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  1. Home
  2. ›Onsite Jobs
  3. ›Maine
  4. ›Portland
  5. ›Nurse Practitioner

Onsite Nurse Practitioner jobs in Portland, Maine, USA

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  • Sun
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      Sarah Jenkins

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      Alex Chen

  • Mon
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      David G. (Hiring Manager)

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      Chris V.

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Nurse Practitioner Jobs in Portland — On-Site Roles Shaping Local Care

Healthcare employers across Maine are actively hiring to fill 117 open positions, reflecting steady growth in community-based care. Portland's hospitals and clinics continue expanding their teams, creating fresh nurse practitioner vacancies for professionals ready to work on-site and make an immediate impact on patient care.

Employers typically look for strong clinical judgment, clear communication, and the ability to manage diverse patient populations independently. Proficiency in diagnosing and treating acute and chronic conditions, along with comfort using electronic health records, remains essential. Those exploring nurse practitioner positions should highlight adaptability, collaboration skills, and a commitment to patient-centered care.

On-site work remains the standard for this profession in Portland, where direct patient interaction is essential to quality care. Local health systems and private practices continue to hire a nurse practitioner for full-time, in-person roles supporting community wellness. Maine's growing population of older adults keeps long-term demand strong for experienced clinicians in this field.

If you're ready to advance your career while making a tangible difference in patients' lives, now is the time to explore nurse practitioner jobs in Portland. Global Work AI connects dedicated professionals with employers eager to welcome new talent. Discover opportunities that match your skills and ambitions today.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average nurse practitioner salary in Portland, Maine, and what factors affect pay?

    In Portland, Maine, a nurse practitioner can expect pay that often falls in the low-to-mid six figures annually, with variation based on specialty, years of practice, employer type, and shift schedule. Compensation in Maine is influenced by local demand, cost of living, and whether the role sits in primary care, urgent care, or a hospital-based service line. Certifications, leadership duties, and after-hours coverage can also raise earnings. Review current Portland postings and salary ranges to see how benefits, bonuses, and call expectations change the total package.
  • What qualifications, licenses, and certifications are required for a nurse practitioner job in Maine?

    Most employers in Maine expect an active RN license, completion of an accredited graduate NP program, and national board certification in the nurse practitioner population focus, such as family, adult-gerontology, or pediatrics. For practice in Portland, candidates also need Maine APRN authorization and prescriptive authority when medications are part of the role. DEA registration may be required for controlled substances. Some healthcare systems favor BLS or ACLS, plus state-specific documentation and quality training. Comparing current job ads can help clarify which credentials are mandatory versus preferred.
  • What skills do employers look for in a nurse practitioner?

    Strong clinical judgment matters, but so do communication, documentation accuracy, and the ability to build trust with patients and care teams. In Portland, Maine, employers often value experience with EHR systems, evidence-based decision-making, medication management, and patient education across age groups. Time management, triage thinking, and comfort working independently in an on-site clinical setting are also important. Because many practices coordinate closely with physicians, nurses, and specialists, teamwork remains essential. Looking at related healthcare roles can reveal which soft skills show up most often in local postings.
  • What are the main responsibilities of a nurse practitioner in an on-site clinical setting?

    Day to day, this role usually includes assessing patients, ordering and interpreting tests, diagnosing conditions, prescribing treatment, and tracking progress over time. In a Portland, Maine clinic or hospital setting, a nurse practitioner may also handle preventive care, chronic disease management, referrals, and patient counseling. Depending on the department, responsibilities can extend to same-day visits, procedure support, and coordination with physicians or specialists. Accurate charting and compliance with state practice rules are central. Checking current on-site listings can show how duties differ between primary care, urgent care, and specialty teams.
  • What does the hiring process typically look like for a nurse practitioner job in Portland, Maine?

    The process usually begins with an application and resume review, followed by screening for licensure, board certification, and fit with the clinical team. In Portland, Maine, candidates often move through one or more interviews, sometimes including a recruiter call, a manager meeting, and a panel with physicians or advanced practice staff. Employers may ask for references, background checks, and proof of immunizations or credentials before making an offer. Some organizations also assess charting habits or case-based reasoning. Reviewing several local openings can help you compare timelines and expectations.
  • Do nurse practitioner jobs in Portland, Maine usually require experience in primary care, urgent care, or a specific specialty?

    Many openings in Portland, Maine welcome a mix of backgrounds, but prior experience in the matching setting is often preferred. Primary care jobs may favor chronic disease management and preventive care experience, while urgent care roles often look for fast-paced triage, acute assessment, and procedural comfort. Specialty clinics may want exposure to cardiology, orthopedics, behavioral health, or another defined area. Some employers will train strong recent graduates, especially if they hold the right certification and a solid clinical rotation record. Comparing similar postings can show how strict each employer is about prior practice.
  • What career growth opportunities are available for a nurse practitioner in the healthcare industry?

