Position Summary

The Santi lab is seeking a motivated and detail-oriented Senior Research Technician to join a laboratory investigating sperm physiology, biomarkers of male infertility, and the development of novel contraceptive approaches.

Our research focuses on understanding the cellular and molecular mechanisms that regulate sperm function and fertility. The successful candidate will participate in studies examining sperm membrane physiology, intracellular calcium signaling, membrane potential, sperm motility, infertility-associated biomarkers, and the effects of candidate compounds on sperm function.

The technician will be trained in fluorescence-based assays using voltage- and calcium-sensitive fluorescent indicators, plate-reader measurements, quantitative sperm motility assays, and data-analysis approaches. The position will also involve evaluating candidate molecules and pharmacological interventions for their potential effects on sperm function and their potential utility in the development of novel contraceptive strategies.

This position is particularly suited to an individual who enjoys hands-on laboratory research, is highly attentive to experimental detail, has strong quantitative skills, and is interested in translating basic discoveries in reproductive physiology into approaches relevant to infertility diagnosis and contraceptive development.

Primary Duties & Responsibilities

• Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians.
• Enters data and maintains current data files on research projects. Monitors data to ensure consistent quality.
• May perform preliminary statistical analysis of data.
• Prepares figures, tables, and summaries for laboratory meetings, presentations, manuscripts, and grant-related activities.
• Reads and discusses relevant scientific literature.
• Troubleshoots experimental procedures and contributes to improving assay reproducibility.
• Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
• Assists in the training and development of technicians, acting as a group leader.
• Performs other duties as assigned.

Working Conditions

Works in a laboratory environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and to provide standard care to research animals.

Required Qualifications

Education:

Master’s degree or combination of education and/or experience may substitute for minimum education.

Certifications/Professional Licenses:

No specific certification/professional license is required for this position.

Work Experience:

Laboratory Setting (1 Year)

Preferred Qualifications

Research experience involving sperm biology, reproductive physiology, male infertility, cellular physiology, pharmacology, or fluorescence-based assays. Experience with GraphPad Prism, R, Python, MATLAB, or comparable data-analysis software.

Salary Range

$18.77 - $31.94 / Hourly

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Benefits Statement

Personal: Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Take advantage of our free Metro transit U-Pass for eligible employees. WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Family: We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered. WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.