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  4. Nurse Practitioner

Onsite Nurse Practitioner jobs in Chicago, Illinois, USA

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Nurse Practitioner Jobs in Chicago — On-Site Opportunities Await

Chicago's healthcare network continues to expand, creating strong demand for nurse practitioner jobs in Chicago across hospitals, clinics, and specialty practices. This on-site role offers 500+ open positions for professionals ready to deliver exceptional patient care in a dynamic urban setting. With Illinois's growing healthcare sector, now is an ideal time to explore nurse practitioner vacancies in one of the Midwest's largest medical hubs.

Successful candidates bring strong clinical assessment skills, sound diagnostic judgment, and the ability to manage diverse patient populations with compassion and precision. Employers seeking to hire a nurse practitioner typically look for certification, strong communication abilities, and comfort working collaboratively within multidisciplinary teams. Adaptability, attention to detail, and a commitment to evidence-based practice remain essential, especially in fast-paced clinical environments where patient needs can shift quickly throughout the day.

On-site work remains the standard for nurse practitioner positions in Chicago, given the hands-on nature of patient care and the need for direct collaboration with physicians and support staff. Local hospitals and outpatient centers report steady hiring activity, driven by population growth and increasing healthcare access across Illinois. This sustained demand makes Chicago a promising market for clinicians seeking long-term career stability and professional growth.

If you're ready to take the next step in your healthcare career, explore current openings through Global Work AI and connect with employers actively hiring nurse practitioners. Discover how your skills can make a meaningful difference in Chicago's thriving medical community today.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average nurse practitioner salary in Chicago?

    In Chicago, pay for a nurse practitioner typically falls in the low six-figure range, with many roles landing around $115,000 to $140,000 a year depending on specialty, employer, and years of experience. Hospital systems, outpatient groups, and urgent care centers may offer different base rates, shift differentials, and bonuses. Compensation also tends to vary with board certification and advanced practice focus areas such as family medicine, acute care, or psychiatry. Reviewing current Chicago listings and comparing total rewards can help set realistic expectations.
  • What qualifications, certifications, and Illinois licensure are required for a nurse practitioner job?

    Most employers in Illinois expect an active RN license, an MSN or DNP from an accredited program, national board certification in the relevant population focus, and full Illinois APRN authority. Prescriptive authority may also be needed, along with a valid DEA registration if controlled substances are part of the role. Many Chicago healthcare settings prefer prior clinical experience and strong documentation habits. Because hospital and clinic requirements can differ, it helps to verify whether the posting asks for family, adult-gerontology, pediatric, or psych certification before applying.
  • What clinical skills are most important for an on-site nurse practitioner role?

    Strong assessment ability is essential, especially when patients present with mixed or urgent symptoms in a busy Chicago setting. Employers also value sound diagnostic reasoning, medication management, procedure competence, and comfort with EHR documentation. Communication matters just as much, since an on-site nurse practitioner works closely with physicians, nurses, and support staff in real time. Skills in patient education, triage, and evidence-based care are especially important in hospitals, clinics, and specialty practices. Reviewing the unit or department focus can help you match your strengths to the opening.
  • What are the main responsibilities of a nurse practitioner in a Chicago healthcare setting?

    Day to day, the role usually includes evaluating patients, ordering and interpreting tests, developing treatment plans, prescribing when allowed, and monitoring outcomes over time. In Chicago healthcare systems, a nurse practitioner may also coordinate referrals, manage chronic conditions, support preventive care, and document visits in the electronic record. The exact scope depends on the setting, whether that is primary care, specialty care, urgent care, or inpatient medicine. Many employers also expect collaboration with physicians and interdisciplinary teams, so it helps to read the posting closely for scope details.
  • What does the hiring process usually look like for nurse practitioner jobs?

    The process often starts with an online application and resume review, followed by recruiter screening, hiring manager interviews, and sometimes a panel or clinical interview. Chicago employers may ask about certification status, patient volume experience, charting systems, and comfort with the department’s pace. References, license verification, background checks, and credentialing commonly come next, especially in hospital-based settings. Some organizations also request case-based questions or skills discussion before making an offer. Checking timelines in each posting can help you prepare for the next step without delay.
  • What work schedule, shift expectations, and on-site conditions should I expect for a nurse practitioner role in Chicago?

    Schedules vary widely, but many on-site nurse practitioner jobs in Chicago involve weekday daytime hours, while hospital and urgent care roles may include evenings, weekends, holidays, or rotating coverage. Some positions are full time with call expectations, especially in inpatient or specialty services. On-site conditions can include fast-paced patient flow, shared workspace, and regular coordination with nursing and medical teams. Weather, commuting, and parking can also affect the experience in Chicago, so it is useful to compare shift patterns, call burdens, and location details before choosing a role.
  • What career growth opportunities are available for nurse practitioners in Illinois healthcare systems?

