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  4. Nurse Practitioner

Onsite Nurse Practitioner jobs in San Diego, California, USA

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Nurse Practitioner Jobs in San Diego: On-Site Roles for Dedicated Caregivers

San Diego's healthcare sector continues to grow, creating strong demand for nurse practitioner jobs in San Diego across hospitals, clinics, and community health centers. This on-site role offers 188 open positions for professionals eager to deliver direct, hands-on patient care. With California's expanding population and healthcare needs, qualified professionals are highly sought after in this vibrant coastal city.

Successful candidates bring a strong clinical foundation, excellent diagnostic skills, and the ability to manage patient care independently. Employers typically look to hire a nurse practitioner who demonstrates compassionate communication, sound judgment under pressure, and up-to-date knowledge of evidence-based practices. Familiarity with electronic health records, strong collaboration with physicians and support staff, and a commitment to continuous learning are also highly valued traits in this field.

On-site nurse practitioner positions in San Diego typically involve direct patient interaction within clinical or hospital settings, requiring a physical presence to support diagnosis, treatment planning, and patient education. The region's robust healthcare infrastructure and growing population fuel consistent hiring activity, making San Diego one of California's most promising markets for nurse practitioner vacancies. Employers increasingly value professionals ready to engage fully with on-site teams and patients.

If you're ready to make a meaningful impact in patient care, explore the latest nurse practitioner opportunities available through Global Work AI. Take the next step in your healthcare career and discover how your skills can thrive in San Diego's dynamic medical community.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average nurse practitioner salary in San Diego?

    In San Diego, pay for a nurse practitioner typically falls in the roughly $130,000 to $160,000 range per year, though compensation can move higher in specialty care, acute settings, or roles with added shift differentials. California wages for advanced practice providers are among the strongest in the country, and local employer budgets often reflect the region’s cost of living. Experience, board certification, patient volume, and benefit package all affect the total offer. It helps to compare current San Diego listings, since posted ranges can vary by department and setting.
  • What qualifications do you need to become a nurse practitioner in California?

    To practice as a nurse practitioner in California, you generally need an active RN license, a graduate degree in nursing, and completion of an NP program accredited for advanced practice preparation. Most employers in San Diego also expect national board certification in a population focus such as family, adult-gerontology, pediatrics, or psychiatric care. California additionally has state-specific licensure steps through the Board of Registered Nursing. Clinical rotations, strong assessment ability, and familiarity with local care settings all matter, so it is wise to review employer requirements alongside state rules.
  • What certifications and clinical skills are required for a nurse practitioner role?

    Most employers look for current national certification in the applicant’s specialty, such as FNP, AGNP, or PMHNP credentials, plus an active California license or eligibility to obtain one. In a nurse practitioner role, solid diagnostic reasoning, history taking, physical assessment, medication management, and patient education are essential. On-site hospitals and clinics in San Diego also value EHR proficiency, evidence-based decision-making, and comfort collaborating with physicians and care teams. Depending on the unit, skills in urgent care, chronic disease management, or procedural support may also strengthen a profile.
  • What does a nurse practitioner do in an on-site hospital or clinic setting?

    In a hospital or clinic in San Diego, a nurse practitioner often evaluates patients, orders and interprets tests, develops treatment plans, and prescribes medications within California practice rules. Day to day work may include follow-up visits, preventive care, discharge planning, and coordination with physicians, nurses, and specialists. In an on-site environment, quick access to patients and the care team supports faster decisions and smoother handoffs. Duties can shift by specialty, so reviewing the exact unit description is useful when comparing nurse practitioner openings.
  • How does the hiring process work for a nurse practitioner job in San Diego?

    The hiring path usually starts with an application review, followed by screening for license status, certification, education, and specialty fit. Many San Diego employers then schedule one or more interviews with clinical leaders, hiring managers, or physician partners. Some settings include skills discussion, case questions, background checks, and verification of references or credentials before an offer is made. Because California health systems often move carefully on compliance and onboarding, timelines can vary. It is helpful to gather licensure documents early and compare similar roles while the process moves forward.
  • What are the typical work hours and on-call expectations for an on-site nurse practitioner?

