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  2. California
  3. San Diego
  4. Registered Nurse

Onsite Registered Nurse jobs in San Diego, California, USA

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      Sarah Jenkins

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      Alex Chen

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      David G. (Hiring Manager)

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      Marta W.

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      Daria (HR)

  • Wed
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      James Miller

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      Chris V.

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Registered Nurse Jobs in San Diego — On-Site Opportunities Await

San Diego's healthcare sector continues to expand, creating steady demand for registered nurse jobs in San Diego across hospitals, clinics, and specialty care centers. This on-site position offers 297 open positions for dedicated professionals ready to make a direct impact on patient care. With a growing population and expanding medical facilities, the city presents strong opportunities for nurses seeking stable, rewarding careers.

Successful candidates typically bring strong clinical assessment skills, compassionate bedside manner, and the ability to collaborate effectively within multidisciplinary teams. Proficiency in electronic health records, medication administration, and patient education is essential, along with sound judgment under pressure. Employers often seek registered nurse positions filled by candidates who demonstrate adaptability across diverse patient populations, strong communication, and a commitment to continuous learning in evolving medical practices.

On-site registered nurse roles in San Diego typically involve direct patient interaction, hands-on procedures, and close coordination with physicians and support staff within hospital or clinical settings. The region's robust healthcare infrastructure, including major medical centers and research institutions, fuels consistent hiring outlook for nursing talent. Facilities throughout the area are eager to hire a registered nurse who can thrive in fast-paced, patient-centered environments.

If you're ready to advance your nursing career in a vibrant coastal city, explore current registered nurse vacancies curated by Global Work AI. Our platform connects dedicated healthcare professionals with facilities that value skill, compassion, and commitment. Take the next step toward a fulfilling role where your expertise truly matters.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average registered nurse salary in San Diego?

    Pay for a registered nurse in San Diego, California typically sits above the national average because of the region’s cost of living and strong hospital demand. Recent market data often places hourly wages in the low-to-mid $50s, with annual earnings commonly landing around $100,000 to $120,000, depending on specialty, years in practice, and facility type. Large health systems, union contracts, and shift differentials can all affect offers. It helps to compare current postings and hospital pay bands, since compensation can vary by unit and schedule.
  • What qualifications and California RN license are required for a registered nurse job?

    Most employers in San Diego expect an active California RN license, usually supported by an Associate Degree in Nursing or a BSN from an accredited program. New graduates must pass the NCLEX-RN and complete the California Board of Registered Nursing licensing process, which may include background review and fingerprinting. Many hospitals also ask for current BLS certification, and some units prefer ACLS or PALS. Because facility standards differ, it is useful to review each posting closely and match your credentials to the setting.
  • What clinical skills and patient care experience do employers look for in a registered nurse?

    Hiring teams look for strong bedside judgment, medication administration accuracy, and comfort with electronic health records. In San Diego healthcare settings, experience with patient assessment, care planning, wound care, IV therapy, and discharge education is often valued. Employers also want clear communication, teamwork, and the ability to respond quickly to changing conditions. Acute care, telemetry, med-surg, ICU, ER, or post-op exposure can strengthen a candidacy. If you are comparing openings, notice which clinical competencies are listed most often and align them with your background.
  • What are the main responsibilities of a registered nurse in a hospital or healthcare setting?

    Daily duties usually center on assessing patients, administering medications, monitoring vital signs, and coordinating care with physicians and other clinicians. A registered nurse also documents changes in condition, teaches patients and families, and helps implement treatment plans in a hospital or clinic. In California facilities, safe staffing, infection control, and regulatory compliance are especially important. Depending on the unit, responsibilities may include IV starts, admissions, transfers, or discharge preparation. Reviewing a specific department’s workflow can help you understand how the role differs from one service line to another.
  • What shifts, weekends, and on-site work conditions should I expect as a registered nurse in San Diego?

