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  3. Charleston
  4. Travel Nurse

Onsite Travel Nurse jobs in Charleston, South Carolina, USA

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Travel Nurse Jobs in Charleston — On-Site Opportunities Await

Hospitals and clinics across Charleston are actively hiring for travel nurse jobs in Charleston, reflecting the region's growing need for flexible, skilled nursing talent. This on-site position offers 174 open roles for professionals ready to bring their expertise to diverse healthcare settings. South Carolina's healthcare systems continue to expand, creating opportunities for nurses who thrive in new environments.

Successful candidates typically bring strong clinical judgment, adaptability, and excellent communication skills to each assignment. Travel nurse vacancies demand the ability to quickly learn new procedures, electronic health record systems, and hospital protocols while maintaining compassionate patient care. Certifications such as ACLS or BLS are often required, along with a valid nursing license and a solid record of working efficiently under pressure. Employers value nurses who can mentor junior staff and collaborate with multidisciplinary teams.

On-site work remains the standard for travel nurse positions, since direct patient interaction and hands-on care cannot be replicated remotely. In Charleston, healthcare facilities are expanding staffing programs to meet seasonal surges and specialty care needs, making this an excellent time to hire a travel nurse with proven adaptability. The local market rewards professionals willing to relocate temporarily, offering competitive pay and housing support.

If you're ready to take the next step in your nursing career, explore current travel nurse opportunities through Global Work AI and discover roles that match your skills and goals. Charleston's healthcare community is waiting for dedicated professionals to join its ranks, and Global Work AI connects you to the facilities that need you most.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average travel nurse salary in Charleston?

    In Charleston, South Carolina, travel nurse pay is often higher than staff pay because facilities are filling urgent short-term needs. Most travel nurse roles in the USA are quoted by weekly taxable pay plus stipends, and Charleston rates commonly reflect specialty, shift, and seasonal demand. A registered nurse on assignment may see total packages that vary widely, but many offers land in a competitive range compared with other coastal markets. For the clearest picture, review current listings side by side and compare hourly base pay, stipends, and overtime rules.
  • What qualifications do I need to become a travel nurse?

    A solid nursing background is the starting point, along with recent bedside experience in an acute care setting. Most travel nurse employers in Charleston and across the USA look for an active RN license, at least one to two years of current clinical experience, and confidence working independently on a new unit. Strong charting skills, adaptability, and fast teamwork matter too. Many recruiters also favor candidates with specialty exposure, such as med-surg, ICU, or telemetry. If you are early in your career, it helps to compare common requirements across similar on-site roles.
  • What nursing licenses and certifications are required for a travel nurse job in South Carolina?

    For an on-site travel nurse role in South Carolina, you generally need an active, unrestricted RN license recognized by the state board. Many nurses work in Charleston through compact licensure if they hold a multistate Nurse Licensure Compact credential in a compact state. Some assignments may also ask for BLS, and specialty units often require ACLS, PALS, NIHSS, or similar credentials depending on patient population. Hospitals may request recent vaccinations, background checks, and fit testing as well. Reviewing current facility requirements can help you prepare before applying.
  • What are the typical on-site responsibilities of a travel nurse in Charleston?

    Day-to-day duties usually mirror those of permanent bedside staff, with added emphasis on quick orientation and flexibility. In Charleston, a travel nurse may assess patients, administer medications, update care plans, document in the electronic health record, and coordinate with physicians, therapists, and support teams. Depending on the unit, responsibilities can include wound care, monitoring vital signs, discharge education, and responding to changes in condition. Because assignments are on-site, you also need to adapt quickly to local workflows and equipment. Checking unit descriptions closely can reveal how duties differ by specialty.
  • How long are most travel nurse assignments in Charleston?

    Most travel nurse contracts in Charleston run about 13 weeks, which is the industry standard across the USA. That said, some hospital needs are shorter, while extensions are common when staffing gaps continue or the nurse and unit are a good fit. Emergency demand, census changes, and specialty coverage can all affect timing. Many professionals use one assignment as a bridge to the next, so it helps to track renewal options early. When comparing postings, look at contract length, start date, and extension terms together rather than in isolation.
  • What specialties are most in demand for travel nurse jobs in Charleston?