    This field offers several paths beyond a standard clinical caseload. In Maine, a nurse practitioner can move into lead provider roles, specialty practice, population health, telehealth, education, quality improvement, or administration. Some professionals advance into regional management, research, or academic teaching, while others deepen expertise in a focused area such as oncology, cardiology, or geriatrics. Additional certifications and continuing education can support higher responsibility and broader pay bands. Exploring current healthcare listings in Portland can help you see which employers support advancement, mentorship, and specialty development.

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117 jobs found

  • MaineHealth

    MaineHealth

    Today

    Physician associate/associate or acute care nurse practitioner trauma surgery

    MaineHealth Maine Medical Center Portland, ME is currently recruiting for a Physician Assistant (PA) or Acute Care Nurse Practitioner (ACNP) to join our Trauma Surgery team. Maine Medical Center...

    onsite, Portland, ME, United States
    Full TimeEntry with Degree
  • MaineHealth

    MaineHealth

    2 days ago

    Clinical nurse (rn) - neurosurgical/trauma/medical surgical unit (r6)

    Maine Medical Center Nursing Req #: 98226 This is a bargaining unit position Job Posting Date: 10/27/2026 This is a Clinical Nurse II vacancy open to RNs with at least one year of RN work experience....

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    3 days ago

    Clinical nurse (rn) - certified wound ostomy continence nurse

    Clinical Nurse (RN) - Certified Wound Ostomy Continence Nurse Maine Medical Center Nursing Req #: 62267 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work...

    onsite, Portland, ME, United States
    $93k – $138k/yrFull TimeMiddle (2-4 years)
  • 77 consultants

    77 consultants

    3 days ago

    Locum np (nurse practitioner), pa (physician's assistant) gastroenterology

    Description This is a contract, on-site position offering an opportunity to provide high-quality gastroenterology care within a collaborative clinical team. In this role, you will evaluate, diagnose,...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • N

    Northern Light Health

    6 days ago

    Hospital medicine app (nurse practitioner or physician associate)

    Northern Light Mercy Hospital is seeking a per diem Hospital Medicine APP (nurse practitioner or physician associate) to join its established inpatient medicine team in Portland, Maine. This is an...

    onsite, Portland, ME, United States
    $151k/yrPart TimeJunior (<2 years)
  • Bayside Comprehensive Treatment Center

    Bayside Comprehensive Treatment Center

    7 days ago

    Lpn dispensing nurse - prn

    Overview Outpatient MAT Opioid Treatment Program (OTP) Seeking: LPN Dispensing Nurse Per Diem Hours: Working on an as-needed basis. Monday - Friday, 4:30 AM - 12:00 PM Saturday, 5:30 AM - 12:00 PM...

    onsite, Portland, ME, United States
    $48k – $60k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - medical surgical unit (p4c) - new graduates welcome

    Maine Medical Center Nursing Req #: 87096 This is a bargaining unit position. Job Posting Date: 9/2/2026 This is a Clinical Nurse I vacancy open to candidates with 0-1 year of RN work experience....

    onsite, Portland, ME, United States
    $77k/yrPart TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner surgical float

    MaineHealth Maine Medical Center Portland, ME is currently recruiting for a full time Surgical Float (days/nights), Physician Associate (PA) or Acute Care Nurse Practitioner (ACNP), to join our care...

    onsite, Portland, ME, United States
    $131k – $169k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - general surgical unit (p3cd) - new graduates welcome

    Maine Medical Center Nursing Req #: 94362 This is a bargaining unit position. Job Posting Date: 9/21/2026 2 Positions available This is a Clinical Nurse I vacancy open to candidates with 0 – 1 year...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • N

    Northern Light Health

    8 days ago

    Pain management app (nurse practitioner or physician associate)

    Northern Light Mercy Hospital is seeking a full-time Advanced Practice Provider (Nurse Practitioner or Physician Associate) to join its established, successful Pain Management practice in Portland,...

    onsite, Portland, ME, United States
    $130k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner - orthopedics - foot & ankle

    Advanced Practice Provider Physician Assistant or Acute Care Nurse Practitioner MaineHealth Orthopedic Foot & Ankle Portland, ME Req # 93547 MaineHealth Orthopedics is looking to hire a PA or Acute...

    onsite, Portland, ME, United States
    $124k – $161k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - operating room - gyn/gu

    Maine Medical Center Nursing Req #: 97147 This is a Bargaining Unit Position Job Posting Date: 10/12/2026 Full Time/Days (This position will support GYN/GU) This is a Clinical Nurse 2 vacancy open to...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse educator (rn) - $20k sign-on bonus