    Schedules can differ widely by department, but many on-site nurse practitioner jobs in San Diego follow weekday clinic hours, rotating hospital shifts, or coverage blocks that include evenings and weekends. Acute care, urgent care, and specialty services may also include on-call rotation, while outpatient practices are often more predictable. On-call expectations depend on patient volume, unit size, and whether the role supports admissions, consults, or post-discharge coverage. Reviewing shift details and call burden in each posting is the best way to compare options before applying.
  • What career growth opportunities are available for nurse practitioners in healthcare roles?

    Career paths for a nurse practitioner in healthcare can expand in several directions, including specialty practice, leadership, education, telehealth, quality improvement, and advanced clinical coordination. In California, experienced NPs may move into supervisory or program development roles, especially within larger hospital systems in San Diego. Some professionals build depth in oncology, cardiology, behavioral health, or emergency care, while others step into operational or policy work. Additional certifications, residency-style training, or stronger business and leadership experience can open more doors, so it helps to track roles that match your long-term goals.

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188 jobs found

  • SCA Health

    SCA Health

    Today

    Registered nurse preop pacu ii - la jolla orthopedic

    Overview At SCA Health, we believe health care is about people – the patients we serve, the physicians we support and the teammates who push us forward. Behind every successful facility, procedure or...

    onsite, San Diego, CA, United States
    $101k – $111k/yrFull TimeJunior (<2 years)
  • Vantage Search Group

    Vantage Search Group

    Today

    Nurse practitioner - psychiatric mental health 5399

    We have a great new opening for a Nurse Practitioner - Psychiatric Mental Health at the Naval Medical Center San Diego. Job Specific Position Duties include, but are not limited to the following:...

    onsite, San Diego, CA, United States
    $208k – $229k/yrFull TimeMiddle (2-4 years)
  • Seaport Scripps Home Health

    Seaport Scripps Home Health

    a day ago

    Registered nurse clinical manager - home health

    Registered Nurse Clinical Manager - Home Health Pay Range: $120,000 - $145,000 annually Job Type: Full Time Join the Seaport Scripps Home Health Family! At Seaport Scripps Home Health, a Scripps...

    onsite, San Diego, CA, United States
    $120k – $145k/yrFull TimeJunior (<2 years)
  • Sutter Health

    Sutter Health

    a day ago

    Ambulatory services nurse ii, pacu

    We are so glad you are interested in joining Sutter Health! Organization: SOPS-Sutter Outpatient Services - San Diego Position Overview: Accountable for the assessment, planning, treatment and...

    onsite, San Diego, CA, United States
    $138k – $193k/yrPart TimeJunior (<2 years)
  • CHP Health

    CHP Health

    a day ago

    Nurse practitioner- mat program

    About Correctional Healthcare Partners: Correctional Healthcare Partners (CHP Health) is a company dedicated to providing healthcare services to the incarcerated, and we're growing. We exist because...

    onsite, San Diego, CA, United States
    $181k – $212k/yrFull TimeJunior (<2 years)
  • Vera Whole Health

    Vera Whole Health

    2 days ago

    Primary care nurse practitioner - san diego, ca (vera health)

    Job Description Summary Provides comprehensive advanced practice primary care services for patients across the lifespan in ambulatory and community-based care settings. Evaluates, diagnoses, and...

    onsite, San Diego, CA, United States
    $130k – $195k/yrPart TimeJunior (<2 years)
  • Vera Whole Health

    Vera Whole Health

    2 days ago

    Nurse practitioner

    Job Description Summary Provides comprehensive advanced practice primary care services for patients across the lifespan in ambulatory and community-based care settings. Evaluates, diagnoses, and...

    onsite, San Diego, CA, United States
    $130k – $195k/yrFull TimeJunior (<2 years)
  • Military Treatment Facilities under DHA

    Military Treatment Facilities under DHA

    3 days ago

    Advanced practice nurse (nurse practitioner)

    Summary About the Position: This position is located at the Naval Branch Health Clinic, Marine Corps Air Station Miramar, San Diego, CA in the Directorate of Medicine, Family Medical Team One (PCMH)....