    High-need areas in Charleston often include medical-surgical, ICU, telemetry, emergency, labor and delivery, and perioperative nursing. Like many South Carolina markets, the city also sees steady demand for step-down, oncology, and sometimes pediatric or neonatal coverage, depending on the facility. Coastal hospitals and surgical centers may prioritize nurses who can float, handle higher patient acuity, and work nights or weekends. Specialty demand can shift with census and season, so the best approach is to compare current openings by unit, shift, and experience level before choosing a path.
  • What benefits and housing support are usually offered with travel nurse jobs?

    Travel nurse packages commonly include weekly pay, stipends for housing and meals, health coverage options, licensure help, and sometimes completion bonuses or referral incentives. In Charleston, housing support may come as a tax-free stipend, employer-arranged furnished housing, or guidance finding short-term rentals near the facility. Some contracts also offer travel reimbursement, 401(k) access, and paid time off depending on the agency. Because housing costs can vary around the city, it is wise to compare the full compensation picture, not just the base rate, when reviewing listings.

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174 jobs found

  • NHC Careers

    NHC Careers

    a day ago

    Night shift nursing supervisor, rn registered nurse

    Position: Night Shift Supervisor, Registered Nurse (RN) Are you looking to make a difference in the lives of others by sharing your care and compassion? Do you enjoy connecting with your patients...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    2 days ago

    Registered nurse i - art 4e cardiothoracic stepdown unit

    Job Description Summary Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    3 days ago

    Registered nurse ii - pediatric empath - mental health

    Job Description Summary EmPATH stands for “Emergency Psychiatry Assessment, Treatment and Healing." EmPATH Units deliver acute interventions for behavioral healthcare patients by moving them out of...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Anders Group

    Anders Group

    4 days ago

    Travel registered nurse cath lab tech - $2263/week

    Anders Group is hiring a Travel Cath Lab Tech Registered Nurse (RN) in CHARLESTON, SC Location: CHARLESTON, SC Start Date: 10/23/2026 Contract Length: 13 Weeks Shift: 3x12 Nights Practice Area:...

    onsite, Charleston, SC, United States
    $109k/yrFull TimeJunior (<2 years)
  • Anders Group

    Anders Group

    4 days ago

    Travel registered nurse cath lab tech - $2516/week

    Anders Group is hiring a Travel Cath Lab Tech Registered Nurse (RN) in CHARLESTON, SC Location: CHARLESTON, SC Start Date: 11/16/2026 Contract Length: 13 Weeks Shift: 5x8 Days Practice Area: Hospital...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Hoar

    Hoar

    5 days ago

    Traveling assistant safety manager

    The Assistant Safety Manager is responsible for overseeing the administration of the company Health and Safety Program (HSP) and contractual safety requirements to prevent and correct unsafe working...

    onsite, Charleston, SC, United States
    Full TimeMiddle (2-4 years)
  • HCA Healthcare

    HCA Healthcare

    6 days ago

    Emergency room clinical nurse coordinator rn

    As the nation’s largest private employer of Registered Nurses, we’re honored by the trust of over 100,000 nurses and committed to supporting safe, high-quality care for which they can practice....

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • HCA Healthcare

    HCA Healthcare

    6 days ago

    Rn manager er

    Last year our HCA Healthcare colleagues invested over 156,000 hours volunteering in our communities. As a(an) RN Manager ER with HCA Healthcare Trident Hospital you can be a part of an organization...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    8 days ago

    Registered nurse (rn) weekend only – nephrology – roper hospital

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 36 Work Shift: Days (United States of America) Summary of Primary Function Delivers patient care utilizing...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • SC AQUARIUM

    SC AQUARIUM

    8 days ago

    Education interpreter, seasonal/pt

    Job Summary: This position is designed to be an ambassador for the Aquarium through a variety of on-site and off-site educational programs. Duties include participating in offsite outreaches, member...

    onsite, Charleston, SC, United States
    Part TimeJunior (<2 years)
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    8 days ago

