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  4. Nurse Practitioner

Onsite Nurse Practitioner jobs in San Antonio, Texas, USA

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Nurse Practitioner Jobs in San Antonio — On-Site Opportunities Await

San Antonio's healthcare system continues to expand, creating steady demand for skilled clinicians who can deliver direct patient care. This on-site role offers 500+ open positions for professionals ready to join a collaborative clinical team in Texas. Hospitals and clinics across the region are actively seeking candidates to fill nurse practitioner jobs in San Antonio, reflecting the city's growing population and healthcare needs.

Success in this profession requires strong clinical judgment, excellent communication skills, and the ability to manage diverse patient caseloads independently. Employers look for candidates who hold current licensure, board certification, and a solid background in diagnosing and treating a variety of conditions. Compassion, adaptability, and a commitment to patient-centered care remain essential traits for anyone pursuing nurse practitioner positions, whether early in their career or further along.

On-site work for this role means being present in clinical settings, collaborating closely with physicians, nurses, and administrative staff to coordinate patient care. San Antonio's expanding medical facilities, including major hospital networks and outpatient centers, continue to hire a nurse practitioner to meet rising community healthcare demands. The local job market remains strong, with steady opportunities across both urban and suburban practices.

If you're ready to advance your career in a thriving healthcare community, explore current nurse practitioner vacancies available through Global Work AI. Take the next step toward a rewarding on-site role where your clinical expertise can make a real difference every day.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average nurse practitioner salary in San Antonio?

    In San Antonio, a nurse practitioner salary typically falls in the low- to mid-$110,000 range, though pay can move higher with specialty experience, evening coverage, or advanced procedural skills. Texas salaries also vary by employer type, such as hospital systems, urgent care, primary care, and specialty clinics. Benefits, productivity bonuses, and shift differentials may add meaningful value beyond base pay. When reviewing openings in San Antonio, compare compensation with scope of practice, patient volume, and required duties so you can judge the full package, not just the headline number.
  • What qualifications do I need to apply for a nurse practitioner job?

    Most employers in San Antonio look for an active RN license, an accredited graduate degree in nursing, and national certification in the relevant population focus, such as family, adult-gerontology, or acute care. A strong clinical background as a registered nurse is usually expected, along with experience that matches the setting. Some hiring teams prefer prior work in primary care, emergency, or specialty medicine. Because job requirements can differ across Texas employers, it helps to review recent postings closely and compare the education, experience, and credential mix they list.
  • What clinical skills and certifications are required for a nurse practitioner position in Texas?

    Hiring managers in Texas usually want solid assessment, diagnosis, care-planning, and medication-management skills, plus confidence with electronic health records and patient education. Common certifications include national nurse practitioner board certification in the correct specialty, current BLS, and often ACLS or PALS depending on the unit or clinic. In San Antonio, employers may also value wound care, chronic disease management, women’s health, pediatrics, or acute care experience. Matching your certification set to the department can strengthen your application, so it’s worth checking each listing for specialty-specific expectations.
  • What are the main responsibilities of a nurse practitioner in an on-site healthcare setting?

    In an on-site healthcare setting, a nurse practitioner usually evaluates patients, reviews histories, orders and interprets tests, develops treatment plans, and prescribes therapies within state rules. Day-to-day work may also include preventive care, follow-up visits, medication counseling, and coordination with physicians, nurses, and other clinicians. In San Antonio facilities, the pace can vary from same-day access clinics to hospital-based services, so patient load and acuity may change by employer. Looking at the clinical environment and team structure can help you understand how broad the role will be.
  • How does the hiring process usually work for nurse practitioner jobs in San Antonio?

    The process often starts with an application review, followed by phone screening, interviews, and credential verification. For a nurse practitioner role in San Antonio, employers may ask about population focus, charting systems, scope of practice, and comfort with on-site workflow. Background checks, reference calls, and license validation are common before an offer. Some healthcare systems also include panel interviews or shadowing time. If you are comparing openings, it can help to note which employers move quickly and which require multiple rounds, since timelines vary across Texas facilities.
  • What work schedule and on-site conditions can I expect in a nurse practitioner job in San Antonio?

    Schedules depend on the setting, but many on-site nurse practitioner jobs in San Antonio follow weekday clinic hours, while others involve rotating shifts, weekends, call coverage, or extended hours. Hospital and urgent care roles may be more fast paced, while primary care usually offers steadier daytime schedules. You can also expect time spent standing, moving between rooms, and working in busy clinical spaces with direct patient contact. Reviewing posted hours, patient volumes, and call expectations can give you a clearer picture of daily conditions before you apply.
  • Are there any Texas state licensure or prescribing requirements for nurse practitioners?

