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  2. Mississippi
  3. Registered Nurse

Onsite Registered Nurse jobs in Mississippi, USA

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Registered Nurse Jobs in Mississippi — On-Site Opportunities Await

Healthcare providers across Mississippi are actively hiring for registered nurse on-site jobs to meet growing patient care demands. With 500+ open positions available, this role offers a chance to deliver hands-on care within local hospitals and clinics. The state's expanding healthcare network continues to create strong opportunities for dedicated nurses.

Successful candidates typically hold an active RN license, strong clinical assessment skills, and a compassionate bedside manner. Employers value nurses proficient in electronic health records, medication administration, and patient education, along with clear communication across interdisciplinary teams. Adaptability to varying shifts and genuine dedication to patient outcomes help candidates stand out among registered nurse vacancies.

On-site registered nurse opportunities in Mississippi involve direct patient interaction within hospitals and clinics, requiring hands-on presence to deliver timely care. The state's healthcare sector keeps expanding, driven by an aging population and broader access to care statewide. This steady demand makes now an ideal time to explore openings with strong growth potential.

Whether you're starting your nursing career or seeking a new opportunity, now is the time to explore registered nurse openings that match your goals. Global Work AI connects skilled professionals with employers ready to grow their care teams across Mississippi. Take the next step in your journey today.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average registered nurse salary in Mississippi, and what factors affect pay by facility or specialty?

    In Mississippi, a registered nurse salary often falls below the national average, with many full-time roles landing in the mid-$60,000s to low-$70,000s annually, depending on experience and setting. Large hospitals, specialty units, and higher-acuity departments such as ICU, emergency, or perioperative care may pay more than long-term care or outpatient clinics. Shift differentials, certification status, weekend coverage, and years of clinical practice can also raise earnings. Reviewing current Mississippi listings helps you compare pay across employers, benefits, and specialty demand.
  • What qualifications are needed to become a registered nurse in Mississippi?

    Most employers in Mississippi look for an accredited nursing degree, commonly an Associate Degree in Nursing or a Bachelor of Science in Nursing, along with successful completion of the NCLEX-RN. Clinical rotations are a standard part of preparation because they build hands-on experience in patient care. A strong academic record helps, but hospitals and clinics also value prior exposure to med-surg, acute care, or community health. Some facilities prefer BSN-prepared candidates, especially for leadership tracks, so it can help to compare openings by education level and unit type.
  • Is an active RN license required for registered nurse jobs, and how do I transfer an out-of-state license to Mississippi?

    Yes, an active RN license is required for most registered nurse jobs in Mississippi, and employers typically verify licensure before onboarding. If your license was issued in another state, the Mississippi Board of Nursing usually handles endorsement for qualified applicants. That process generally includes proof of current licensure, verification of education, fingerprints or background screening, and any required fees. Rules can change, especially if your former state is part of the Nurse Licensure Compact, so checking board requirements early can save time before applying.
  • What are the main responsibilities of a registered nurse in an on-site hospital or clinic role?

    In an on-site hospital or clinic setting, a registered nurse usually monitors patient status, gives prescribed medications, documents care, and coordinates with physicians, therapists, and support staff. Day-to-day duties can include intake assessments, wound care, IV support, discharge teaching, and responding to changes in condition. In Mississippi facilities, the scope may vary by unit, such as med-surg, pediatrics, or ambulatory care. Strong communication and safe clinical judgment are essential, and many employers post role details so candidates can match duties with the right environment.
  • What skills are most important for a registered nurse, including medication administration, patient assessment, and charting?

    Success in registered nurse work depends on more than technical knowledge. Safe medication administration, accurate patient assessment, and thorough charting are core skills, but employers in Mississippi also look for clear communication, time management, and calm decision-making under pressure. Familiarity with electronic health records is especially valuable in hospitals and clinics, where documentation must be timely and precise. Infection control, teamwork, patient education, and prioritization also matter. If you are comparing openings, notice which units emphasize bedside care, fast-paced triage, or long-term care duties.
  • What does the hiring process for registered nurse jobs in Mississippi usually include, such as interviews, background checks, and skills tests?