    Registered nurse (rn) - medical intermediate care/hospitalist - roper hospital

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 36 Work Shift: Nights (United States of America) Shift Schedule: 3 night shifts a week 7:00pm-7:30am ,...

    onsite, Charleston, SC, United States
    Full TimeMiddle (2-4 years)
  • Crescent Hospice

    Crescent Hospice

    8 days ago

    Volunteer opportunity (hospice)

    Overview Are you looking to make a meaningful impact in your community? Join Crescent Hospice's dedicated volunteer team and bring joy, comfort, and support to those who need it most. We offer a...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • AdamsPlace

    AdamsPlace

    10 days ago

    Med tech / caregiver 7am-3pm weekends only

    WEEKENDS ONLY – Med Tech/Caregiver The Palmettos of Charleston is seeking a reliable and compassionate Med Tech/Caregiver to join our weekend team. You will provide resident care under the...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • DaVita Kidney Care

    DaVita Kidney Care

    13 days ago

    Registered nurse

    Posting Date 10/16/2026 1964 Ashley River Rd Ste D-3, Charleston, South Carolina, 29407-4782, United States of America Make a real impact—every day. As a DaVita RN, you’ll ensure compassionate and...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    15 days ago

    Registered nurse (rn) - nsg bone marrow transplant - roper hospital

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 36 Work Shift: Nights (United States of America) Summary of Primary Function Delivers patient care...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Monroe+Biomedical+Research

    Monroe+Biomedical+Research

    17 days ago

    Clinical research nurse practitioner / physician assistant

    ABOUT THE ROLE Monroe Biomedical Research (MBR) is growing, and we are seeking an experienced, patient-focused Clinical Research Nurse Practitioner/Physician Assistant to join our Charleston team....

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    20 days ago

    Registered nurse i (new graduate) - 10e orthopedics

    Job Description Summary MUSC’s Orthopedic Unit is located on 10 East in the Main Hospital in beautiful downtown Charleston. 10 East is a 20-bed acute care, post-operative unit, specializing in...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    20 days ago

    Registered nurse i (new graduate) - 6e stepdown transplant

    Job Description Summary Main 6E Transplant is a dynamic 22-bed adult inpatient unit dedicated to caring for fresh post-operative solid organ abdominal transplant patients. Our nurses play a vital...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    20 days ago

    Registered nurse i - (new graduate) - art 4e cardiothoracic stepdown unit

    Job Description Summary Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Prisma Health Urgent Care

    Prisma Health Urgent Care

    21 days ago

    Urgent care nurse practitioner or physician assistant- charleston, sc (float)

    Prisma Health Urgent Care seeks talented, patient-oriented Physician Assistants and Nurse Practitioners who are relentlessly dedicated to ensure the delivery of exceptional customer service by...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    22 days ago

    Registered nurse i (new graduate) - 9e neuroscience stepdown unit

    Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Select Specialty Hospital - Charleston

    Select Specialty Hospital - Charleston

    23 days ago

    Student nurse tech - per diem

    Overview Position: Student Nurse Tech (Future Registered Nurse) Location: Select Specialty Hospital - Charleston Schedule: Per Diem Compensation: $18.00 per hour Sign On Bonus: $1,500 This position...

    onsite, Charleston, SC, United States
    $36k/yrPart TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    23 days ago

    Nurse navigator - inpatient oncology transitions navigator

    Job Description Summary The Oncology Nurse Navigator is a professional registered nurse with oncology knowledge who provides individualized support to patients and caregivers to overcome healthcare...

    onsite, Charleston, SC, United States
    Full TimeMiddle (2-4 years)
  • Fresenius Medical Care

    Fresenius Medical Care

    23 days ago

    Outpatient registered nurse - rn

    PURPOSE AND SCOPE: The professional registered nurse Outpatient RN CAP 1 is an entry level designation into the Clinical Advancement Program (CAP). This position is accountable and responsible for...

    onsite, Charleston, SC, United States
    Full TimeLead / Manager
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    23 days ago

    Registered nurse (rn) - emergency department (ed) - roper hospital - weekend only

