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  1. Onsite Jobs
  2. South Dakota
  3. Sioux Falls
  4. Medical Assistant

Onsite Medical Assistant jobs in Sioux Falls, South Dakota, USA

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  • Sun
    • 1:00 PM - 2:00 PM

      Senior Product Manager Interview

      Sarah Jenkins

    • 2:30 PM - 3:00 PM

      Initial Interview

      Alex Chen

  • Mon
    • 11:00 AM - 11:15 AM

      Product Manager Interview

      David G. (Hiring Manager)

    • 4:15 PM - 5:15 PM

      First Round Interview

      Sophie L.

  • Tue
    • 1:20 PM - 1:45 PM

      Introductory Interview

      Marta W.

    • 2:30 PM - 3:00 PM

      Kick-off Interview

      Daria (HR)

  • Wed
    • 1:00 PM - 1:45 PM

      Qualifying Interview

      James Miller

    • 5:30 PM - 6:00 PM

      Discovery Interview

      Chris V.

  • Thu
    • 2:30 PM - 3:00 PM

      First Interview

      Michael T.

    • 4:00 PM - 5:00 PM

      Interview

      Den

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Aug 23, 2025

Medical Assistant Jobs in Sioux Falls — On-Site Roles Now Open

Sioux Falls' growing healthcare network is actively seeking 41 dedicated professionals for medical assistant jobs in Sioux Falls, South Dakota. This on-site role offers a chance to support physicians and patients directly within busy clinics and hospitals. As local facilities expand, demand for skilled assistants continues to rise across the region.

Successful candidates bring strong clinical fundamentals, including vital sign monitoring, specimen collection, and accurate documentation in electronic health records. Excellent communication skills help an assistant interact confidently with patients, physicians, and administrative staff, while attention to detail ensures safe, efficient care. Employers looking to hire a medical assistant often prioritize candidates who balance technical knowledge with genuine compassion and adaptability in fast-paced clinical settings.

On-site medical assistant positions in Sioux Falls typically involve full-time schedules within clinics, urgent care centers, or hospital departments, allowing hands-on collaboration with healthcare teams. South Dakota's healthcare sector continues to expand, driven by population growth and increased access to primary care, making this an encouraging market for job seekers. Local employers value professionals who thrive in structured, in-person environments and contribute to consistent patient care quality.

If you're ready to advance your healthcare career, explore current medical assistant vacancies and connect with employers eager to welcome new talent. Global Work AI connects passionate candidates with rewarding opportunities across Sioux Falls and beyond. Take the next step today and apply for a role that matches your skills and ambitions.

Frequently Asked
Questions

Everything you need to know about
finding your next role
  • What is the average medical assistant salary in Sioux Falls?

    Pay for a medical assistant in Sioux Falls, South Dakota, often lands in the mid-$30,000s to low-$40,000s annually, though clinics, specialty practices, and hospital systems may offer more. Local wages can vary with experience, certification, and whether the role includes front-desk duties, injections, or EHR support. Because Sioux Falls has a strong healthcare market, compensation may be competitive compared with smaller South Dakota communities. Reviewing current listings and comparing total benefits can give a clearer picture of the range.
  • What qualifications do you need to become a medical assistant in South Dakota?

    Most employers in South Dakota look for a high school diploma or GED plus training from an accredited medical assistant program. Some clinics in Sioux Falls also value hands-on externship experience, especially for roles that involve rooming patients, taking vitals, and basic lab tasks. While state law does not require a license for every position, employers often prefer candidates who can show competence in clinical and administrative work. Checking local job postings can help confirm which background each office wants.
  • What certifications are preferred for a medical assistant job?

    In the Sioux Falls area, nationally recognized credentials carry the most weight, especially the CMA from AAMA, RMA from AMT, CCMA from NHA, or NCMA from NCCT. Many healthcare employers see certification as proof of training in patient care, safety, and office procedures. CPR or BLS certification is also commonly preferred, particularly in busy clinics or specialty settings. If you are comparing openings, it helps to note whether a practice favors one credential over another before applying.
  • What does a medical assistant do in a typical clinic shift?