    Most on-site registered nurse roles in San Diego run on rotating schedules that may include 12-hour shifts, nights, weekends, and holidays. Hospital-based positions often require flexibility, since patient care continues around the clock. Some departments offer self-scheduling or fixed patterns, but coverage needs can change with census and acuity. Expect standing, walking, lifting, and frequent interaction with patients and families throughout the shift. Because local facilities vary, it is smart to compare schedule details, weekend rotation rules, and unit expectations before choosing between openings.
  • How does the hiring process work for registered nurse jobs?

    The process usually starts with an application and resume review, followed by a recruiter screen or hiring manager interview. For registered nurse jobs in California, candidates may then complete reference checks, skills verification, and credential review for licensure, certifications, and immunizations. Many San Diego hospitals also use panel interviews or unit-based conversations to assess fit. Some employers require pre-employment health screening, background checks, and drug testing before an offer is finalized. If you are applying, it helps to prepare examples from recent patient care experience and review the unit’s priorities in advance.
  • What career growth opportunities are available for a registered nurse in California healthcare facilities?

    Career paths in California healthcare can expand into charge nurse, preceptor, case management, quality improvement, informatics, or specialty certification roles. In San Diego, a registered nurse may also move into higher-acuity units such as ICU, emergency, labor and delivery, or perioperative care after building experience. Many facilities support continuing education, BSN advancement, and leadership development, especially for staff who want long-term growth. Those interested in progression should compare employers that fund certification or tuition assistance, since benefits can make a meaningful difference over time.

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297 jobs found

  • Classic Residence Management LP

    Classic Residence Management LP

    Today

    Wellness center nurse - rn

    Overview Vi is recognized as a Great Place to Work and one of Glassdoor's 100 Best Companies to work for. Learn from the best and accelerate your career with Vi. What We Offer: Competitive pay...

    onsite, San Diego, CA, United States
    $100k – $111k/yrFull TimeMiddle (2-4 years)
  • Sharp HealthCare

    Sharp HealthCare

    Today

    Clinical nurse rn - float pool med-surg - pcu - short stay observation - physical acute rehab units - sharp metro campus - day – ft

    Hours: Shift Start Time: Shift End Time: AWS Hours Requirement: Additional Shift Information: Weekend Requirements: On-Call Required: No Hourly Pay Range (Minimum - Midpoint - Maximum): $64.210 -...

    onsite, San Diego, CA, United States
    $129k – $189k/yrPart TimeJunior (<2 years)
  • SCA Health

    SCA Health

    Today

    Registered nurse preop pacu ii - la jolla orthopedic

    Overview At SCA Health, we believe health care is about people – the patients we serve, the physicians we support and the teammates who push us forward. Behind every successful facility, procedure or...

    onsite, San Diego, CA, United States
    $101k – $111k/yrFull TimeJunior (<2 years)
  • Seaport Scripps Home Health

    Seaport Scripps Home Health

    a day ago

    Registered nurse clinical manager - home health

    Registered Nurse Clinical Manager - Home Health Pay Range: $120,000 - $145,000 annually Job Type: Full Time Join the Seaport Scripps Home Health Family! At Seaport Scripps Home Health, a Scripps...

    onsite, San Diego, CA, United States
    $120k – $145k/yrFull TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    2 days ago

    Clinical nurse - rn - women's recovery (pacu) - sharp mary birch - night shift - full-time 0.9 fte

    Hours: Shift Start Time: 7 PM Shift End Time: 7:30 AM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Weekend Requirements: As Needed On-Call Required: Yes Hourly Pay Range...

    onsite, San Diego, CA, United States
    $129k – $189k/yrFull TimeJunior (<2 years)
  • Scripps Health

    Scripps Health

    5 days ago

    Rn - med surg / tele - system wide resource team - varied shifts

    Schedule: 72 hours per 2-week pay period | 12-hour Varied Shifts (including weekends) Location: Float between all five Hospitals This position is eligible for New Hire Incentives Our Scripps...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • NVISION Eye Centers

    NVISION Eye Centers

    5 days ago

    Surgery center administrator | registered nurse

    Overview NVISION® Eye Centers is one of the largest ophthalmology providers in the U.S., with over 100 centers across five states including California, Oregon, Arizona, Texas, and Utah. An innovative...