    MaineHealth Corporate Professional - Clinical Req #: 86864 Full Time/Days This position requires schedule flexibility and could require day, evening and weekend commitments based on school/unit...

    onsite, Portland, ME, United States
    $97k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/associate or acute care nurse practitioner vascular surgery

    MaineHealth Maine Medical Center Portland, ME is currently recruiting for a Physician Assistant (PA) or Acute Care Nurse Practitioner (ACNP) to join our Vascular Surgery team. Maine Medical Center...

    onsite, Portland, ME, United States
    Full TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse ii - mmcp (u)

    Clinical Nurse II - MMCP (U) Maine Medical Center Nursing Req #: 1401 Summary: The Clinical Nurse supports Maine Medical Center's mission, vision, and values by exhibiting the following behaviors:...

    onsite, Portland, ME, United States
    Full TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Fellowship -physician associate/acute care nurse practitioner surgical critical care

    MaineHealth Maine Medical Center Advanced Practice Provider – Critical Care Fellowship The program has biannual cohorts starting in April and October. Application Deadlines are September 15th for the...

    onsite, Portland, ME, United States
    $79k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner critical care per diem

    MaineHealth Maine Medical Center Portland, ME, is recruiting for a Physician Associate/Physician Assistant (PA) or Acute Care Nurse Practitioner (ACNP) to join our Critical Care team. This is a Per...

    onsite, Portland, ME, United States
    $161k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn)- cardiology/cardiac surgery (r1)

    Clinical Nurse (RN) - Cardiology/Cardiac Surgery Maine Medical Center Nursing Req #: 94706 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This...

    onsite, Portland, ME, United States
    $83k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Acute care nurse practitioner/physician associate palliative care mmc portland, me

    MaineHealth Maine Medical Center Portland, ME, is seeking an experienced Part-Time (0.75 FTE/30 hrs) Advance Practice Provider (Acute Care Nurse Practitioner or Physician Associate) to join our...

    onsite, Portland, ME, United States
    $89k – $116k/yrPart TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse practitioner or physician associate - geriatric medicine portland, me

    MaineHealth Geriatric Medicine is seeking a Physician Associate (PA) or Nurse Practitioner (NP) to care for patients in partnered facilities including long term care, assisted living and skilled...

    onsite, Portland, ME, United States
    $119k – $154k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - operating room - orthopedics

    Maine Medical Center Nursing Req #: 96717 This is a Bargaining Unit Position Job Posting Date: 10/12/2026 2 Positions Available Full Time/Days (40 hours per week) This position will support the...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - neurosurgical/trauma/medical surgical unit (r6) - new graduates welcome

    Maine Medical Center Nursing Req #: 91649 This is a Bargaining Unit Position Job Posting Date: 9/2/2026 4 Positions available R6 is a dynamic 24-bed neurosurgical / trauma unit with an embedded 9-bed...

    onsite, Portland, ME, United States
    $77k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Acute care nurse practitioner/physician associate palliative care mmc portland

    MaineHealth Maine Medical Center Portland, ME, is seeking an experienced full-time (1.00 FTE/40 hrs) Advance Practice Provider (Acute Care Nurse Practitioner or Physician Associate) to join our...

    onsite, Portland, ME, United States
    $119k – $154k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse i - mmcp (u)

    Maine Medical Center Nursing Req #: 598 Summary : The Clinical Nurse supports Maine Medical Center's mission, vision, and values by exhibiting the following behaviors: excellence, competence,...

    onsite, Portland, ME, United States
    Full TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate or assistant/acute care nurse practitioner cardiovascular surgery icu nocturnist

    MaineHealth Maine Medical Center, Portland, ME, is recruiting for a Physician Associate (PA) or Acute Care Nurse Practitioner (ACNP) Nocturnist with 3-5 years of critical care experience to work at...

    onsite, Portland, ME, United States
    $180k – $233k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner hospital medicine biddeford/portland, me

    MaineHealth Maine Medical Center is seeking a full-time Physician Associate /Assistant (PA) or Acute Care Nurse Practitioner (ACNP) to care for patients in the hospital at MaineHealth in Biddeford...

    onsite, Biddeford, ME, United States
    Full TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate or acute care nurse practitioner - inpatient endocrinology & diabetes

    Advanced Practice Provider – Inpatient MaineHealth Endocrinology and Diabetes Location: Scarborough, ME Schedule: Full-time - Day Shift Req#: 93525 MaineHealth Endocrinology and Diabetes is seeking...

    onsite, Portland, ME, United States
    $116k – $150k/yrFull TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner cardiology inpatient per-diem, portland, me

    Job Description MaineHealth Maine Medical Center Portland, ME is recruiting for an experienced Physician Associate (PA) or Acute Care Nurse Practitioner (ACNP) to work in the Cardiology Advanced...

