/2026 Full Time/Days (This position will support GYN/GU) This is a Clinical Nurse 2 vacancy open to...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse educator (rn) - $20k sign-on bonus

    MaineHealth Corporate Professional - Clinical Req #: 86864 Full Time/Days This position requires schedule flexibility and could require day, evening and weekend commitments based on school/unit...

    onsite, Portland, ME, United States
    $97k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) – inpatient float pool

    Maine Medical Center Nursing Req #: 87461 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This is a bargaining unit position. Job Posting Date:...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse ii - mmcp (u)

    Clinical Nurse II - MMCP (U) Maine Medical Center Nursing Req #: 1401 Summary: The Clinical Nurse supports Maine Medical Center's mission, vision, and values by exhibiting the following behaviors:...

    onsite, Portland, ME, United States
    Full TimeMiddle (2-4 years)
  • N

    Northern Light Health

    8 days ago

    Clinical care coord/rn - cardiology - part time

    The compensation range listed reflects the range Northern Light Health anticipates relying on in setting the wages for the position. The range may not necessarily include all additional compensation...

    onsite, Portland, ME, United States
    $79k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn)- cardiology/cardiac surgery (r1)

    Clinical Nurse (RN) - Cardiology/Cardiac Surgery Maine Medical Center Nursing Req #: 94706 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This...

    onsite, Portland, ME, United States
    $83k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - operating room - orthopedics

    Maine Medical Center Nursing Req #: 96717 This is a Bargaining Unit Position Job Posting Date: 10/12/2026 2 Positions Available Full Time/Days (40 hours per week) This position will support the...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - inpatient nephrology/urology medical unit (r5)

    Maine Medical Center Nursing Req #: 87431 This is a bargaining unit position. Job Posting Date: 8/11/2026 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - neurosurgical/trauma/medical surgical unit (r6) - new graduates welcome

    Maine Medical Center Nursing Req #: 91649 This is a Bargaining Unit Position Job Posting Date: 9/2/2026 4 Positions available R6 is a dynamic 24-bed neurosurgical / trauma unit with an embedded 9-bed...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse i - mmcp (u)

    Maine Medical Center Nursing Req #: 598 Summary : The Clinical Nurse supports Maine Medical Center's mission, vision, and values by exhibiting the following behaviors: excellence, competence,...

    onsite, Portland, ME, United States
    Full TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - operating room - general surgery

    Maine Medical Center Nursing Req #: 88565 This is a Bargaining Unit Position Job Posting Date: 10/13/2026 Full Time/Days (This position will support General, ACS, Robotic, and Thoracic Surgery) This...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse manager (rn) - neonatal intensive care unit (nicu)

    Nurse Manager (RN) - Neonatal Intensive Care Unit (NICU) Barbara Bush Children’s Hospital Management/Leadership Req #: 83442 Full Time Evenings Maine Medical Center is the state’s largest medical...

    onsite, Portland, ME, United States
    $132k – $179k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse manager (rn) - inpatient medical psychiatry (p6)

    Maine Medical Center Management/Leadership Req #: 93621 Seeking a leader to oversee a 21-bed Inpatient Medical Psychiatry unit caring for a medically complex patient population, with a strong focus...

    onsite, Portland, ME, United States
    $132k – $179k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - imc/general surgical unit (r3)

    Nursing Req #: 91426 This is a bargaining unit position. Job Posting Date: 8/27/2026 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. R3 is a...

    onsite, Portland, ME, United States
    $83k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - surgical intensive care unit (scu3)

    Maine Medical Center Nursing Req #: 369 This is a Bargaining Unit Position Job Posting Date: 8/19/2024 7 Positions Available For a limited time MaineHealth is offering up to $10,000 Sign on bonus for...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - imc/respiratory telemetry unit (bean 5) - new graduates welcome

    Maine Medical Center Nursing Req #: 92318 This is a bargaining unit position Job Posting Date: 10/16/2026 5 Positions available This is a Clinical Nurse I vacancy open to candidates with 0 – 1 year...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - inpatient psychiatry (p6)

    Maine Medical Center Nursing Req #: 90187 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This is a bargaining unit position. Date posted:...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • Amedisys, Inc.

    Amedisys, Inc.

    14 days ago

    Rn case manager

    Overview Full-time days Make a difference every day as an Amedisys registered nurse case manager. Join Amedisys-one of the largest and most trusted home health and hospice companies in the U.S.-where...

    onsite, Portland, ME, United States
    $79k – $98k/yrFull TimeJunior (<2 years)
  • The Vascular Care Group

    The Vascular Care Group

    15 days ago

    Procedural nurse (portland) (per diem)

    Overview This role is responsible for providing nursing services in a vascular Office-Based Lab setting. The Cath Lab (otherwise known as Office-Based Lab) Nurse will collaborate with clinical...

    onsite, Portland, ME, United States
    $81k/yrPart TimeJunior (<2 years)
  • IU Health

    IU Health

    24 days ago

    Registered nurse-behavioral health-ambulatory

    We are seeking an individual with a minimum of one year of RN experience for this role. If you are an upcoming nurse graduate or recent nurse graduate, please apply through our pipeline requisition...

    onsite, Portland, ME, United States
    Part TimeJunior (<2 years)
  • CFG HEALTH SYSTEM LLC

    CFG HEALTH SYSTEM LLC

    25 days ago

    Registered nurse

    Job Details: Job Location: Cumberland County Jail - ME - Portland, ME Position Type: Full Time Salary Range: Undisclosed Job Shift: Night JOB SUMMARY Utilizes the nursing process to meet a variety of...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)

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