    onsite, San Diego, CA, United States
    $145k – $165k/yrFull TimeLead / Manager
  • Sharp HealthCare

    Sharp HealthCare

    5 days ago

    Clinical nurse rn - oncology 1w - sharp memorial hospital - night - ft

    Hours: Shift Start Time: 7 PM Shift End Time: 7:30 AM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Weekend Requirements: Every Other On-Call Required: No Hourly Pay...

    onsite, San Diego, CA, United States
    $129k – $189k/yrFull TimeJunior (<2 years)
  • Vantage Search Group

    Vantage Search Group

    5 days ago

    Registered nurse - emergency room (prn) 5394

    We have a new need for a Registered Nurse - Emergency Room at the Naval Medical Center in San Diego, CA. Job Specific Details and Tasks: The duties for the RN include but are not limited to the...

    onsite, San Diego, CA, United States
    $157k – $177k/yrFull TimeMiddle (2-4 years)
  • Aurora San Diego

    Aurora San Diego

    5 days ago

    Registered nurse educator (full time)

    As Nurse Educator/Infection Control, this position is responsible for organizing, evaluating, and training employees and directors to improve practice competency and patient outcome. At the same...

    onsite, San Diego, CA, United States
    $107k – $121k/yrFull TimeLead / Manager
  • Lorian Health

    Lorian Health

    6 days ago

    Home health registered nurse clinical manager - rncm

    Join a Team That Makes a Difference For more than 20 years, Lorian Health has been a trusted leader in home health care, delivering compassionate, patient-centered care that enhances quality of life...

    onsite, San Diego, CA, United States
    $135k – $145k/yrFull TimeJunior (<2 years)
  • ERP International

    ERP International

    6 days ago

    Registered nurse - emergency room (prn days)

    Overview ERP International, LLC is seeking a Emergency Room Registered Nurse for a PRN position supporting the Naval Medical Center San Diego, CA. Be the Best! Join our team of exceptional health...

    onsite, San Diego, CA, United States
    $157k – $177k/yrPart TimeMiddle (2-4 years)
  • PREMIER AMBULANCE

    PREMIER AMBULANCE

    7 days ago

    Cct registered nurse

    Job Details: Level: Experienced Job Location: San Diego - San Diego, CA Position Type: Full-Time/Part-Time Salary Range: $100000.00 - $150000.00 Salary/year Job Shift: Any Premier Ambulance is...

    onsite, San Diego, CA, United States
    $100k/yrFull TimeJunior (<2 years)
  • San Ysidro Health

    San Ysidro Health

    7 days ago

    Registered nurse

    Position Summary: Under direct supervision and within established scope of practice, the Ambulatory Care Registered Nurse ensures the delivery of patient-centered services as directed by San Ysidro...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Lorian Health

    Lorian Health

    8 days ago

    Hospice (registered nurse) rn

    Join a Team That Makes a Difference For more than 20 years, Lorian Health has been a trusted leader in home health care, delivering compassionate, patient-centered care that enhances quality of life...

    onsite, San Diego, CA, United States
    $107k/yrFull TimeJunior (<2 years)
  • SCA Health

    SCA Health

    8 days ago

    Registered nurse endoscopy ii, part-time - san diego endoscopy center

    Overview At SCA Health, we believe health care is about people – the patients we serve, the physicians we support and the teammates who push us forward. Behind every successful facility, procedure or...

    onsite, San Diego, CA, United States
    $95k – $101k/yrPart TimeJunior (<2 years)
  • SCA Health

    SCA Health

    8 days ago

    Registered nurse endoscopy ii - san diego endoscopy center

    Overview At SCA Health, we believe health care is about people – the patients we serve, the physicians we support and the teammates who push us forward. Behind every successful facility, procedure or...

    onsite, San Diego, CA, United States
    $95k – $101k/yrFull TimeJunior (<2 years)
  • Scripps Health

    Scripps Health

    9 days ago

    Rn - medical acute - green hospital - nights

    This is a benefit-eligible, full-time position (72 hours every two weeks), working 12-hour Night shift Elevate your career with Scripps Health, where Compassion Meets Excellence. Invest, Empower &...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Cheer Home Care