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 36 Work Shift: Days (United States of America) Primary Function/General Purpose of Position To provide...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    23 days ago

    Registered nurse (rn) - emergency department (ed) - roper hospital - prn

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 0.01 Work Shift: Rotating Shifts (United States of America) Summary of Primary Function Delivers patient...

    onsite, Charleston, SC, United States
    Part TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (fall 2026 new grad blitz) - main 9c short stay

    Job Description Summary Located at MUSC Health’s main hospital, 9 Center is a nine-bed ER overflow, Admission and Holding unit open 24/7. 9Center is designed to help alleviate boarding in the...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (fall 2026 new grad blitz) - 7e medical acute care

    Job Description Summary 7East Medical Acute Care Unit is a 26-bed inpatient Medical-Surgical Unit which provides care to an adult and geriatric patient population. 7East is identified as the...

    onsite, Charleston, SC, United States
    $44k/yrFull TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (fall 2026 new grad blitz) - 8d eh acute care

    Job Description Summary Located at MUSC Health’s extension hospital, 8D EH is a 13-bed inpatient adult acute med-surg unit open 24/7. 8D EH is designed to accommodate medical and surgical patients...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad ) - 9c short stay

    Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad) - 7e medical acute care

    Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad) - 6w surgical/trauma burn intermediate care- new grad

    Job Description Summary 6W Care Team Members provide care for burn patients. At times, these patients need to go to the hydrotherapy room in the SBICU. The SBICU nurses do not provide the...

    onsite, Charleston, SC, United States
    $73k/yrFull TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse (rn) musc leatherman adolescent inpatient prn

    Job Description Summary Awesome PRN opportunity for an experienced nurse interested in Behavioral Health! Apply today or contact Recruiter Shannon Shaw at shawsh@musc.edu or 843-674-2694 for more...

    onsite, Charleston, SC, United States
    Part TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad) - 7a family medicine

    Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles...

    onsite, Charleston, SC, United States
    Full TimeJunior (<2 years)
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad) - art vascular operating room

    Job Description Summary Ashley River Tower (ART) perioperative services are located on the fourth floor of the ART building. The ART PACU is a 12-bed unit that provides post-operative care for a...

    onsite, Charleston, SC, United States
    $52k/yrFull TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new grad) - rutledge tower or

    Job Description Summary Rutledge Tower Ambulatory Surgery consists of 9 OR's for adult outpatient and inpatient populations. Ambulatory Service Groupings are ENT, Oral Surgery, Adult Dentistry,...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Medical University of South Carolina

    Medical University of South Carolina

    24 days ago

    Registered nurse i (new graduate) - art 6w acute care

    Job Description Summary Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and...

    onsite, Charleston, SC, United States
    Full TimeEntry with Degree
  • Veterans Health Administration

    Veterans Health Administration

    a month ago

    Nurse manager - community care

    Summary This vacancy is for a Nurse Manager (RN) in the Community Care department at the Charleston VA Medical Center. Duties Designated first-line supervisory authority. Responsible/accountable for...

    onsite, Charleston, SC, United States
    $88k/yrFull TimeMiddle (2-4 years)
  • ComForCare Home Health Care - Charleston SC

    ComForCare Home Health Care - Charleston SC

    a month ago

    Part-time caregiver for weekends/ 5-10 hour shifts

    Benefits: Opportunity for advancement Training & development Bonus based on performance Competitive salary Locations: Meggett, Hollywood, Johns Island, and Charleston, SC Schedule: Weekends |...

    onsite, Charleston, SC, United States
    Part TimeJunior (<2 years)
  • Roper St. Francis Healthcare

    Roper St. Francis Healthcare

    a month ago

    Registered nurse (rn) weekend only – cardiothoracic and vascular intermediate care – roper hospital

    Thank you for considering a career at Roper St. Francis Healthcare! Scheduled Weekly Hours: 36 Work Shift: Nights (United States of America) Summary of Primary Function Delivers patient care...

    onsite, Charleston, SC, United States
    Full TimeMiddle (2-4 years)

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