    Illinois healthcare systems often offer clear paths into specialty practice, lead clinician roles, service-line supervision, quality improvement, and education. A nurse practitioner in Chicago may also move into advanced practice leadership, research support, population health, or telehealth-adjacent coordination roles, depending on the employer. Additional certifications and a DNP can strengthen options for promotion and higher responsibility. Larger hospital networks may provide mentorship, committee work, and internal mobility across departments. Exploring related openings can help you identify which system offers the best long-term fit for your goals.

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500+ jobs found

  • UChicago Medicine

    UChicago Medicine

    Today

    Clinical nurse specialist, full-time days

    Join UChicago Medicine, as a Clinical Nurse Specialist (CNS) in our Nursing Administration department. The Clinical Nurse Specialist (CNS) is a Master's or Doctorate prepared Advanced Practice Nurse...

    onsite, Chicago, IL, United States
    Full TimeLead / Manager
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    a day ago

    Physician assistant or nurse practitioner - emergency medicine casual rotating

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $127k – $166k/yrPart TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    a day ago

    Physician assistant or nurse practitioner - emergency medicine, full-time, nights

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $127k – $166k/yrFull TimeJunior (<2 years)
  • One Medical

    One Medical

    a day ago

    Per diem family medicine physician assistant or nurse practitioner (casual employee) - chicago proper

    About Us One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn’t your average doctor’s office....

    onsite, Chicago, IL, United States
    $135k/yrPart TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    a day ago

    Physician assistant or acute care nurse practitioner - surgical intensive care unit (sicu), full-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $127k – $166k/yrFull TimeJunior (<2 years)
  • Advocate Health

    Advocate Health

    a day ago

    Nurse practitioner or physician assistant - palliative care - immc

    Department: 02310 AMG Illinois Masonic - Palliative Care Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: Full-time, 40 hours/week 8-hour onsite...

    onsite, Chicago, IL, United States
    $111k/yrFull TimeJunior (<2 years)
  • Prime Healthcare Illinois Medical Group

    Prime Healthcare Illinois Medical Group

    2 days ago

    Orthopedic surgery nurse practitioner (np)

    Overview Orthopedic Surgery NP for St Mary's of Nazareth- Chicago Location: St. Mary's of Nazareth- Chicago Job Type: Full-Time Prime Healthcare is seeking a dedicated and compassionate Nurse...

    onsite, Chicago, IL, United States
    $110k/yrFull TimeJunior (<2 years)
  • Shriners Children's

    Shriners Children's

    2 days ago

    Advanced practice provider - nurse practitioner or physician assistant

    Company Overview Shriners Children’s is an organization that respects, supports, and values each other. Named as the 2025 best mid-sized employer by Forbes, we are engaged in providing excellence in...

    onsite, Chicago, IL, United States
    $106k/yrPart TimeJunior (<2 years)
  • WellNow Urgent Care

    WellNow Urgent Care

    3 days ago

    Physician assistant (pa) or nurse practitioner (np)

    WellNow Urgent Care is one of the fastest-growing providers of urgent medical care in the United States, with more than 150 clinics across Illinois, Indiana, Michigan, New York, and Pennsylvania....

    onsite, Chicago, IL, United States
    $161k/yrFull TimeJunior (<2 years)
  • Sinai Chicago

    Sinai Chicago

    5 days ago

    Nurse practitioner

    About Us At Sinai Health System d/b/a Sinai Chicago, we take health care personally. Excellence in health care is about more than just medicine, technology, tests, and treatments, it is about really...

    onsite, Chicago, IL, United States
    Part TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    5 days ago

    Acute care nurse practitioner or physician assistant - general cardiology and advanced heart failure, full-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $123k – $161k/yrFull TimeJunior (<2 years)
  • VITAS Healthcare

    VITAS Healthcare

    5 days ago

    Nurse practitioner

    VITAS® Healthcare is the nation’s leading provider of end-of-life care, and has the resources and expertise to support your personal and professional growth. As a member of the VITAS team, you’ll...

    onsite, Chicago, IL, United States
    Full TimeEntry with Degree
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    5 days ago

    Physician assistant or acute care nurse practitioner - cardiac surgery, part-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $133k – $174k/yrPart TimeJunior (<2 years)
  • Genesis Orthopedics & Sports Medicine