    A typical shift usually blends patient care with office support. In an on-site medical assistant role in Sioux Falls, that can mean greeting patients, updating records, taking blood pressure and temperature, preparing exam rooms, assisting providers during visits, and handling phone or scheduling tasks. Some clinics also expect specimen collection, point-of-care testing, or prior authorization support. The exact mix depends on the specialty and size of the practice, so it is worth reviewing each posting for daily duties and workflow details.
  • What skills are most important for a medical assistant position?

    Strong communication matters most, along with accuracy, calm judgment, and comfort working with people of different ages. Employers in South Dakota also value EHR navigation, basic clinical technique, scheduling, and the ability to keep patient information private under HIPAA rules. In fast-paced Sioux Falls clinics, time management and teamwork are especially useful because duties often shift between the front desk and exam rooms. Candidates who can stay organized and adapt quickly tend to stand out when reviewing related openings.
  • What is the hiring process for a medical assistant job like?

    The process usually starts with an application and a close review of experience, training, and credentials. In Sioux Falls, many healthcare employers follow that with a phone screen, an interview, and sometimes a skills check covering vitals, charting, or EHR use. References and background screening are common, and some practices may ask about vaccine status or CPR certification before extending an offer. The pace can vary by clinic size, so it helps to watch current postings for timing clues and required documents.
  • What career growth opportunities are available for a medical assistant in healthcare?

    There are several paths forward after gaining experience in a medical assistant role. In Sioux Falls, some professionals move into lead MA, patient care coordinator, or referral specialist positions, while others cross-train into phlebotomy, billing, or EHR support. Additional schooling can also open doors to nursing, health administration, or specialty clinic work in fields like cardiology and dermatology. Because healthcare systems often promote from within, it is smart to compare openings that mention advancement, cross-training, or tuition support.

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41 jobs found

  • Avera Health

    Avera Health

    Today

    Certified nursing assistant ii (cnaii):mck extended care

    Location: Avera Prince of Peace-Transitional Care Worker Type: Regular Work Shift: Day/Evening/Weekend/Holiday Shift (United States of America) Pay Range: The pay range for this position is listed...

    onsite, Sioux Falls, SD, United States
    $42k – $55k/yrFull TimeEntry with Degree
  • Sanford Health

    Sanford Health

    Today

    Patient access representative | diabetes & thyroid clinic | 40 hrs/week

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $33k – $46k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    a day ago

    Medical assistant - cardiovascular institute - day

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $38k – $51k/yrFull TimeEntry with Degree
  • Sanford Health

    Sanford Health

    a day ago

    Activities assistant - prn - luther manor

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $30k – $45k/yrPart TimeEntry with Degree
  • 5

    5386931e-8aec-4979-9b93-4b7f26ef0a13

    2 days ago

    Human resources assistant

    Why CCI? At CCI Systems, Inc., our mission is simple: Making Life Better through devotion to our world-class employees and delivering innovative solutions for our customers. As a 100% employee-owned...

    onsite, Alexandria, VA, United States
    Full TimeJunior (<2 years)
  • Cinemark

    Cinemark

    2 days ago

    Part-time assistant manager

    Apply in ~60 Seconds Join Our Team: A career at Cinemark means you'll have epic opportunities to immerse yourself in our industry. But that's just the beginning — a front row seat means incredible...

    onsite, Sioux Falls, SD, United States
    $33k – $36k/yrPart TimeEntry with Degree
  • Avera Health

    Avera Health

    2 days ago

    Histology assistant

    Location: Avera McKennan Hospital Worker Type: Regular Work Shift: Primarily days with rotating weekends and holidays (United States of America) Pay Range: The pay range for this position is listed...

    onsite, Sioux Falls, SD, United States
    $36k – $47k/yrFull TimeNo Skills
  • Sanford Health

    Sanford Health

    3 days ago

    Cna - part time pms - sf village

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $37k – $51k/yrPart TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    3 days ago

    Associate credentialing specialist

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $35k – $56k/yrFull TimeJunior (<2 years)
  • Avera Health

    Avera Health

    3 days ago

    Scheduling specialist - avera cancer institute prn

    Location: Avera Cancer Institute-Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate...