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Vantage Search Group

    Vantage Search Group

    5 days ago

    Registered nurse - emergency room (prn) 5394

    We have a new need for a Registered Nurse - Emergency Room at the Naval Medical Center in San Diego, CA. Job Specific Details and Tasks: The duties for the RN include but are not limited to the...

    onsite, San Diego, CA, United States
    $157k – $177k/yrFull TimeMiddle (2-4 years)
  • Aurora San Diego

    Aurora San Diego

    5 days ago

    Registered nurse educator (full time)

    As Nurse Educator/Infection Control, this position is responsible for organizing, evaluating, and training employees and directors to improve practice competency and patient outcome. At the same...

    onsite, San Diego, CA, United States
    $107k – $121k/yrFull TimeLead / Manager
  • Lorian Health

    Lorian Health

    5 days ago

    Home health registered nurse clinical manager - rncm

    Join a Team That Makes a Difference For more than 20 years, Lorian Health has been a trusted leader in home health care, delivering compassionate, patient-centered care that enhances quality of life...

    onsite, San Diego, CA, United States
    $135k – $145k/yrFull TimeJunior (<2 years)
  • ERP International

    ERP International

    6 days ago

    Registered nurse - emergency room (prn days)

    Overview ERP International, LLC is seeking a Emergency Room Registered Nurse for a PRN position supporting the Naval Medical Center San Diego, CA. Be the Best! Join our team of exceptional health...

    onsite, San Diego, CA, United States
    $157k – $177k/yrPart TimeMiddle (2-4 years)
  • PREMIER AMBULANCE

    PREMIER AMBULANCE

    6 days ago

    Cct registered nurse

    Job Details: Level: Experienced Job Location: San Diego - San Diego, CA Position Type: Full-Time/Part-Time Salary Range: $100000.00 - $150000.00 Salary/year Job Shift: Any Premier Ambulance is...

    onsite, San Diego, CA, United States
    $100k/yrFull TimeJunior (<2 years)
  • Eleutheria

    Eleutheria

    6 days ago

    Licensed vocational nurse

    Job Title: Licensed Vocational Nurse Pay Range: $25-$28/Hourly Job Description: 25-38 /Hr | Part-Time | San Diego, CA | School-Based | 2026-2027 school year | About the Role: Help facilitate the care...

    onsite, San Diego, CA, United States
    $50k – $56k/yrPart TimeJunior (<2 years)
  • San Ysidro Health

    San Ysidro Health

    7 days ago

    Registered nurse

    Position Summary: Under direct supervision and within established scope of practice, the Ambulatory Care Registered Nurse ensures the delivery of patient-centered services as directed by San Ysidro...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Military Treatment Facilities under DHA

    Military Treatment Facilities under DHA

    8 days ago

    Nurse (clinical/psychiatric)

    Summary This is a Direct Hire Solicitation Duties Perform a comprehensive mental health nursing assessment to identify existing and potential problems and formulate a nursing plan of care. Teach...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Cheer Home Care

    Cheer Home Care

    8 days ago

    Part-time concierge rn nurse care manager

    About Us We are a premier concierge private nursing in-home company dedicated to delivering bespoke, elevated care to private-pay clients. We believe that exceptional client care starts with...

    onsite, San Diego, CA, United States
    $121k – $141k/yrPart TimeMiddle (2-4 years)
  • Neighborhood House Association

    Neighborhood House Association

    8 days ago

    Registered nurse manager - bpsr

    Career Opportunities with Neighborhood House Association About NHA: The Neighborhood House Association is a non-profit organization. Head Start positions are funded in whole or in part by money...

    onsite, San Diego, CA, United States
    Full TimeMiddle (2-4 years)
  • Pennant Group

    Pennant Group

    9 days ago

    Registered nurse clinical manager - home health

    Registered Nurse Clinical Manager - Home Health Pay Range: $120,000 - $145,000 annually Job Type: Full Time Join the Seaport Scripps Home Health Family! At Seaport Scripps Home Health, a Scripps...

    onsite, San Diego, CA, United States
    $120k – $145k/yrFull TimeJunior (<2 years)
  • Fresenius Medical Care