    Yes. In Texas, a nurse practitioner must hold a current RN license and advanced practice recognition through the Texas Board of Nursing, along with national certification in the appropriate role and population focus. Prescribing controlled substances also involves extra steps, including a valid DEA registration and compliance with Texas delegation and prescriptive authority rules. Employers in San Antonio may expect proof of these credentials before onboarding. Because requirements can change and may differ by setting, it is smart to confirm current state rules and compare them with each job listing before moving forward.

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500+ jobs found

  • University Health

    University Health

    Today

    Nurse practitioner / physician assistant - gyn oncology

    Position Overview We are seeking a highly motivated and compassionate Advanced Practice Provider (PA or NP) to join our Gynecologic Oncology team at University Health San Antonio. This is an...

    onsite, San Antonio, TX, United States
    $107k/yrFull TimeEntry with Degree
  • NP Now

    NP Now

    Today

    Family nurse practitioner - primary care

    Well-established Healthcare system is looking to hire a Family Nurse Practitioner to work in San Antonio, TX! Join a group of like-minded, energetic, smart, curious and health-conscious medical...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • NP Now

    NP Now

    Today

    Nurse practitioner / np or physician assistant / pa - dermatology

    Dermatology Nurse Practitioner | San Antonio, TX Lead a growing dermatology practice while enjoying exceptional work-life balance and clinical autonomy. A well-established, mission-driven healthcare...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • NP Now

    NP Now

    Today

    Family nurse practitioner

    Well-established Healthcare system is looking to hire a Family Nurse Practitioner to work in San Antonio, TX! Join a group of like-minded, energetic, smart, curious and health-conscious medical...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Suncrest Hospice

    Suncrest Hospice

    Today

    Nurse practitioner *prn basis m-f daytime hours*

    Why Suncrest At Brighton/Suncrest Hospice our goal is to change the expectation of hospice care in your area by providing exceptional care and service to our patients. This is achieved by allocating...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • University Health

    University Health

    a day ago

    Nurse practitioner

    POSITION SUMMARY/RESPONSIBILITIES Serves as member of health care team that provides specialized health care including preventive care and on-going health maintenance for selected groups of patients....

    onsite, San Antonio, TX, United States
    $107k – $160k/yrFull TimeMiddle (2-4 years)
  • ERP International

    ERP International

    2 days ago

    Nurse practitioner - psychiatric mental health

    Overview ERP International is seeking a Nurse Practitioner for a Full-Time position in support of the DMH Acute Psychiatry Department (Inpatient) at NMC San Diego. Apply online today and discover...

    onsite, Laurel, MD, United States
    $202k – $222k/yrFull TimeLead / Manager
  • Concentra

    Concentra

    5 days ago

    Nurse practitioner or physician assistant prn

    Overview Are you ready to take your career to new heights? At Concentra, you will be a vital member of our patient care team and play a crucial role in providing exceptional care to our patients. Our...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Alamo City Urgent Care

    Alamo City Urgent Care

    5 days ago

    Nurse practitioner

    Who We Are Who You Are Alamo City Urgent Care is seeking a dedicated and experienced Family Nurse Practitioner (FNP) to join our dynamic clinical team. This role is ideal for a provider who thrives...

    onsite, San Antonio, TX, United States
    $151k – $161k/yrFull TimeJunior (<2 years)
  • Concentra

    Concentra

    5 days ago

    Nurse practitioner or physician assistant float

    Overview Bonus Potential! Monthly and Quarterly Bonus Incentives! Are you looking for a physician practice with a family environment, but with the benefits and support a large organization can...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Urology San Antonio

    Urology San Antonio

    5 days ago

    Advanced practice provider (nurse practitioner or physician assistant)

    Urology San Antonio Advanced Practice Provider (Nurse Practitioner or Physician Assistant) Northeast Clinic | Full-Time Make a Difference with One of the Nation's Leading Urology Practices Are you...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Decypher

    Decypher

    5 days ago

    Nurse practitioner family health

    Join Decypher and make a direct impact on the health and readiness of America’s service members, veterans, and their families. Since 2008 Decypher has offered healthcare industry professionals...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • C

    CHRISTUS Health

    6 days ago

    Np, nurse practitioner/pa, physician assistant- cardiology

    We are seeking an experienced Nurse Practitioner or Physician Assistant to join our cardiology team in San Antonio, TX. This role offers a balanced mix of inpatient and outpatient responsibilities,...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Serenity Mental Health Centers

    Serenity Mental Health Centers

    6 days ago

    Psychiatric nurse practitioner (pmhnp)

    Psychiatric Nurse Practitioner (PMHNP) San Antonio West, TX Tired of being treated like a cog in a large corporate health system? Exhausted by the amount of time you spend with administrative work...

    onsite, San Antonio, TX, United States
    $150k/yrFull TimeJunior (<2 years)
  • Texas Health & Human Services Commission

