Job Description Summary

Executive Clinical Program Leader - Translational Clinical Oncology

Location: Cambridge, MA, USA
Work Arrangement: Onsite
Employment Type: Full-Time
Req ID: REQ-10060719

Job Description

The Executive Clinical Program Leader (ECPL) provides strategic medical and scientific leadership for the development of multiple experimental agents within the Translational Clinical Oncology (TCO) portfolio. The role spans from early target identification through transition into later-stage development, partnering closely with development teams to accelerate decision-making and portfolio advancement. The ECPL also provides scientific and clinical expertise to evaluate external innovation opportunities and business development initiatives.

Key Responsibilities

• Provide strategic medical and scientific leadership across early oncology development programs.
• Represent Translational Clinical Oncology programs at internal governance and leadership boards.
• Lead clinical strategy development and provide senior clinical input for clinical studies and preclinical research projects.
• Review and provide feedback on key study documents, including protocols, investigator brochures, and regulatory submissions.
• Contribute scientific and clinical expertise to business development, licensing evaluations, and portfolio reviews.
• Lead and oversee external collaborations and strategic partnerships.
• Mentor colleagues and serve as an expert resource across Biomedical Research and the broader organization.
• Ensure the safe, ethical, and compliant conduct of clinical trials in accordance with GCP and company procedures.
• Engage with external experts, investigators, and health authorities in support of early oncology clinical development.
• Contribute to scientific publications, abstracts, and presentations for internal and external audiences.

Essential Requirements

• MD required; MD/PhD preferred.
• Board certification (or equivalent expertise) in Hematology-Oncology.
• 7+ years of experience leading complex global early-phase hematology-oncology clinical programs within the pharmaceutical or biotechnology industry.
• Strong experience in translational hematology/oncology and clinical research.
• Recognized scientific and clinical expertise demonstrated through publications and professional contributions.
• Broad knowledge of oncology drug development and clinical trial execution.
• Excellent written and verbal communication skills.
• Proven leadership and people management experience.
• Strong mentoring and talent development capabilities.
• High ethical standards and commitment to improving outcomes for patients with cancer.

Rewards

At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen. The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks paid parental leave.

Expected Annual Base Salary Range for role:

USA: $288,400.00 - 535,600.00 USD Annual

The salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically. In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Further details will be provided during the application process.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.