    Fresenius Medical Care

    9 days ago

    Registered nurse - rn - dialysis

    Paid one on one training and education provided Empower, engage and train dialysis patients on peritoneal and home hemodialysis using state of the art training programs and equipment Primarily works...

    onsite, San Diego, CA, United States
    $71k/yrFull TimeJunior (<2 years)
  • U.S. Military Entrance Processing Command

    U.S. Military Entrance Processing Command

    11 days ago

    Advanced practice nurse (nurse practitioner)

    Summary This is a Direct Hire Authority (DHA) solicitation utilizing the DHA for Certain Personnel of the DoD Workforce to recruit and appoint qualified candidates to positions in the competitive...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • San Diego State University

    San Diego State University

    12 days ago

    Per diem nurse practitioner

    Position Summary The Per Diem Nurse Practitioner plays an essential role in providing high-quality, efficient, and cost-effective medical care to San Diego State University students. Under the...

    onsite, San Diego, CA, United States
    $139k/yrFull TimeJunior (<2 years)
  • LifeStance Health

    LifeStance Health

    12 days ago

    Psychiatric mental health nurse practitioner (pmhnp)

    At LifeStance Health, we believe in a truly healthy society where mental and physical healthcare are unified to make lives better. Our mission is to help people lead healthier, more fulfilling lives...

    onsite, San Diego, CA, United States
    $200k – $250k/yrFull TimeJunior (<2 years)
  • Gary and Mary West PACE

    Gary and Mary West PACE

    12 days ago

    Nurse practitioner - provider - $5,000.00 sign on bonus

    $5,000.00 sign on bonus Join the Team Voted Best Place to Work! Why Work for Gary and Mary West PACE? Because you're looking for more than just a job - you want work/life balance and the opportunity...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Point Loma Nazarene University

    Point Loma Nazarene University

    13 days ago

    Health promotion center nurse practitioner

    PLNU is a Christian liberal arts university in the evangelical, Wesleyan tradition, offering quality undergraduate, graduate and professional programs. We provide higher education in a vibrant...

    onsite, San Diego, CA, United States
    $107k/yrPart TimeJunior (<2 years)
  • The Arc of San Diego

    The Arc of San Diego

    14 days ago

    Registered nurse (mon-fri 9a-5:30p)

    Join Our Passionate Team at The Arc of San Diego! Are you ready to make a real difference in the lives of children and adults with disabilities? At The Arc of San Diego, we are the largest and most...

    onsite, San Diego, CA, United States
    $95k – $105k/yrFull TimeJunior (<2 years)
  • AFC Urgent Care San Diego

    AFC Urgent Care San Diego

    15 days ago

    Nurse practitioner full time

    Benefits: Health insurance Paid time off Training & development Vision insurance 401(k) 401(k) matching Bonus based on performance Dental insurance Flexible schedule AFC Urgent Care is the leading...

    onsite, San Diego, CA, United States
    $149k – $157k/yrFull TimeJunior (<2 years)
  • IVY FERTILITY

    IVY FERTILITY

    16 days ago

    Advanced practice provider-nurse practitioner/physican assistant

    Job Details: Job Location: SDFC - Del Mar - San Diego, CA Position Type: Full-Time Salary Range: $125000.00 - $140000.00 Company Overview San Diego Fertility Center is a world-class reproductive...

    onsite, San Diego, CA, United States
    $125k – $140k/yrFull TimeJunior (<2 years)
  • Lorian Health

    Lorian Health

    16 days ago

    Home health rn (registered nurse)

    Join a Team That Makes a Difference For over 20 years, Lorian Health has been a trusted leader in home health care, dedicated to enhancing patients’ quality of life and supporting their independence....