    Texas Health & Human Services Commission

    7 days ago

    Psychiatric advanced nurse practitioner

    Join the Texas Health and Human Services Commission (HHSC) and be part of a team committed to creating a positive impact in the lives of fellow Texans. At HHSC, your contributions matter, and we...

    onsite, San Antonio, TX, United States
    $149k – $172k/yrFull TimeJunior (<2 years)
  • PRM of Texas, PA

    PRM of Texas, PA

    7 days ago

    Nurse practitioner – women’s health, fertility & aesthetics | san antonio

    Pelvic Rehabilitation Medicine (PRM) is a National Women’s healthcare organization whose core business is providing evidence-based treatment for persistent pelvic pain and Endometriosis with a...

    onsite, San Antonio, TX, United States
    $85k – $100k/yrFull TimeMiddle (2-4 years)
  • Total Primary Care

    Total Primary Care

    7 days ago

    Nurse practitioner (np)/physician assistant (pa) - san antonio, tx

    Nurse Practitioner (NP)/Physician Assistant (PA) - San Antonio, TX Shape the future of primary care, have a voice and love your patients! This is what we do at Total Primary Care. We’ve built a...

    onsite, San Antonio, TX, United States
    $120k/yrFull TimeJunior (<2 years)
  • HealthTexas Primary Care Doctors

    HealthTexas Primary Care Doctors

    7 days ago

    Family nurse practitioner - perrin beitel

    The Family Nurse Practitioner is responsible for performing physical examinations, diagnosing illnesses, developing and implementing treatment plans, and educating patients and families on health...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • HealthTexas Primary Care Doctors

    HealthTexas Primary Care Doctors

    7 days ago

    Family nurse practitioner - val verde

    The Family Nurse Practitioner is responsible for performing physical examinations, diagnosing illnesses, developing and implementing treatment plans, and educating patients and families on health...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Tenet Healthcare Corporation

    Tenet Healthcare Corporation

    8 days ago

    Nurse practitioner - inpatient neurology - san antonio, tx

    Join a leading neuroscience program in San Antonio, Texas, as a full-time Nurse Practitioner providing inpatient Neurology care. This position offers the opportunity to work collaboratively with...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Spectrum Healthcare Resources

    Spectrum Healthcare Resources

    9 days ago

    Nurse practitioner

    Job Description Spectrum Healthcare Resources has a potential opening for a Nurse Practitioner (Family Medicine) at Lackland AFB in Reid Medical Clinic, San Antonio, TX. This is your opportunity to...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • University Health

    University Health

    9 days ago

    Specialty nurse practitioner

    POSITION SUMMARY/RESPONSIBILITIES Serves as member of health care team that provides specialized health care including preventive care and on-going health maintenance for selected groups of patients....

    onsite, San Antonio, TX, United States
    $107k – $160k/yrFull TimeMiddle (2-4 years)
  • UnitedHealth Group

    UnitedHealth Group

    10 days ago

    7 on/7 off - hospitalist nurse practitioner or physician assistant – wellmed networks, inc – san antonio, tx

    WellMed, part of the Optum family of businesses, is seeking a nurse practitioner or physician assistant to join our Hospitalist Team in San Antonio, TX. Optum is a clinician-led care organization...

    onsite, San Antonio, TX, United States
    $110k/yrFull TimeJunior (<2 years)
  • ENDEAVORS

    ENDEAVORS

    11 days ago

    Psychiatric nurse practitioner

    Job Details Job Location: TX SanAntonio VWC - San Antonio, TX Position Type: Full-Time Education Level: Masters Degree Salary Range: $110000.00 - $150000.00 Salary/year Job Shift: Days Endeavors is...

    onsite, San Antonio, TX, United States
    $110k/yrFull TimeJunior (<2 years)
  • University Health

    University Health

    12 days ago

    Critical care advanced practice provider nurse practitioner - physician assistant

    Critical Care Advanced Practice Provider Nurse Practitioner - Physician Assistant University Health in San Antonio is seeking board-certified Advanced Practice Providers (Acute Care Nurse...

    onsite, San Antonio, TX, United States
    $107k/yrFull TimeJunior (<2 years)
  • CommuniCare Health Center Jobs

    CommuniCare Health Center Jobs

    12 days ago

    Pediatric nurse practitioner (ph0813 - potranco)

    The Pediatric Nurse Practitioner provides quality, comprehensive out-patient primary health care services to the Center’s pediatric patients consulting with supervising physician and abiding by...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • Addison Kenway.

    Addison Kenway.