    onsite, Sioux Falls, SD, United States
    $37k – $49k/yrPart TimeJunior (<2 years)
  • Avera Health

    Avera Health

    5 days ago

    Patient care technician (pct)|cvs & pulm unit

    Location: Avera McKennan Hospital Worker Type: Regular Work Shift: Rotating days/evenings/nights/weekends/holidays (United States of America) Pay Range: The pay range for this position is listed...

    onsite, Sioux Falls, SD, United States
    $36k – $47k/yrFull TimeJunior (<2 years)
  • Interim HealthCare - Sioux Falls, SD

    Interim HealthCare - Sioux Falls, SD

    5 days ago

    Certified nursing assistant

    Certified Nursing Assistant $24-26 Per Hour | Paid Weekly | Flexible Schedule Who We Are From Yankton to Irene, Wakonda, and Beresford; from Marion to Sioux Falls; and from Brandon to Brookings, we...

    onsite, Sioux Falls, SD, United States
    $48k – $52k/yrPart TimeEntry with Degree
  • Interim HealthCare - Sioux Falls, SD

    Interim HealthCare - Sioux Falls, SD

    5 days ago

    Certified medication aide

    Certified Medication Aide $24-27 Per Hour | Paid Weekly | Flexible Schedule Who We Are From Yankton to Irene, Wakonda, and Beresford; from Marion to Sioux Falls; and from Brandon to Brookings, we are...

    onsite, Sioux Falls, SD, United States
    $48k – $54k/yrPart TimeEntry with Degree
  • Sanford Health

    Sanford Health

    6 days ago

    Patient care technician - pct - medical oncology - ft rotating

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $36k – $48k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    6 days ago

    App - nurse practitioner or physician assistant | interventional radiology

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    Full TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    7 days ago

    Patient care tech - pct - pre-op/recovery care - ft days

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $35k – $46k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    8 days ago

    Medical laboratory scientist / technician - fulltime days

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $47k – $89k/yrFull TimeJunior (<2 years)
  • The Goodman Group, LLC

    The Goodman Group, LLC

    9 days ago

    Ft and pt medication aide-multiple shifts

    The Inn on Westport is hiring for Certified Medication Aides to join their team! Multiple shifts, listed below Summary of Position The Medication Technician plays an integral role in the success of...

    onsite, Sioux Falls, SD, United States
    $34k – $40k/yrPart TimeEntry with Degree
  • The Goodman Group, LLC

    The Goodman Group, LLC

    9 days ago

    On call medication aide-assisted living

    Medication Technician Summary of Position The Medication Technician plays an integral role in the success of our team, our community and creating a place our residents are proud to call home. The...

    onsite, Sioux Falls, SD, United States
    Full TimeJunior (<2 years)
  • Avera Health

    Avera Health

    9 days ago

    Registered nurse (rn) or licensed practical nurse (lpn) or medical assistant | dermatology clinic

    Location: Avera Dermatology Minnesota Ave Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent...

    onsite, Sioux Falls, SD, United States
    $40k – $83k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    9 days ago

    Medical assistant - ma - dermatology clinic

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $38k – $51k/yrFull TimeEntry with Degree
  • Sanford Health

    Sanford Health

    13 days ago

    Cma - full-time evenings - monday to friday - sf center

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $39k – $55k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    13 days ago

    Cma - full time nights weekends - sf center

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $39k – $55k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    14 days ago

    Medical laboratory technician/ scientist

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $50k – $89k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    15 days ago

    Medical assistant - ma - ent

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $38k – $51k/yrFull TimeEntry with Degree
  • Avera Health

    Avera Health

    15 days ago

    Medical assistant | comprehensive breast clinic

    Location: Avera Comprehensive Breast Care Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate...

    onsite, Sioux Falls, SD, United States
    $40k – $56k/yrFull TimeJunior (<2 years)
  • Avera Health

    Avera Health

    15 days ago

    Medical assistant | pulmonary clinic

    Location: Avera Pulmonary & Sleep Medicine Sioux Falls Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay...

    onsite, Sioux Falls, SD, United States
    $40k – $56k/yrFull TimeJunior (<2 years)
  • VANCE THOMPSON VISION CLINIC PROF L