    The hiring process for registered nurse roles in Mississippi often begins with an application review, followed by one or more interviews with nurse managers or HR. Many employers then complete license verification, reference checks, drug screening, and a criminal background check before extending an offer. Some hospital systems also use skills assessments, scenario-based questions, or competency reviews for specialties like ICU or emergency care. If the position is on-site, onboarding may include health clearance and orientation. Watching for these steps in listings can help you prepare in advance.
  • What are the typical shift schedules and career growth opportunities for a registered nurse in Mississippi?

    Shift options for a registered nurse in Mississippi often include 12-hour days or nights, eight-hour clinic schedules, rotating weekends, and holiday coverage in hospital settings. Acute care facilities may offer more shift variety, while outpatient and physician offices usually follow weekday hours. Career growth can move from bedside roles into charge nurse, preceptor, case management, quality improvement, or nurse leadership positions. Specialty certifications and a BSN may open additional paths. Comparing schedules and advancement options across Mississippi employers can help you find a role that fits both lifestyle and long-term goals.

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500+ jobs found

  • Singing River Health System

    Singing River Health System

    Today

    Registered nurse (rn) | full time | nights - 1/2se surgical nursing - ortho/neuro

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Full TimeJunior (<2 years)
  • Community Health Systems Professional Services Corporation

    Community Health Systems Professional Services Corporation

    Today

    Registered nurse icu prn - seasonal contract

    Why Merit Health? Choosing a career is about more than finding a job, it's about joining a team where you are respected, valued, and supported. At Merit Health, your work has a meaningful impact,...

    onsite, Hattiesburg, MS, United States
    Part TimeJunior (<2 years)
  • UHS

    UHS

    a day ago

    Registered nurse (prn)- nights

    Responsibilities Parkwood Behavioral Health System (a UHS facility): Parkwood Behavioral Health System provides behavioral health and chemical dependency services to the Mid-South region and has been...

    onsite, Desoto County, MS, United States
    Part TimeJunior (<2 years)
  • Millcreek of Magee

    Millcreek of Magee

    2 days ago

    Registered nurse (rn) - mon-fri 3pm-11pm $32 hour

    Overview PURPOSE STATEMENT: Clinical professional is responsible for facilitating admissions, clinical intake assessments, and utilization review processes to assure continuity for the most...

    onsite, Magee, MS, United States
    $65k/yrFull TimeJunior (<2 years)
  • The Pillars

    The Pillars

    2 days ago

    Registered nurse (rn)

    The Pillars of Biloxi is looking for a Registered Nurse (RN) to join our growing team! Are you a highly skilled, caring, and compassionate Registered Nurse (RN) looking for a rewarding career with...

    onsite, Biloxi, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    2 days ago

    Registered nurse (rn) | full time | operating room

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Ocean Springs, MS, United States
    Full TimeJunior (<2 years)
  • Sunplex Subacute Center

    Sunplex Subacute Center

    3 days ago

    Registered nurse (rn)- prn

    If you are a highly skilled, caring, compassionate Registered Nurse (RN) (PRN) seeking employment with unparalleled benefits and growth opportunities, look no further! Begin your career at Sunplex...

    onsite, Ocean Springs, MS, United States
    Full TimeJunior (<2 years)
  • FMOLHS

    FMOLHS

    3 days ago

    Registered nurse 2 wow - med surg neurology (nights)

    Weekender must work every Fri, Sat, Sun. Increase hourly pay for WOW position. Coordinates and delivers patient care using the health care team philosophy practice model. Coordinates and does patient...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Memorial Hospital at Gulfport

    Memorial Hospital at Gulfport

    6 days ago

    Registered nurse - medical telemetry - days - wknd

    Job Summary: Under the direct supervision of the physician(s) in the clinic, this position provides professional nursing care to all patient populations. Works with team members and providers to...

    onsite, Gulfport, MS, United States
    Full TimeEntry with Degree
  • UHS

    UHS

    6 days ago

    Intake/admissions registered nurse (rn)

    Responsibilities Registered Nurse (RN) Opportunity – Weekend Night Shifts. This position is eligible for our $15,000.00 sign-on bonus! New grads are welcome to apply! Brentwood Behavioral Healthcare...

    onsite, Flowood, MS, United States
    $30k/yrFull TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    7 days ago

    Registered nurse, full time days

    Start your next chapter at Bolivar Medical Center, a 164-bed hospital serving Cleveland, MS, and part of the ScionHealth community hospital network. Bolivar Medical Center is a Joint Commission...