    onsite, Portland, ME, United States
    $161k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse practitioner/physician associate thoracic surgery oncology part-time portland, me

    MaineHealth Maine Medical Center Thoracic Surgery Oncology is a growing division seeking a part-time (0.40 FTE/16 hrs) outpatient Nurse Practitioner or Physician Associate to support our Thoracic...

    onsite, Portland, ME, United States
    $47k – $61k/yrPart TimeJunior (<2 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate/acute care nurse practitioner - bariatric and minimally invasive surgery

    The MaineHealth Maine Medical Center Department of Surgery is seeking a collaborative and motivated Advanced Practice Provider (APP) to join our Bariatric and Minimally Invasive Surgery team. This...

    onsite, Portland, ME, United States
    $131k – $169k/yrFull TimeEntry with Degree
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse manager (rn) - neonatal intensive care unit (nicu)

    Nurse Manager (RN) - Neonatal Intensive Care Unit (NICU) Barbara Bush Children’s Hospital Management/Leadership Req #: 83442 Full Time Evenings Maine Medical Center is the state’s largest medical...

    onsite, Portland, ME, United States
    $132k – $179k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Nurse manager (rn) - inpatient medical psychiatry (p6)

    Maine Medical Center Management/Leadership Req #: 93621 Seeking a leader to oversee a 21-bed Inpatient Medical Psychiatry unit caring for a medically complex patient population, with a strong focus...

    onsite, Portland, ME, United States
    $132k – $179k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Physician associate or assistant/acute care nurse practitioner cardiovascular surgery floor/imc unit

    MaineHealth Maine Medical Center, Portland, ME, is recruiting for a Physician Assistant (PA) or Acute Care Nurse Practitioner (ACNP) with 3-5 years of cardiovascular experience to work at Maine...

    onsite, Portland, ME, United States
    $135k – $174k/yrFull TimeMiddle (2-4 years)
  • MaineHealth

    MaineHealth

    8 days ago

    Clinical nurse (rn) - inpatient psychiatry (p6)

    Maine Medical Center Nursing Req #: 90187 This is a Clinical Nurse II vacancy open to candidates with greater than 1 year of RN work experience. This is a bargaining unit position. Date posted:...

    onsite, Portland, ME, United States
    $83k/yrFull TimeJunior (<2 years)
  • Maine Medical Center

    Maine Medical Center

    13 days ago

    Physician associate/acute care nurse practitioner cardiac icu portland, me

    Job Description Cardiac Intensive Care Unit (CICU) Advanced Practice Provider Maine Medical Center – Portland, Maine Cardiovascular Service Line Position Summary Maine Medical Center (MMC) in...

    onsite, Portland, ME, United States
    $139k – $179k/yrFull TimeJunior (<2 years)
  • Martin’s Point Health Care

    Martin’s Point Health Care

    14 days ago

    Nurse practitioner - access clinic

    Join Martin's Point Health Care - an innovative, not-for-profit health care organization offering care and coverage to the people of Maine and beyond. As a joined force of "people caring for people,"...

    onsite, Portland, ME, United States
    $135k – $160k/yrPart TimeJunior (<2 years)
  • The Vascular Care Group

    The Vascular Care Group

    15 days ago

    Procedural nurse (portland) (per diem)

    Overview This role is responsible for providing nursing services in a vascular Office-Based Lab setting. The Cath Lab (otherwise known as Office-Based Lab) Nurse will collaborate with clinical...

    onsite, Portland, ME, United States
    $81k/yrPart TimeJunior (<2 years)
  • CFG HEALTH SYSTEM LLC

    CFG HEALTH SYSTEM LLC

    25 days ago

    Registered nurse

    Job Details: Job Location: Cumberland County Jail - ME - Portland, ME Position Type: Full Time Salary Range: Undisclosed Job Shift: Night JOB SUMMARY Utilizes the nursing process to meet a variety of...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • Portland Center Assisted Living

    Portland Center Assisted Living

    a month ago

    Nurse manager -lpn

    PCAL is part of our First Atlantic Healthcare family of nursing and assisted living facilities, 100% Maine based and family-owned. We take pride in service to others, knowing we make a difference in...

    onsite, Portland, ME, United States
    Full TimeJunior (<2 years)
  • Cherokee Federal

    Cherokee Federal

    a month ago

    Part-time nurse practitioner, aprn, fnp

    A government contract requires that this position be restricted to U.S. citizens. This position requires a Common Access Card (CAC), and the ability to pass the U.S. Department of Defense (DoD)...

    onsite, Albany, NY, United States
    $117k – $125k/yrPart TimeJunior (<2 years)

10,000,000+ more jobs available!