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Cherokee Federal

    Cherokee Federal

    19 days ago

    Nurse practitioner, aprn, fnp

    A government contract requires that this position be restricted to U.S. citizens. This position requires a Common Access Card (CAC), and the ability to pass the U.S. Department of Defense (DoD)...

    onsite, Anchorage, AK, United States
    $120k – $130k/yrFull TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    19 days ago

    Nurse practitioner - generational health, aim - sharp memorial hospital - day shift - full time

    Hours: Shift Start Time: Variable Shift End Time: Variable AWS Hours Requirement: 10/40 - 10 Hour Shift Additional Shift Information: To be discussed upon interview Weekend Requirements: As Needed...

    onsite, San Diego, CA, United States
    $157k – $227k/yrFull TimeJunior (<2 years)
  • Sharp HealthCare

    Sharp HealthCare

    19 days ago

    Nurse practitioner- pulmonary - sharp memorial hospital - day shift - part-time (.8)

    Hours: Shift Start Time: 8 AM Shift End Time: 4:30 PM AWS Hours Requirement: 8/40 - 8 Hour Shift Additional Shift Information: Weekend Requirements: No Weekends On-Call Required: No Hourly Pay Range...

    onsite, San Diego, CA, United States
    $157k – $227k/yrPart TimeJunior (<2 years)
  • McAlister Institute

    McAlister Institute

    21 days ago

    Registered nurse

    Join McAlister Institute, a 49-year beacon in San Diego's Recovery Community. The Recovery and Bridge Center’s Sobering Services is seeking a dedicated Registered Nurse to join our team. Reporting...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • Kindred Healthcare

    Kindred Healthcare

    22 days ago

    Registered nurse - full time days

    Kindred Hospital San Diego is a 70-bed long-term acute care hospital offering the same in-depth care you would receive in a traditional hospital, but for an extended recovery period. We partner with...

    onsite, San Diego, CA, United States
    $84k – $103k/yrFull TimeJunior (<2 years)
  • IconicCare

    IconicCare

    a month ago

    Physiatry (pm&r) nurse practitioner / physician assistant

    Day-to-Day Responsibilities As a physiatrist, you will round at 1–3 Skilled Nursing Facilities or similar rehabilitation centers, 1–3 days per week at each location. Your primary focus will be...

    onsite, San Diego, CA, United States
    $175k – $260k/yrFull TimeEntry with Degree
  • CSU Careers

    CSU Careers

    a month ago

    Assistant professor of school of nursing - clinical nurse specialist

    Position description The San Diego State University School of Nursing (SON) seeks to hire a tenure-track assistant professor with expertise as a Clinical Nurse Specialist. Applicants must hold an...

    onsite, San Diego, CA, United States
    $103k – $110k/yrFull TimeJunior (<2 years)
  • Veterans Health Administration

    Veterans Health Administration

    a month ago

    Nurse manager - ambulatory surgery unit (asu), post anesthesia care unit (pacu)

    Summary The Ambulatory Surgery Unit (ASU), Post Anesthesia Care Unit (ASU), Nursing Interventional Radiology (IR) Cardiac Catheterization and Electrophysiology (Cath/EP) Lab Registered Nurse Manager...

    onsite, San Diego, CA, United States
    $153k/yrFull TimeMiddle (2-4 years)
  • San Diego American Indian Health Center

    San Diego American Indian Health Center

    a month ago

    Behavior - psychiatric nurse practitioner

    We are an FQHC community health center dedicated to embodying the values central to American Indian cultures. This includes respect for our patients, acknowledgement of the whole person, and a focus...

    onsite, San Diego, CA, United States
    Full TimeJunior (<2 years)
  • CHP Health

    CHP Health

    a month ago

    Nurse practitioner/physician assistant - prn

    Advanced Practice Provider (NP/PA) - PRN Overview Correctional Healthcare Partners (CHP) is seeking a dedicated and compassionate Advanced Practice Provider (Nurse Practitioner or Physician...

    onsite, San Diego, CA, United States
    $192k – $202k/yrFull TimeJunior (<2 years)
  • San Diego State University

    San Diego State University

    a month ago

    Assistant professor of school of nursing - clinical nurse specialist

    POSITION DESCRIPTION The San Diego State University School of Nursing (SON) seeks to hire a tenure-track assistant professor with expertise as a Clinical Nurse Specialist. Applicants must hold an...

    onsite, San Diego, CA, United States
    $103k – $110k/yrFull TimeJunior (<2 years)

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