    Genesis Orthopedics & Sports Medicine

    6 days ago

    Orthopedic physician assistant/nurse practitioner

    Most APP roles in orthopedics look the same: follow a surgeon around, fill out notes, operate inside a box someone else drew. You're credentialed, experienced, and capable of more — and the system...

    onsite, Chicago, IL, United States
    Full TimeMiddle (2-4 years)
  • Advocate Health

    Advocate Health

    7 days ago

    Clinical nurse specialist (aprn)

    Department: 34207 Advocate Illinois Masonic Medical Center - Nursing Staff Development Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: 40hrs...

    onsite, Chicago, IL, United States
    $103k/yrFull TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    8 days ago

    Nurse clinician - physician primary care full-time days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $70k/yrFull TimeJunior (<2 years)
  • Medlead Careers

    Medlead Careers

    10 days ago

    Nurse practitioner or physician assistant

    Apply today and take the opportunity to support the geriatric population while making a meaningful difference in their lives! A fast-growing long-term care organization is seeking a dedicated and...

    onsite, Chicago, IL, United States
    $115k – $145k/yrFull TimeJunior (<2 years)
  • Cyitechsearch

    Cyitechsearch

    12 days ago

    Family nurse practitioner

    Job Details Focus on patients and help them achieve better health in onsite corporate clinics. Go above and beyond in patient care by helping patients become empowered to take control of their...

    onsite, Chicago, IL, United States
    $40k – $60k/yrFull TimeJunior (<2 years)
  • Lawndale Christian Health Center

    Lawndale Christian Health Center

    12 days ago

    Nurse practitioner

    Position Summary The Nurse Practitioner provides professional comprehensive primary medical care to ambulatory LCHC patients in collaboration with health center staff physicians. As a member of a...

    onsite, Chicago, IL, United States
    $89k/yrFull TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    12 days ago

    Physician assistant or acute care nurse practitioner - endocrinology full time days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $123k – $161k/yrFull TimeJunior (<2 years)
  • Advocate Health

    Advocate Health

    12 days ago

    Aprn, advanced practice nurse, outpatient cardiology, chicago - full time

    Department: 02050 AMG Chicago Imani Village - Cardiology Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: Schedule: Monday–Friday, 8:00 AM – 4:30...

    onsite, Chicago, IL, United States
    $111k/yrFull TimeJunior (<2 years)
  • Prime Healthcare Illinois Medical Group

    Prime Healthcare Illinois Medical Group

    13 days ago

    Nurse practitioner – rheumatology

    Overview Job Title: Nurse Practitioner - Rheumatology Location: Chicago, Illinois and Evanston, Illinois Organization: Prime Healthcare Illinois Medical Group Hospitals: St. Mary of Nazareth Hospital...

    onsite, Chicago, IL, United States
    $120k – $130k/yrFull TimeJunior (<2 years)
  • Prime Healthcare Illinois Medical Group

    Prime Healthcare Illinois Medical Group

    13 days ago

    Primary care -nurse practitioner-st mary of nazareth-chicago

    Overview Primary Care Nurse Practitioner Location: Prime Healthcare Illinois Medical Center - St. Mary of Nazareth - Chicago, IL Job Type: Full-Time Prime Healthcare Illinois Medical Center is...

    onsite, Chicago, IL, United States
    $110k/yrFull TimeJunior (<2 years)
  • UChicago Medicine

    UChicago Medicine

    15 days ago

    Advanced practice provider - physician assistant/nurse practitioner, center for transformative care (ctc)- pt- days

    Join&nbsp;the&nbsp;University of Chicago Medicine&nbsp;as an Advanced Practice Provider (Nurse Practitioner or Physician Assistant)&nbsp;- Care Transitions Clinic.&nbsp; Up to $10,000.00 Sign on...

    onsite, Chicago, IL, United States
    Part TimeJunior (<2 years)
  • AdventHealth

    AdventHealth

    16 days ago

    Family medicine nurse practitioner

    Overview UChicago Medicine AdventHealth Bolingbrook, GlenOaks, Hinsdale and La Grange hospitals are affiliated with UChicago Medicine, one of the top academic medical centers in the country. We are...

    onsite, Bolingbrook, IL, United States
    $115k – $125k/yrFull TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    19 days ago

    Physician assistant or acute care nurse practitioner - cardiac surgery, full-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $133k – $174k/yrFull TimeJunior (<2 years)
  • One Medical

    One Medical

    20 days ago

    Nurse practitioner or physician assistant (fulton market clinic)

    About Us One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn’t your average doctor’s office....

    onsite, Chicago, IL, United States
    $127k – $152k/yrFull TimeJunior (<2 years)
  • Nextera HealthCare

