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  4. Registered Nurse

Onsite Registered Nurse jobs in Louisville, Kentucky, USA

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      Alex Chen

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      David G. (Hiring Manager)

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      Sophie L.

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      Marta W.

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      James Miller

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      Chris V.

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Registered Nurse Jobs in Louisville — On-Site Opportunities Await

Louisville's healthcare network continues to grow, creating a steady need for skilled nursing professionals. Hospitals and clinics across the city are actively looking to fill 317 on-site registered nurse positions, reflecting strong regional demand for compassionate, skilled bedside care. Anyone searching for registered nurse jobs in Louisville will find a market rich with opportunity and purpose.

Successful candidates typically bring strong clinical judgment, patient assessment skills, and the ability to collaborate effectively within multidisciplinary teams. Employers value registered nurses who demonstrate excellent communication, time management, and a calm, adaptable approach to high-pressure situations. Proficiency with electronic health records, medication administration, and evidence-based practice remains essential, while a genuine commitment to patient advocacy sets top applicants apart.

On-site registered nurse roles in Louisville typically involve full shift coverage within hospital units, outpatient clinics, or long-term care facilities, allowing for hands-on patient interaction and immediate care coordination. Kentucky's healthcare sector has seen consistent growth, and local employers are eager to hire a registered nurse who can adapt quickly to fast-paced clinical environments. This steady demand makes Louisville an appealing hub for nursing careers.

If you're ready to take the next step in your nursing career, now is the time to explore current registered nurse vacancies in Louisville. Global Work AI connects dedicated professionals with healthcare employers seeking passionate, reliable talent. Discover your next opportunity and join a community shaping the future of patient care.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average registered nurse salary in Louisville?

    In Louisville, Kentucky, pay for a registered nurse usually falls in the mid-to-upper range for the region, often landing around the low-to-mid $70,000s per year, with variation based on unit, years of practice, and specialty. Hospital roles, charge nurse duties, and night or weekend rotations can push earnings higher, while entry-level positions may start lower. Local pay also shifts with demand at major health systems and outpatient centers in the Louisville area. Reviewing current postings is the best way to compare base pay, differentials, and total compensation.
  • What qualifications do I need to apply for a registered nurse job in Louisville?

    Most employers in Louisville look for an accredited nursing degree, typically an ADN or BSN, plus successful completion of the NCLEX-RN. Clinical rotations in acute care, med-surg, critical care, or outpatient settings are commonly valued, especially if they align with the unit’s patient population. Some facilities may prefer a BSN or prior hospital experience, while others will consider new graduates with strong clinical references. If you are comparing openings in Kentucky, it helps to note any specialty training, certifications, and education requirements listed in each posting.
  • Is a current Kentucky RN license required for this on-site registered nurse position?

    For an on-site registered nurse role in Louisville, employers generally expect an active Kentucky RN license or eligibility to obtain one quickly. Facilities cannot usually place you in direct patient care without the appropriate state authorization, even if you already hold a license from another state. Some organizations may accept a compact license if your home state is part of the Nurse Licensure Compact and you meet Kentucky practice rules. Since requirements can vary by employer and patient setting, it is smart to verify licensure details against the current listing before applying.
  • What are the main responsibilities of a registered nurse in an on-site hospital or clinic setting?

    Day-to-day work often centers on assessing patients, giving medications, monitoring vital signs, and coordinating care with physicians and other clinicians. In a Louisville hospital or clinic, a registered nurse may also document treatment, prepare patients for procedures, educate families, and respond to changes in condition. Depending on the unit, duties can include wound care, IV therapy, discharge planning, and handling urgent situations. Because each facility has its own workflow, reviewing the posting can help you see whether the role fits a bedside, ambulatory, or specialty care environment.
  • What skills and clinical experience do employers look for in a registered nurse?

    Hiring teams usually want strong assessment ability, safe medication administration, clear communication, and calm decision-making under pressure. In Louisville, experience with electronic health records, interdisciplinary teamwork, and patient education is especially useful in hospital and clinic environments. Many employers also value exposure to telemetry, med-surg, emergency care, perioperative support, or other specialty areas, depending on the opening. Soft skills matter too: empathy, organization, and attention to detail can set candidates apart. Comparing postings side by side can help you match your background to the most relevant clinical setting.
  • What does the hiring process look like for a registered nurse position in Louisville?