    Cheer Home Care

    9 days ago

    Part-time concierge rn nurse care manager

    About Us We are a premier concierge private nursing in-home company dedicated to delivering bespoke, elevated care to private-pay clients. We believe that exceptional client care starts with...

    onsite, San Diego, CA, United States
    $121k – $141k/yrPart TimeMiddle (2-4 years)
  • Neighborhood House Association

    Neighborhood House Association

    9 days ago

    Registered nurse manager - bpsr

    Career Opportunities with Neighborhood House Association About NHA: The Neighborhood House Association is a non-profit organization. Head Start positions are funded in whole or in part by money...

    onsite, San Diego, CA, United States
    Full TimeMiddle (2-4 years)
  • Scripps Health

    Scripps Health

    9 days ago

    Rn - med surg / tele - system wide resource team - night shifts

    Schedule: 72 hours per 2-week pay period | 12-hour Night Shifts (including weekends) Location: Float between all five Hospitals This position is eligible for New Hire Incentives Our Scripps...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Gary and Mary West PACE

    Gary and Mary West PACE

    9 days ago

    Pace registered nurse - triage

    Join the Team Voted Best Place to Work in North County! Why Work for Gary and Mary West PACE? Because you're looking for more than just a job - you want work/life balance and the opportunity to make...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Pennant Group

    Pennant Group

    10 days ago

    Registered nurse clinical manager - home health

    Registered Nurse Clinical Manager - Home Health Pay Range: $120,000 - $145,000 annually Job Type: Full Time Join the Seaport Scripps Home Health Family! At Seaport Scripps Home Health, a Scripps...

    onsite, San Diego, CA, United States
    $120k – $145k/yrFull TimeJunior (<2 years)
  • Fresenius Medical Care

    Fresenius Medical Care

    10 days ago

    Registered nurse - rn - dialysis

    Paid one on one training and education provided Empower, engage and train dialysis patients on peritoneal and home hemodialysis using state of the art training programs and equipment Primarily works...

    onsite, San Diego, CA, United States
    $71k/yrFull TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    14 days ago

    Clinical nurse rn bu - surgery - sharp memorial hospital - evening shift - full time - eligible for new hire relocation incentive

    Hours: Shift Start Time: 10:30 AM Shift End Time: 11 PM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Holiday Requirements Weekend Requirements: Every Other On-Call...

    onsite, San Diego, CA, United States
    $129k – $189k/yrFull TimeJunior (<2 years)
  • Family Health Centers of San Diego

    Family Health Centers of San Diego

    14 days ago

    Registered nurse, pace enrollment

    For more than 55 years, Family Health Centers of San Diego’s (FHCSD) mission has been to provide caring, affordable, high-quality health care and supportive services to everyone, with a special...

    onsite, San Diego, CA, United States
    $101k/yrFull TimeJunior (<2 years)
  • The Arc of San Diego

    The Arc of San Diego

    14 days ago

    Registered nurse (mon-fri 9a-5:30p)

    Join Our Passionate Team at The Arc of San Diego! Are you ready to make a real difference in the lives of children and adults with disabilities? At The Arc of San Diego, we are the largest and most...

    onsite, San Diego, CA, United States
    $95k – $105k/yrFull TimeJunior (<2 years)
  • Lorian Health

    Lorian Health

    16 days ago

    Home health rn (registered nurse)

    Join a Team That Makes a Difference For over 20 years, Lorian Health has been a trusted leader in home health care, dedicated to enhancing patients’ quality of life and supporting their independence....