    Nextera HealthCare

    20 days ago

    Licensed practical nurse

    KerixHealth is a rapidly growing, innovative healthcare company that provides higher quality primary care to patients to improve outcomes, manage medical costs, and deliver an unmatched experience...

    onsite, Chicago, IL, United States
    Full TimeMiddle (2-4 years)
  • Duly Health and Care

    Duly Health and Care

    21 days ago

    Nurse practitioner, geriatrics

    If you are a current Duly/SBC/QMG employee, please apply through the Internal Career Site. At Duly Health and Care, you are empowered to deliver care that reflects the full scope of your training -...

    onsite, Chicago, IL, United States
    $100k/yrFull TimeEntry with Degree
  • The IMA Group

    The IMA Group

    21 days ago

    Nurse practitioner – va evaluations (3 days/week) in chicago, il

    Nurse Practitioner – VA Disability Medical Evaluations (3 Days/Week) Schedule: 3 weekday shifts per week | 8-hour days | No treatment or prescribing Salary: $115,000–$125,000 annually (pro-rated...

    onsite, Chicago, IL, United States
    $115k – $125k/yrPart TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    22 days ago

    Physician assistant or acute care nurse practitioner - cardiac recovery and observation and invasive cardiac post anesthesia care , full-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $123k – $161k/yrFull TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    22 days ago

    Nurse practitioner or physician assistant – epilepsy program, full-time, days

    Company Description Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $123k – $161k/yrFull TimeJunior (<2 years)
  • Northwestern Memorial Healthcare

    Northwestern Memorial Healthcare

    22 days ago

    Nurse practitioner or physician assistant – pre op clinic, full-time, days

    Company Description At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the...

    onsite, Chicago, IL, United States
    $123k – $161k/yrFull TimeJunior (<2 years)
  • Concentra

    Concentra

    22 days ago

    Nurse practitioner or physician assistant clinical manager

    Overview Monthly and Quarterly Bonus Incentives! Are you ready to take your career to new heights? At Concentra, you will be a vital member of our patient care team and play a crucial role in...

    onsite, Chicago, IL, United States
    $125k – $160k/yrFull TimeJunior (<2 years)
  • Vohra Physicians

    Vohra Physicians

    23 days ago

    Nurse practitioner (np) - chicago, il

    Nurse Practitioner (NP) Position with National Wound Physician Group Get Your Life Back – No Nights, No Call, No Weekends Join Vohra Wound Physicians, the largest and most trusted wound care group in...

    onsite, Chicago, IL, United States
    Full TimeJunior (<2 years)
  • AccentCare, Inc.

    AccentCare, Inc.

    23 days ago

    Nurse practitioner, palliative care prn

    Overview Nurse Practitioner / NP, Palliative Care Position: Nurse Practitioner Palliative Care Job ID: 76303 Remote/Virtual Position: No Coverage Area: Downtown Chicago SNIF Facility Find Your...

    onsite, Chicago, IL, United States
    $101k/yrPart TimeJunior (<2 years)
  • ACCESS Community Health Network

    ACCESS Community Health Network

    a month ago

    Women's health advanced practice registered nurse (aprn) - access brandon/dpv

    We are an equal opportunity employer. All qualified applicants will receive consideration for employment. We do not discriminate for any reason. We welcome talented individuals who believe in our...

    onsite, Chicago, IL, United States
    Full TimeJunior (<2 years)
  • AUNT MARTHAS HEALTH AND WELLNESS INC

    AUNT MARTHAS HEALTH AND WELLNESS INC

    a month ago

    Family nurse practitioner- or physician assistant

    Family Nurse Practitioner (FNP) or Physicians Assistant - Southeast Side Clinic 3528 E 118th, St Chicago, IL 60617 Salary $110,000 - $130,000 Aunt Martha’s Health and Wellness boldly commits to...

    onsite, Chicago, IL, United States
    $110k/yrFull TimeJunior (<2 years)
  • The IMA Group

    The IMA Group

    a month ago

    Psychiatric nurse practitioner or physician assistant – clinical research - chicago

    Psychiatric Nurse Practitioner (PMHNP) or Physician Assistant – Clinical Research Chicago, IL | Full-Time | Monday–Friday Bring your psychiatric expertise to clinical research. Join IMA Clinical...

    onsite, Chicago, IL, United States
    $130k – $150k/yrFull TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    a month ago

    Infection control practitioner - registered nurse, rn

    Kindred Hospital Chicago - North is a 164-bed long-term acute care hospital offering the same in depth care you would receive in a traditional hospital, but for an extended recovery period. We...

    onsite, Chicago, IL, United States
    $74k – $109k/yrFull TimeJunior (<2 years)

10,000,000+ more jobs available!