    The process usually starts with an application review, followed by a recruiter screen or phone interview, then one or more conversations with nursing leadership. Many Louisville employers also verify education, licensure, references, immunizations, background checks, and sometimes drug screening before extending an offer. For hospital-based roles, you may be asked about patient scenarios, shift flexibility, and unit experience. Timelines vary by organization, but strong candidates often move quickly once credentials are confirmed. Checking each employer’s steps can help you prepare documents and compare similar openings more efficiently.
  • What shift schedules and benefits are common for registered nurse jobs?

    Schedules in Louisville often include day, evening, night, weekend, and holiday rotations, with some facilities offering 8-, 10-, or 12-hour shifts. Acute care employers may provide differentials for nights or weekends, while clinics and outpatient sites can lean toward more standard weekday hours. Benefits commonly include health coverage, retirement plans, paid time off, tuition support, and continuing education assistance. Some organizations also add sign-on bonuses, certification reimbursement, or flexible scheduling. Since benefits packages differ widely, it helps to review each listing closely and compare the full offer, not just the base pay.

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317 jobs found

  • Venza Care Management

    Venza Care Management

    a day ago

    Assistant director of nursing ( adon )

    Are you a compassionate and skilled nurse leader looking to take on an essential role in delivering top-quality care? Do you thrive in a dynamic environment where you can mentor and support a team of...

    onsite, Louisville, KY, United States
    $90k – $110k/yrFull TimeEntry with Degree
  • Seven Counties Services

    Seven Counties Services

    a day ago

    Registered nurse or licensed practical nurse - outpatient prn

    Job Description: ESSENTIAL JOB FUNCTIONS Administers and oversees self-administered and prescribed medications per established schedules as ordered. Monitors clients' vital signs and other physical...

    onsite, Louisville, KY, United States
    Part TimeSenior (5+ years)
  • DAVITA

    DAVITA

    2 days ago

    Registered nurse

    Posting Date 10/19/2026 720 W Broadway, Louisville, Kentucky, 40202, United States of America Make a real impact—every day. As a DaVita RN, you’ll ensure compassionate and professional delivery of...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    2 days ago

    Glenmary freestanding emergency department registered nurse prn days

    Summary Job Description: Registered Nurse, Glenmary Freestanding Emergency Department- PRN, Days Status: PRN Shift: First Job Summary Registered nurse implements the nursing process for each assigned...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • Signature HealthCARE, LLC

    Signature HealthCARE, LLC

    2 days ago

    Rn supervisor

    About Us Signature HealthCARE at Rockford Rehab & Wellness Center is a 110-bed facility that offers a wide array of services from short-term rehabilitation to traditional long-term care. It is our...

    onsite, Louisville, KY, United States
    $93k/yrFull TimeJunior (<2 years)
  • Signature HealthCARE, LLC

    Signature HealthCARE, LLC

    2 days ago

    Registered nurse (rn)

    About Us Signature HealthCARE of South Louisville is a 100-bed facility offering a broad range of services, from short-term and long-term skilled care and intermediate care to inpatient and...

    onsite, Louisville, KY, United States
    $90k/yrFull TimeJunior (<2 years)
  • BHS

    BHS

    2 days ago

    Lactation registered nurse full time nights

    Summary Job Description: Lactation Registered Nurse- Full Time, Nights Status: Full Time Shift: Third Job Summary: The lactation consultant is a member of the Mother-Baby team who provides...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    2 days ago

    Registered nurse nicu part time nights

    Summary Job Description: Registered Nurse NICU- Part Time, Nights Status: Part Time Shift: Third About the Unit: The NICU provides level III care to infants as early as 26 weeks gestation. NICU is...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • BHS

    BHS

    2 days ago

    Registered nurse nicu prn nights

    Summary Job Description: Registered Nurse NICU- PRN, Nights Status: PRN Shift: Third About the Unit: The NICU provides level III care to infants as early as 26 weeks gestation. NICU is comprised of...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • Lifepoint Health

    Lifepoint Health

    3 days ago

    Registered nurse, rehabilitation

    Join our Remarkable Team! Location – Louisville, KY Schedule – Full Time Days 7a-7p Your experience matters U of L Rehab Hospital Frazier Brownsboro is part of Lifepoint Health, a diversified...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    3 days ago

    Experienced surgical registered nurse full time day shift

    Summary Job Description: Join Our Skilled Surgical Team! At Baptist Health Louisville, we provide a full scope of surgical services (excluding organ transplants) across multiple specialties,...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • UofL Health