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    17 days ago

    Clinical nurse rn - 4west trauma/neuro/head & neck - sharp memorial hospital - night shift - full-time

    Hours: Shift Start Time: 7 PM Shift End Time: 7:30 AM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Weekend Requirements: Every Other On-Call Required: No Hourly Pay...

    onsite, San Diego, CA, United States
    $129k – $189k/yrFull TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    17 days ago

    Clinical nurse rn - 5west icu step-down transplant unit - sharp memorial hospital - night - full time

    Hours: Shift Start Time: 7 PM Shift End Time: 7:30 AM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Weekend Requirements: Every Other On-Call Required: No Hourly Pay...

    onsite, San Diego, CA, United States
    $129k – $189k/yrFull TimeJunior (<2 years)
  • St. Paul's Senior Services

    St. Paul's Senior Services

    19 days ago

    Rn clinic supervisor

    San Diego’s St. Paul's PACE program (Program of All-Inclusive Care for the Elderly). This innovative program is for individuals 55 years or older, who are living with chronic illness, or disabilities...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    20 days ago

    Clinical nurse rn bu - outpatient surgery - james s. brown pavilion - day shift - full time

    Hours: Shift Start Time: 6:30 AM Shift End Time: 5 PM AWS Hours Requirement: 10/40 - 10 Hour Shift Additional Shift Information: Weekend Requirements: As Needed On-Call Required: Yes Hourly Pay Range...

    onsite, San Diego, CA, United States
    $124k – $182k/yrFull TimeJunior (<2 years)
  • Apreva Hospice

    Apreva Hospice

    20 days ago

    Registered nurse hospice

    Our Company Apreva Hospice Overview Office Location: Coverage area: Schedule: Are you a Registered Nurse looking for a new opportunity? ENTER LINE OF BUSINESS is seeking a passionate, dedicated...

    onsite, San Diego, CA, United States
    $101k – $111k/yrFull TimeJunior (<2 years)
  • San Ysidro Health

    San Ysidro Health

    21 days ago

    Supervisor registered nurse

    Position Summary: Under the direction of the Ambulatory Care Manager, the Ambulatory Care Supervisor oversees the daily clinical operations, and patient care activities of assigned care teams. Within...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • McAlister Institute

    McAlister Institute

    21 days ago

    Registered nurse

    Join McAlister Institute, a 49-year beacon in San Diego's Recovery Community. The Recovery and Bridge Center’s Sobering Services is seeking a dedicated Registered Nurse to join our team. Reporting...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    22 days ago

    Registered nurse - full time days

    Kindred Hospital San Diego is a 70-bed long-term acute care hospital offering the same in-depth care you would receive in a traditional hospital, but for an extended recovery period. We partner with...

    onsite, San Diego, CA, United States
    $84k – $103k/yrFull TimeJunior (<2 years)
  • CenterWell

    CenterWell

    24 days ago

    Home health rn branch director

    Become a part of our caring community Reports To: Market Executive of Operations FLSA: Exempt Position Type: On-site at CWHH San Diego, CA branch location Work Schedule: Full-time/40 Hours The Branch...

    onsite, San Diego, CA, United States
    $126k – $173k/yrFull TimeDirector
  • Sharp HealthCare

    Sharp HealthCare

    a month ago

    Clinical nurse bu - labor and delivery - sharp mary birch - night shift - full-time 0.9 fte

    Hours: Shift Start Time: 7 PM Shift End Time: 7:30 AM AWS Hours Requirement: 12/36 - 12 Hour Shift Additional Shift Information: Weekend Requirements: As Needed On-Call Required: No Hourly Pay Range...

    onsite, San Diego, CA, United States
    $124k – $182k/yrFull TimeJunior (<2 years)
  • Excelin Health Services

    Excelin Health Services

    a month ago

    Rn branch clinical manager

    Job Summary: The Branch/Clinical Manager is responsible for the planning, coordination, and management of all financial, and clinical operation activities and programs for their Branch. The...

    onsite, San Diego, CA, United States
    Full TimeLead / Manager
  • Veterans Health Administration

    Veterans Health Administration

    a month ago

    Nurse manager - ambulatory surgery unit (asu), post anesthesia care unit (pacu)

    Summary The Ambulatory Surgery Unit (ASU), Post Anesthesia Care Unit (ASU), Nursing Interventional Radiology (IR) Cardiac Catheterization and Electrophysiology (Cath/EP) Lab Registered Nurse Manager...

    onsite, San Diego, CA, United States
    $153k/yrFull TimeMiddle (2-4 years)

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