    onsite, Cleveland, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    8 days ago

    Registered nurse (rn) | full time | days - cv operating room

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Ocean Springs, MS, United States
    Full TimeJunior (<2 years)
  • VitalCore Health Strategies

    VitalCore Health Strategies

    8 days ago

    Registered nurse (rn)

    Join the VitalCore Team! We’re people who are fueled by passion, not by profit. VitalCore Health Strategies (VCHS), an industry leader in Correctional Health Care has openings for Registered Nurses...

    onsite, Parchman, MS, United States
    Part TimeJunior (<2 years)
  • Community Health Systems Professional Services Corporation

    Community Health Systems Professional Services Corporation

    8 days ago

    Registered nurse - pacu - advanced surgical care - prn

    Why Join Us? Be Valued for What You Bring to the Team – Competitive pay that rewards your hard work Benefits You Can Count On – Medical, dental, vision, and life insurance coverage Work Hard....

    onsite, Flowood, MS, United States
    Part TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    9 days ago

    Registered nurse (rn) | part time | nights - nursery

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Ocean Springs, MS, United States
    Part TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    9 days ago

    Registered nurse (rn) | part time | operating room

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Gulfport, MS, United States
    Part TimeJunior (<2 years)
  • Community Health Systems Professional Services Corporation

    Community Health Systems Professional Services Corporation

    10 days ago

    Registered nurse- seasonal contract orthopedic prn nights

    Why Merit Health? Choosing a career is about more than finding a job, it's about joining a team where you are respected, valued, and supported. At Merit Health, your work has a meaningful impact,...

    onsite, Hattiesburg, MS, United States
    Part TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    12 days ago

    Registered nurse (rn) | part time | nights - emergency room services

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Gulfport, MS, United States
    Part TimeJunior (<2 years)
  • Pleasant Hills Community Living Center

    Pleasant Hills Community Living Center

    13 days ago

    Registered nurse (rn)- day & evening

    If you are a highly skilled, caring, compassionate Registered Nurse (RN) seeking employment with unparalleled benefits and growth opportunities, look no further! Begin your career at Pleasant Hills...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    15 days ago

    Registered nurse (rn) | part time | rotating shifts - nursery

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Ocean Springs, MS, United States
    Part TimeJunior (<2 years)
  • Methodist Le Bonheur Healthcare

    Methodist Le Bonheur Healthcare

    15 days ago

    Registered nurse (rn) | icu - pediatrics | multiple locations

    If you are looking to make an impact on a meaningful scale, come join us as we embrace the Power of One! We strive to be an employer of choice and establish a reputation for being a talent rich...

    onsite, Germantown, TN, United States
    Full TimeJunior (<2 years)
  • Methodist Le Bonheur Healthcare

    Methodist Le Bonheur Healthcare

    16 days ago

    Registered nurse (rn) | icu - adults | multiple locations

    If you are looking to make an impact on a meaningful scale, come join us as we embrace the Power of One! We strive to be an employer of choice and establish a reputation for being a talent rich...

    onsite, Germantown, TN, United States
    Full TimeJunior (<2 years)
  • Methodist Rehabilitation

    Methodist Rehabilitation

    16 days ago

    Registered nurse (rn) - 11-7 shift - long term care

    Job Details: Level: Experienced Job Location: Layfair MSCC Campus - Flowood, MS Position Type: Full Time Education Level: 2 Year Degree Salary Range: Undisclosed Job Shift: Third Shift (11:00 p.m. -...

    onsite, Flowood, MS, United States
    Full TimeJunior (<2 years)
  • FMOLHS

    FMOLHS

    16 days ago

    Registered nurse 2 wow - labor & delivery (days)

    Weekender must work every Fri, Sat, Sun. Increase hourly pay for WOW position. Coordinates and delivers patient care using the health care team philosophy practice model. Coordinates and does patient...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Community Health Systems Professional Services Corporation

    Community Health Systems Professional Services Corporation

    20 days ago

    Registered nurse icu prn

    Why Merit Health? Choosing a career is about more than finding a job, it's about joining a team where you are respected, valued, and supported. At Merit Health, your work has a meaningful impact,...