    UofL Health

    8 days ago

    Rn npd, jewish hospital, cath lab

    Primary Location: JHHS - Jewish Hospital - UMC Address: 200 Abraham Flexner Way Louisville, KY 40202 Shift: First Shift (United States of America) Job Description Summary: UofL Health is a fully...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • New Vista of the Bluegrass Inc

    New Vista of the Bluegrass Inc

    8 days ago

    Case manager-rn

    Join our team and experience the work atmosphere you have always wanted to be a part of! We offer realistic patient caseloads that result in a reasonable workflow. This practice will allow you to...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Home of the Innocents

    Home of the Innocents

    8 days ago

    Rn, house supervisor - part-time

    Are you a clinical leader who thrives in high-acuity settings and knows how to keep a team steady when things get complex? Home of the Innocents is seeking an RN House Supervisor to serve as the...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • Signature HealthCARE, LLC

    Signature HealthCARE, LLC

    9 days ago

    Hiring event - registered nurse (rn)

    About Us Signature HealthCARE at Summerfield Rehab & Wellness Center is a 165-bed facility that offers a wide array of services from short-term rehabilitation to traditional long-term care. It is our...

    onsite, Louisville, KY, United States
    $90k/yrFull TimeJunior (<2 years)
  • Fresenius Medical Care

    Fresenius Medical Care

    10 days ago

    Dialysis clinical manager registered nurse - rn

    About this role: As a Clinical Manager with Fresenius Medical Care, you will ensure that quality patient care is delivered while maintaining clinical operations. As the facility leader, you will be...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • DaVita Kidney Care

    DaVita Kidney Care

    10 days ago

    Registered nurse

    Posting Date 10/19/2026 720 W Broadway, Louisville, Kentucky, 40202, United States of America Make a real impact—every day. As a DaVita RN, you’ll ensure compassionate and professional delivery of...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Venza Care Management

    Venza Care Management

    10 days ago

    Registered nurse (rn) unit manager

    Are you a dedicated and experienced Registered Nurse (RN) with a passion for leading and supporting a clinical team? Do you excel in a leadership role where you can make a significant impact on...

    onsite, Louisville, KY, United States
    $75k – $85k/yrFull TimeJunior (<2 years)
  • TRITAL Care

    TRITAL Care

    11 days ago

    Registered nurse (rn) - prn

    About the Role We are seeking qualified Registered Nurses for PRN assignments across multiple hospital units and clinical specialties in Louisville, Kentucky. Nurses will provide patient-centered...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    12 days ago

    Registered nurse full-time nights

    Job Summary Provides planning and delivery of direct and indirect patient care through the nursing process of Assessment, Planning, Intervention, and Evaluation. Develops nursing care plans in...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Volunteers of America National Services

    Volunteers of America National Services

    12 days ago

    Nurse practitioner

    Care with Heart. Work with Purpose. Join The Senior Community Care of Kentucky PACE as a Nurse Practitioner in Louisville, KY (Jefferson County). This is more than a job! It’s a paid opportunity to...

    onsite, Louisville, KY, United States
    $118k – $134k/yrFull TimeJunior (<2 years)
  • BHS

    BHS

    12 days ago

    Registered nurse nicu full time nights

    Summary Job Description: Registered Nurse NICU- Full Time, Nights Status: Full Time Shift: Third About the Unit: The NICU provides level III care to infants as early as 26 weeks gestation. NICU is...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • UofL Health

    UofL Health

    13 days ago

    Rn npd iii, or

    Primary Location: UofL Hospital - UMC Address: 530 South Jackson Street Louisville, KY 40202 Shift: Job Description Summary: About UofL Health: UofL Health is a fully integrated regional academic...

    onsite, Louisville, KY, United States
    Full TimeMiddle (2-4 years)
  • BHS

    BHS

    13 days ago

    Registered nurse women's health full time nights

    Summary Job Description: Registered Nurse Women's Health- Full Time, Nights Status: Full Time Shift: Third About the Unit: The Women’s Health Unit is a 24 bed all private room unit solely for women....