    12 days ago

    Dermatology nurse practitioner or physician assistant

    Dermatology Nurse Practitioner or Physician Assistant Job Opening in San Antonio, Texas Experienced Dermatology Nurse Practitioner or Physician Assistant needed for a comprehensive dermatology...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • T

    The Harbor Health Team

    12 days ago

    (app) nurse practitioner / physician assistant - bitters

    POSITION OVERVIEW Harbor Health is seeking a team-oriented Nurse Practitioner or Physician Assistant to join our multi-specialty clinic group in San Antonio at our Bitters practice. As a clinical...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • P

    Purposelink Recruitment

    12 days ago

    Telehealth nurse practitioner

    Nurse Practitioner – Value‑Based Care Contract | New Mexico (TX or NM Residents) Required Qualifications Master's degree or higher 2+ year of Telemedicine Care experience 3+ years of recent Primary...

    onsite, San Antonio, TX, United States
    $135k/yrFull TimeJunior (<2 years)
  • T

    The Harbor Health Team

    12 days ago

    (app) nurse practitioner / physician assistant - babcock

    POSITION OVERVIEW Harbor Health is seeking a team-oriented Nurse Practitioner or Physician Assistant to join our multi-specialty clinic group in San Antonio at our Babcock practice. As a clinical...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • CommuniCare Health Center Jobs

    CommuniCare Health Center Jobs

    12 days ago

    Family nurse practitioner - rheumatology (ph3511 - luckey ranch)

    The Family Nurse Practitioner provides quality, comprehensive primary health care services to the Center’s Rheumatology patients consulting with supervising physician and abiding by appropriate...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • T

    The Harbor Health Team

    12 days ago

    (app) nurse practitioner/physician assistant - prn - san antonio

    POSITION OVERVIEW Harbor Health is seeking a dedicated PRN Nurse Practitioner or Physician Assistant to join our clinical team in San Antonio, TX. In this role, you will deliver comprehensive,...

    onsite, San Antonio, TX, United States
    $16k/yrPart TimeJunior (<2 years)
  • University Health

    University Health

    12 days ago

    Nurse practitioner / physician assistant

    POSITION SUMMARY/RESPONSIBILITIES Serves as member of health care team that provides specialized health care including preventive care and on-going health maintenance for selected groups of patients....

    onsite, San Antonio, TX, United States
    Full TimeMiddle (2-4 years)
  • Cherokee Federal

    Cherokee Federal

    19 days ago

    Nurse practitioner, aprn, fnp

    A government contract requires that this position be restricted to U.S. citizens. This position requires a Common Access Card (CAC), and the ability to pass the U.S. Department of Defense (DoD)...

    onsite, Albuquerque, NM, United States
    $120k – $130k/yrFull TimeJunior (<2 years)
  • Nexus Health Systems Ltd

    Nexus Health Systems Ltd

    20 days ago

    Psych nurse practitioner

    PSYCHIATRIC MENTAL HEALTH NURSE PRACTITIONER (PMHNP) Nexus Neurorecovery Center – San Antonio, TX Setting: Residential Treatment Center for Adolescent Females ABOUT US Nexus Neurorecovery Center –...

    onsite, San Antonio, TX, United States
    Full TimeMiddle (2-4 years)
  • Nexus Health Systems Ltd

    Nexus Health Systems Ltd

    20 days ago

    Family nurse practitioner

    FAMILY NURSE PRACTITIONER (FNP) Nexus Neurorecovery Center – San Antonio, TX Setting: Residential Treatment Center for Adolescent Females ABOUT US Nexus Neurorecovery Center – San Antonio provides...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • CommuniCare

    CommuniCare

    22 days ago

    Family nurse practitioner - rheumatology (ph3511 - luckey ranch)

    The Family Nurse Practitioner provides quality, comprehensive primary health care services to the Center’s Rheumatology patients consulting with supervising physician and abiding by appropriate...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • U.S. Renal Care, Inc.

    U.S. Renal Care, Inc.

    23 days ago

    Nurse practitioner, vbc san antonio

    Responsibilities SUMMARY Essential Duties and Responsibilities include the following. Other duties and tasks may be assigned. Primary duties include: ESKD rounding, including limited and...

    onsite, San Antonio, TX, United States
    Full TimeJunior (<2 years)
  • CenterWell

    CenterWell

    a month ago

    Nurse practitioner

    Become a part of our caring community Join a Team That's Redefining Senior Primary Care Humana's Primary Care Organization is one of the largest and fastest-growing senior-focused, value-based care...

    onsite, San Antonio, TX, United States
    $124k – $170k/yrFull TimeJunior (<2 years)
  • GARDAWORLD FEDERAL SERVICES LLC

    GARDAWORLD FEDERAL SERVICES LLC

    a month ago

    Nurse practitioner

    POSITION INFORMATION: BASIC DETAILS Location: San Antonio, TX Full-Time/Part-Time: Full-time FLSA Status: Non-Exempt/Hourly Travel Requirement: No Teleworking: No Pay: $73.50/hr. *Pay rates listed...

    onsite, San Antonio, TX, United States
    $148k/yrFull TimeJunior (<2 years)

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