    VANCE THOMPSON VISION CLINIC PROF L

    16 days ago

    Ophthalmic assistant, retina

    Job Details: Job Location: Sioux Falls Clinic - Sioux Falls, SD Education Level: Not Specified Salary Range: Undisclosed Travel Percentage: Negligible Job Shift: Day Job Category: Health Care Why...

    onsite, Sioux Falls, SD, United States
    Full TimeNo Skills
  • Sanford Health

    Sanford Health

    17 days ago

    Lpn - licensed practical nurse - ma - medical assistant - pct - patient care tech - post acute care - ft days

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $33k – $59k/yrFull TimeJunior (<2 years)
  • Avera Health

    Avera Health

    17 days ago

    Registered nurse (rn) or licensed practical nurse or medical assistant | plastic surgery clinic

    Location: Avera Plastic & Reconstructive Surgery Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate...

    onsite, Sioux Falls, SD, United States
    $45k – $83k/yrFull TimeJunior (<2 years)
  • Specialty Dental Brands

    Specialty Dental Brands

    17 days ago

    Registered dental assistant at children's dental center

    At Children's Dental Center we're dedicated to providing compassionate, high-quality dental care to children in a fun and welcoming environment. We are currently seeking a skilled and enthusiastic...

    onsite, Sioux Falls, SD, United States
    Full TimeEntry with Degree
  • Specialty Dental Brands

    Specialty Dental Brands

    17 days ago

    Orthodontic assistant at children's dental center

    Parkway Orthodontics is seeking a full-time Dental Assistant to be part of our amazing team! Our goal at Parkway Orthodontics is to provide a fun environment where all patients can have a positive...

    onsite, Sioux Falls, SD, United States
    $40k – $58k/yrFull TimeJunior (<2 years)
  • Veterans Health Administration

    Veterans Health Administration

    18 days ago

    Supervisory medical support assistant

    Summary This position provides supervision of the MSA in the Community Care (CC) department as well as analytical and evaluative support to the CC Chief regarding scheduling and authorization of...

    onsite, Sioux Falls, SD, United States
    $60k/yrFull TimeJunior (<2 years)
  • Cinemark

    Cinemark

    19 days ago

    Part time assistant manager

    Join Our Team: A career at Cinemark means you'll have epic opportunities to immerse yourself in our industry. But that's just the beginning — a front row seat means incredible growth as you bring new...

    onsite, Sioux Falls, SD, United States
    $33k – $36k/yrPart TimeEntry with Degree
  • Sanford Health

    Sanford Health

    20 days ago

    Medical assistant - ma - plastic surgery

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $38k – $51k/yrFull TimeEntry with Degree
  • Sanford Health

    Sanford Health

    20 days ago

    Senior patient access representative | medical oncology clinic | 40 hrs/week

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $36k – $50k/yrFull TimeSenior (5+ years)
  • Avera Health

    Avera Health

    21 days ago

    Medical assistant | hematology & bone marrow transplant clinic

    Location: Hematology, Transplant and Cellular Therapy Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate...

    onsite, Sioux Falls, SD, United States
    $40k – $56k/yrFull TimeEntry with Degree
  • Avera Health

    Avera Health

    22 days ago

    Registered nurse (rn) or licensed practical nurse (lpn) or medical assistant | obgyn

    Location: Avera Obstetrics & Gynecology Plaza 1 Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate...

    onsite, Sioux Falls, SD, United States
    $40k – $83k/yrFull TimeJunior (<2 years)
  • Sanford Health

    Sanford Health

    22 days ago

    Lpn - licensed practical nurse or ma - medical assistant - diabetes & thyroid clinic - ft days

    Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland....

    onsite, Sioux Falls, SD, United States
    $38k – $58k/yrFull TimeJunior (<2 years)
  • Avera Health

    Avera Health

    22 days ago

    Registered nurse (rn) or licensed practical nurse (lpn) or medical assistant | mcgreevy 7th ave clinic

    Location: Avera 7th Avenue Clinic Worker Type: Regular Work Shift: Day Shift (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon...

    onsite, Sioux Falls, SD, United States
    $40k – $83k/yrFull TimeJunior (<2 years)

10,000,000+ more jobs available!