    onsite, Vicksburg, MS, United States
    Part TimeJunior (<2 years)
  • FMOLHS

    FMOLHS

    20 days ago

    Registered nurse 2 wow

    Weekender must work every Fri, Sat, Sun. Increase hourly pay for WOW position. Coordinates and delivers patient care using the health care team philosophy practice model. Coordinates and does patient...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Methodist Rehabilitation

    Methodist Rehabilitation

    21 days ago

    Registered nurse (rn) - outpatient rehabilitation clinic

    Job Details: Level: Experienced Job Location: Main Campus - Inpatient - Jackson, MS Position Type: Full Time Education Level: 2 Year Degree Salary Range: Undisclosed Job Shift: Day Job Category:...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Methodist Rehabilitation

    Methodist Rehabilitation

    21 days ago

    Registered nurse (rn) - 7-3 shift - spinal cord injury

    Job Details: Level: Experienced Job Location: Main Campus - Inpatient - Jackson, MS Position Type: Full Time Education Level: 2 Year Degree Salary Range: Undisclosed Job Shift: First Shift (7:00 a.m....

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Methodist Rehabilitation

    Methodist Rehabilitation

    21 days ago

    Registered nurse (rn) - prn - long term care

    Job Details: Level: Experienced Job Location: Layfair MSCC Campus - Flowood, MS Position Type: PRN Education Level: 2 Year Degree Salary Range: Undisclosed Job Shift: Any Job Category: Nurse,...

    onsite, Flowood, MS, United States
    Part TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    21 days ago

    Registered nurse (rn) | full time | days - medical icu

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    21 days ago

    Registered nurse (rn) | full time | nights - medical icu

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    21 days ago

    Registered nurse (rn) | full time | nights - proressive care unit

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Full TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    21 days ago

    Registered nurse (rn) | part time | days and nights - skilled nursing facility

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Part TimeJunior (<2 years)
  • Singing River Health System

    Singing River Health System

    21 days ago

    Registered nurse (rn) | full time | mids - emergency room services

    At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy,...

    onsite, Pascagoula, MS, United States
    Full TimeMiddle (2-4 years)
  • Ochsner Health

    Ochsner Health

    22 days ago

    Registered nurse (rn) - critical care - nights

    Exceptional care starts with exceptional people. For us, this is more than a job– it’s a calling. It’s waking up each day, looking for ways to make a difference with a compassionate, inclusive and...

    onsite, Bay St. Louis, MS, United States
    Full TimeEntry with Degree
  • UHS

    UHS

    25 days ago

    Registered nurse (rn) - nights

    Responsibilities Gulfport Behavioral Health System (a UHS facility): Gulfport Behavioral Health System, is a 92-bed psychiatric hospital offering child, adolescent, adult and military service...

    onsite, Gulfport, MS, United States
    Full TimeJunior (<2 years)
  • Methodist Rehabilitation

    Methodist Rehabilitation

    a month ago

    Registered nurse (rn) - 3-11 shift - brain injury unit

    Job Details: Job Location: Main Campus - Inpatient - Jackson, MS Position Type: Full Time Education Level: 2 Year Degree Salary Range: Undisclosed Job Shift: Swing Shift (3:00 p.m. - 11:00 p.m.) Job...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • FMOLHS

    FMOLHS

    a month ago

    Registered nurse 2 - cardiac 2 (nights)

    Coordinates and delivers patient care using the health care team philosophy practice model. Coordinates and does patient teaching and discharge planning. Coordinates activities with ancillary...

    onsite, Jackson, MS, United States
    Full TimeJunior (<2 years)
  • Simpson General Hospital

    Simpson General Hospital

    a month ago

    Registered nurse (rn) – emergency department - days

    Registered Nurse (RN) – Emergency Department Location: Mendenhall, MS Commitment: Full Time | 12-Hour Shifts | 7:00am - 7:00pm Reports to: RN Supervisor & Director of Nursing At Simpson General...

    onsite, Mendenhall, MS, United States
    Full TimeJunior (<2 years)
  • Simpson General Hospital

    Simpson General Hospital

    a month ago

    Registered nurse (rn) – emergency department - nights

    Registered Nurse (RN) – Emergency Department (Full Time) Mendenhall, MS Full Time | 12-Hour Shifts | 7:00pm - 7:00am Reports to: RN Supervisor & Director of Nursing At Simpson General Hospital (SGH),...

    onsite, Mendenhall, MS, United States
    Full TimeJunior (<2 years)

10,000,000+ more jobs available!