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Fresenius Medical Care

    Fresenius Medical Care

    14 days ago

    Acute inpatient registered nurse - rn - dialysis

    PLEASE NOTE LOCATIONS WILL INCLUDE: U of L Health - Jewish Hospital: 225 Abraham Flexner Way, Louisville, KY 40202 U of L Health - Mary & Elizabeth Hospital: 1850 Bluegrass Ave, Louisville, KY 40215...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Trilogy Health Services, LLC

    Trilogy Health Services, LLC

    14 days ago

    Registered nurse (rn)

    JOIN TEAM TRILOGY At Trilogy, you’ll experience a caring, supportive community that values each team member. We prioritize meaningful relationships, genuine teamwork, and continuous growth. With the...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    14 days ago

    Registered nurse, ft nights

    Kindred Hospital Louisville is a 123-bed long-term acute care hospital offering the same in-depth care you would receive in a traditional hospital, but for an extended recovery period; including 16...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Innovative Renal Care

    Innovative Renal Care

    15 days ago

    Dialysis registered nurse

    Job Requirements Our Registered Nurses provide high quality patient care to patients suffering from the most advanced stage of chronic kidney disease, known as End Stage Renal Disease (ESRD). Nurses...

    onsite, Louisville, KY, United States
    $81k – $105k/yrFull TimeJunior (<2 years)
  • Adelphi Staffing

    Adelphi Staffing

    15 days ago

    Rn - pcu/tele

    JOB OVERVIEW Job Title: RN – PCU/Tele Profession: RN Specialty: PCU/Telemetry Job Type: Contract Location: Louisville, KY Schedule: 6:45 AM – 7:15 PM, 12-hour day shifts Weekends/Holidays: Every...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    19 days ago

    Registered nurse labor and delivery full time nights

    Summary Job Description: Registered Nurse Labor & Delivery- Full Time, Nights Status: Full Time Shift: Third Employment Bonus Available for Eligible Applicants About The Unit: The Labor and Delivery...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    19 days ago

    Orthopedic post surgical telemetry registered nurse full time nights

    Summary Job Description: Full Time 36 weekly hours, night shift Sign On Bonus Eligible for experienced candidates! About the Unit: Baptist Louisville has two 24 bed all private room Orthopedic units....

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Lifepoint Health

    Lifepoint Health

    21 days ago

    Registered nurse, (rn) rehabilitation (ft nights)

    Join our Remarkable Team! Location – Louisville, KY Schedule – Full Time Nights 7p-7a Your experience matters U of L Rehab Hospital Frazier Brownsboro is part of Lifepoint Health, a diversified...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    23 days ago

    Registered nurse labor and delivery full time nights *sign-on bonus eligible*

    Summary Job Description: Registered Nurse Labor and Delivery- Full Time, Nights Status: Full Time Shift: Third Sign-on Bonus for Eligible Applicants Are you ready to take next step in your nursing...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Isaiah House Inc

    Isaiah House Inc

    24 days ago

    Registered nurse - prn

    Come for the career. Stay for the mission. Change lives along the way. Isaiah House is a nonprofit, Christ-centered addiction recovery organization serving individuals and families across Kentucky....

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • BHS

    BHS

    a month ago

    Intensive care registered nurse prn days

    Summary 3- 12 hour shift coverage every 6 weeks Job Description: PRN, Days About the Unit: The Intensive Care unit (ICU) is a 20 bed critical care unit specializing in neurologic care. Staff working...

    onsite, Louisville, KY, United States
    Part TimeJunior (<2 years)
  • BHS

    BHS

    a month ago

    Intensive care registered nurse full time days

    Summary 3x12 hrs Job Description: Full Time 36 weekly hours, day shift - three 12-hour shifts per week (7a to 7p) & every third weekend. Support shifts required. Sign On Bonus Eligible for...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    a month ago

    Registered nurse nicu full time wow lite nights

    Summary Job Description: Registered Nurse NICU- Full Time, WOW Lite, Nights Status: Full Time Shift: Third Every other weekend required About the Unit: The NICU provides level III care to infants as...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • BHS

    BHS

    a month ago

    Registered nurse cardiovascular unit full time weekend nights

    Summary Job Description: Seeking Registered Nurse for Cardiovascular Unit! Full Time, Nights (7p-7a - every weekend) Bonus Eligible for Qualified Candidates Join our team in the Cardiovascular Unit...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)
  • Abode Care Partners

    Abode Care Partners

    a month ago

    Director of care management - registered nurse - rn

    Our Company Abode Care Partners Overview As the Director of Care Management, you will play a pivotal role in ensuring the delivery of high-quality patient care and effective care coordination within...

    onsite, Louisville, KY, United States
    $110k – $130k/yrFull TimeDirector
  • UofL Health

    UofL Health

    a month ago

    Rn, uofl hospital, 3n adult psych, 7p-7a

    Job Description Summary The Registered Nurse (Hospital-Based) is a competent registered nurse that will deliver nursing care to patients of varying age groups by utilizing the nursing process and...

    onsite, Louisville, KY, United States
    Full TimeJunior (<2 years)

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